Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Eun J. Yoon"'
Publikováno v:
Journal of the American Chemical Society. 131:16147-16155
Highly monodispersed nanoparticles of a trivalent silver polydiguanide complex are synthesized by oxidation of the monovalent silver, followed by stabilization of the oxidized higher-valent metal through complexation with a polydiguanide ligand in a
Autor:
Jong Ho Cha, Dong Jo Chang, Jongwon Lee, Min Ji Kim, Seok Ho Kim, Chan Hee Park, Hwi Young Jung, Young-Ger Suh, Kyu-Won Kim, Do Yeon Kwon, Eun J. Yoon, Sun Ha Lim, Eung Chil Choi, Hyung Tae Yeo, Fu-Nan Li
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:6517-6526
The quinolone analog SQ-4004 has been identified as a potentially excellent anti-ischemic agent, which exhibited highly potent efficacy in reducing infarct volume size in vivo rat MCAO model (32.1% at 0.01mg/kg) and potent cardioprotective effect at
Autor:
Farhana Samrin, Su-Yeon Kim, Jeewoo Lee, Sadhna Puri, Eun J. Yoon, Taehee Kang, Sunghoon Kim, Farhanullah, Eung Chil Choi
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:7154-7159
Five new structural analogues of substituted-1H-quinolinones (19, 20, 23, 24, and 26) have been synthesized and evaluated for Staphylococcus aureus methionyl-tRNA synthetase enzyme inhibitory activity. These compounds were also tested against pathoge
Publikováno v:
Journal of the American Geriatrics Society. 47:784-791
OBJECTIVES: The purpose of this study was to test whether an intervention combining increased daytime physical activity with improvement in the nighttime environment improves sleep and decreases agitation in nursing home residents. DESIGN: A randomiz
Autor:
Hyun J. Shim, Woo I. Lee, Won B. Kim, Eun J. Yoon, Junnick Yang, Myung Gyoon Lee, Sang D. Lee
Publikováno v:
Biopharmaceutics & Drug Disposition. 17:373-420
The pharmacokinetics of M1, M2, M3, and/or M4 were compared after intravenous (iv) administration of DA-125 and/or ME2303 to mice (25 mg kg−1) and rats (5, 10, 20, 30, and 40 mg kg−1). The mean plasma concentrations of M1 were detected up to 8 h
Autor:
Won B. Kim, Eun J. Yoon, Myung Gyoon Lee, Woo H. Yoon, Yoon Kim, Hyun J. Shim, Sang D. Lee, Junnick Yang
Publikováno v:
Biopharmaceutics & Drug Disposition. 17:183-195
The pharmacokinetics of DA-125 were compared after intravenous (i.v.) administration of the drug, 10 mg kg-1, to control male Sprague-Dawley rats (n = 9) and uranyl nitrate-induced acute renal failure (U-ARF, n = 12) rats, or male Sprague-Dawley rats
Publikováno v:
International Journal of Pharmaceutics. 121:1-10
The pharmacokinetics and tissue distribution of adriamycin (ADM) and its metabolite, adriamycinol were investigated after intravenous (i.v.) injection of free ADM (treatment I), ADM-loaded neutral proliposomes (treatment II) and empty neutral prolipo
Autor:
Eung D. Lee, Won B. Kim, Yang Junnick, Sang D. Lee, Hyun J. Shim, Eun J. Yoon, Myung Gyoon Lee, Woo H. Yoon
Publikováno v:
International Journal of Pharmaceutics. 109:181-187
The pharmacokinetic parameters, tissue distribution and biliary excretion of M1-M4 were estimated after intravenous (i.v.) administration of DA-125, 2.5 mg per kg to beagle dogs. The mean values of the terminal half-life, mean residence time, total b
Publikováno v:
Biopharmaceutics & Drug Disposition. 15:391-407
The pharmacokinetics and tissue distribution of methotrexate (MTX) were investigated after intravenous (i.v.) injection of free MTX (treatment I), MTX-loaded proliposomes (treatment II), and empty proliposomes mixed manually with free MTX (treatment
Autor:
Hyun J. Shim, Junnick Yang, Eun J. Yoon, Myung Gyoon Lee, Won B. Kim, Eung D. Lee, Sang D. Lee
Publikováno v:
International Journal of Pharmaceutics. 103:147-154
The pharmacokinetics of DA-125 or its active metabolite, M1 (FT-ADM), an adriamycin analog containing fluorine were compared after intravenous (i.v.) administration of DA-125 or M1 in rats. DA-125, 20 mg kg−1 was dissolved in 1 mM lactic acid/0.9%