Výsledky vyhledávání - "Eun Shin Park"

Thyrotropin Modulates Interferon-γ-Mediated Intercellular Adhesion Molecule-1 Gene Expression by Inhibiting Janus Kinase-1 and Signal Transducer and Activator of Transcription-1 Activation in Thyroid Cells*

Autor: Jae Mi Suh, O-Yu Kwon, Ho Kim, Heung Kyu Ro, Jeong Hoon Kim, Soo Jung Park, Eun Shin Park, Dohoon Kim, Minho Shong, Jongkyeong Chung, Hyo Kyun Chung

Publikováno v: Endocrinology. 141:2090-2097

TSH is known as an important hormone that plays the major role not only in the maintenance of normal physiology but also in the regulation of immunomodulatory gene expression in thyrocytes. The adhesion molecule intercellular adhesion molecule-1 (ICA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e634b2391499d9d882a67b9b679e93
https://doi.org/10.1210/endo.141.6.7507

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Role of Peroxiredoxins in Regulating Intracellular Hydrogen Peroxide and Hydrogen Peroxide-induced Apoptosis in Thyroid Cells

Autor: Heung Kyu Ro, Soo Jung Park, Minho Shong, Eun Shin Park, Jae Mi Suh, Hyo Kyun Chung, O-Yu Kwon, Young Kun Kim, Ho Kim, Tae Hoon Lee

Publikováno v: Journal of Biological Chemistry. 275:18266-18270

Peroxiredoxins (Prxs) play an important role in regulating cellular differentiation and proliferation in several types of mammalian cells. One mechanism for this action involves modulation of hydrogen peroxide (H(2)O(2))-mediated cellular responses.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0022f454403f547f5293ac338ea1b4
https://doi.org/10.1074/jbc.275.24.18266

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Involvement of JAK/STAT (Janus Kinase/Signal Transducer and Activator of Transcription) in the Thyrotropin Signaling Pathway

Autor: O-Yu Kwon, Soon Hee You, Soo Jung Park, Bo Youn Cho, Ho Kim, Minho Shong, Jae Mi Suh, Heung Kyu Ro, Eun Shin Park, Kang Wook Lee, Jongkyeong Chung, Hyo Kyun Chung, Young Kun Kim

Publikováno v: Molecular Endocrinology. 14:662-670

TSH is an important physiological regulator of growth and function in thyroid gland. The mechanism of action of TSH depends on interaction with its receptor coupled to heterotrimeric G proteins. We show here that TSH induces the phosphorylation of ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7959cadd10c3fffcc2bb190fc57442
https://doi.org/10.1210/mend.14.5.0458

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Hormone-Dependent Regulation of Intercellular Adhesion Molecule-1 Gene Expression: Cloning and Analysis of 5′-Regulatory Region of Rat Intercellular Adhesion Molecule-1 Gene in FRTL-5 Rat Thyroid Cells

Autor: Heung Kyu Ro, Soon Hee You, O-Yu Kwon, Bo Youn Cho, Ho Kim, Minho Shong, Leonard D. Kohn, Shin-ichi Taniguchi, Eun Shin Park

Publikováno v: Thyroid. 9:601-612

Intercellular adhesion molecule-1 (ICAM-1) has been suggested to play an important role in the perpetuation of autoimmune thyroid disease. To clarify the regulation of ICAM-1 gene in thyroid cells, we investigated ICAM-1 expression in the FRTL-5 thyr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31a7a4b1edc65adc6a63479e4ff6c13
https://doi.org/10.1089/thy.1999.9.601

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Thyrotropin induces SOCS-1 (suppressor of cytokine signaling-1) and SOCS-3 in FRTL-5 thyroid cells

Autor: Heung Kyu Ro, Ho Kim, O-Yu Kwon, Minho Shong, Jae Mi Suh, Eun Shin Park, Soo Jung Park, Bo Youn Cho, Jongkyeong Chung, Young Kun Kim

Publikováno v: Molecular endocrinology (Baltimore, Md.). 14(3)

TSH has multiple physiological roles: it is required for growth, differentiation, and function of the thyroid gland, and it regulates transcription of interferon-gamma (IFN-gamma)-responsive genes in thyrocytes, including genes for the major histocom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cce8d06b5f6ad723a9dbd53f41bcec
https://pubmed.ncbi.nlm.nih.gov/10707961

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