Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Eun Ryoung Jang"'
Autor:
Eric C. Rouchka, Myoungkun Jeoung, Eun Ryoung Jang, Jinpeng Liu, Chi Wang, Xiaohong Li, Emilia Galperin
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 770-778 (2016)
The Suppressor of Clear, Caenorhabditis elegans Homolog (SHOC2) is a scaffold protein that positively modulates activity of the RAS/ERK1/2 MAP kinase signaling cascade. We set out to understand the ERK1/2 pathway transcriptional response transduced t
Externí odkaz:
https://doaj.org/article/b75d814d66eb4b809d76aa0e3f6f7349
Autor:
Eun Ryoung Jang, Emilia Galperin
Publikováno v:
Communicative & Integrative Biology, Vol 9, Iss 4 (2016)
The extracellular signal-regulated kinase (ERK1/2) cascade regulates a myriad of functions in multicellular organisms. Scaffold proteins provide critical spatial and temporal control over the specificity of signaling. Shoc2 is a scaffold that acceler
Externí odkaz:
https://doaj.org/article/5e3efc5766d54b9680ed9fec0d56b33a
Autor:
Ji Eun Park, Lin Ao, Zachary Miller, Kyungbo Kim, Ying Wu, Eun Ryoung Jang, Eun Young Lee, Kyung Bo Kim, Wooin Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73732 (2013)
The proteasome is a key regulator of cellular protein homeostasis and is a clinically validated anticancer target. The immunoproteasome, a subtype of proteasome expressed mainly in hematopoietic cells, was initially recognized for its role in antigen
Externí odkaz:
https://doaj.org/article/ea6497ba13cb41049fd2f004751abb4a
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66067 (2013)
Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases 1 and 2 (ERK1/2). Shoc2 is also proposed to interact with RAS and Raf-1 in order to accelerate ERK1/2 activity. To understand the mechanisms by which Shoc2 r
Externí odkaz:
https://doaj.org/article/3d1174457f894f2b8165636f5a3565f1
Autor:
Lina Abdelmoti, Malathy Palayam, Rebecca Norcross, Eun Ryoung Jang, Patricia G. Wilson, Emilia Galperin
Publikováno v:
J Cell Sci
The ERK1/2 (also known as MAPK3 and MAPK1, respectively) signaling pathway is critical in organismal development and tissue morphogenesis. Deregulation of this pathway leads to congenital abnormalities with severe developmental dysmorphisms. The core
Publikováno v:
Molecular Biology of the Cell
Valosin-containing protein (VCP), also named p97, is an essential hexameric AAA+ ATPase with diverse functions in the ubiquitin system. Here we demonstrate that VCP is critical in controlling signals transmitted via the essential Shoc2-ERK1/2 signali
Multilayer regulatory mechanisms of ERK1/2 signals transmitted through the Shoc2 scaffolding complex
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
HyeIn Jang, Emilia Galperin, Jing Chen, Jamal Bryant, Matthew S. Gentry, Ping Shi, Eun Ryoung Jang, Vikas V. Dukhande, Myoungkun Jeoung
Publikováno v:
Molecular and Cellular Biology. 34:3579-3593
Scaffold proteins play a critical role in controlling the activity of the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway. Shoc2 is a leucine-rich repeat scaffold protein that acts as a positive modulator of ERK1/2 signaling. However, the
Autor:
Eun Ryoung Jang, Arthur1,2, Soo-Jeong Lim1, Eun Sook Lee, Arthur1, Gajin Jeong, Arthur2, Tae-You Kim3, Yung-Jue Bang3, Jong-Soo Lee1 leejs@ncc.re.kr
Publikováno v:
Oncogene. 3/4/2004, Vol. 23 Issue 9, p1724-1736. 13p. 1 Color Photograph, 1 Black and White Photograph, 4 Graphs.
Autor:
Emilia Galperin, Eun Ryoung Jang
Publikováno v:
Communicative & Integrative Biology
Communicative & Integrative Biology, Vol 9, Iss 4 (2016)
Communicative & Integrative Biology, Vol 9, Iss 4 (2016)
The extracellular signal-regulated kinase (ERK1/2) cascade regulates a myriad of functions in multicellular organisms. Scaffold proteins provide critical spatial and temporal control over the specificity of signaling. Shoc2 is a scaffold that acceler