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Akademický článek

Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model

Autor: Yeongmok Lee, Hyeon Seong Jeong, Seoyeon Jung, Junmo Hwang, Chi Truc Han Le, Sung-Hoon Jun, Eun Jo Du, KyeongJin Kang, Beom-Gi Kim, Hyun-Ho Lim, Sangho Lee

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Abstract The anion channel SLAC1 functions as a crucial effector in the ABA signaling, leading to stomata closure. SLAC1 is activated by phosphorylation in its intracellular domains. Both a binding-activation model and an inhibition-release model for

Externí odkaz: https://doaj.org/article/6d82d1cd955f4ad58c96c0c1949e4cc4

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Akademický článek

Electrospinning Nanofibers as a Dressing to Treat Diabetic Wounds

Autor: Eun Jo Jang, Rajkumar Patel, Madhumita Patel

Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1144 (2023)

Globally, diabetic mellitus (DM) is a common metabolic disease that effectively inhibits insulin production, destroys pancreatic β cells, and consequently, promotes hyperglycemia. This disease causes complications, including slowed wound healing, ri

Externí odkaz: https://doaj.org/article/fb998e0c6c2d433c9103aff7e0599099

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Akademický článek

A sensory-motor neuron type mediates proprioceptive coordination of steering in C. elegans via two TRPC channels.

Autor: Jihye Yeon, Jinmahn Kim, Do-Young Kim, Hyunmin Kim, Jungha Kim, Eun Jo Du, KyeongJin Kang, Hyun-Ho Lim, Daewon Moon, Kyuhyung Kim

Publikováno v: PLoS Biology, Vol 16, Iss 6, p e2004929 (2018)

Animal locomotion is mediated by a sensory system referred to as proprioception. Defects in the proprioceptive coordination of locomotion result in uncontrolled and inefficient movements. However, the molecular mechanisms underlying proprioception ar

Externí odkaz: https://doaj.org/article/7757988fd3bb4f769dd766c61971d61d

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Akademický článek

Nucleophile sensitivity of Drosophila TRPA1 underlies light-induced feeding deterrence

Autor: Eun Jo Du, Tae Jung Ahn, Xianlan Wen, Dae-Won Seo, Duk L Na, Jae Young Kwon, Myunghwan Choi, Hyung-Wook Kim, Hana Cho, KyeongJin Kang

Publikováno v: eLife, Vol 5 (2016)

Solar irradiation including ultraviolet (UV) light causes tissue damage by generating reactive free radicals that can be electrophilic or nucleophilic due to unpaired electrons. Little is known about how free radicals induced by natural sunlight are

Externí odkaz: https://doaj.org/article/04f0b3b9156a4ad9a03486658c028f0a

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Akademický článek

TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway.

Autor: Eun Jo Du, Tae Jung Ahn, Ilmin Kwon, Ji Hye Lee, Jeong-Ho Park, Sun Hwa Park, Tong Mook Kang, Hana Cho, Tae Jin Kim, Hyung-Wook Kim, Youngsoo Jun, Hee Jae Lee, Young Sik Lee, Jae Young Kwon, KyeongJin Kang

Publikováno v: PLoS Genetics, Vol 12, Iss 1, p e1005773 (2016)

Pathogen expulsion from the gut is an important defense strategy against infection, but little is known about how interaction between the intestinal microbiome and host immunity modulates defecation. In Drosophila melanogaster, dual oxidase (Duox) ki

Externí odkaz: https://doaj.org/article/23d169fbc8f54f5694ea0135d190804e

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