Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Eun Hye Joe"'
Autor:
Sushil Gaire, Jiawei An, Haijie Yang, Keon Ah Lee, Manisha Dumre, Eun Jeong Lee, Sang-Myun Park, Eun-Hye Joe
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract In this study, we examined how systemic inflammation affects repair of brain injury. To this end, we created a brain-injury model by stereotaxic injection of ATP, a damage-associated molecular pattern component, into the striatum of mice. Sy
Externí odkaz:
https://doaj.org/article/b022e10cf75b48c4a7e3e0eac1a94a9f
Publikováno v:
Neurobiology of Disease, Vol 197, Iss , Pp 106528- (2024)
Background: Brain injury has been suggested as a risk factor for neurodegenerative diseases. Accordingly, defects in the brain's intrinsic capacity to repair injury may result in the accumulation of damage and a progressive loss of brain function. Th
Externí odkaz:
https://doaj.org/article/cda3153376504798821f65380e1c04d2
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-19 (2021)
Abstract Background Endoplasmic reticulum (ER) stress is a common feature of Parkinson’s disease (PD), and several PD-related genes are responsible for ER dysfunction. Recent studies suggested LRRK2-G2019S, a pathogenic mutation in the PD-associate
Externí odkaz:
https://doaj.org/article/a4b1d46e484f45eda49e232e94783cc2
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Brain injury causes astrocytes to become reactive (astrogliosis). In this study, we compared astrogliosis in acutely injured cortex and striatum of adult FVB/N mice induced by stereotaxic injection of ATP, a component of danger-associated mo
Externí odkaz:
https://doaj.org/article/4b300607bebb46c29c01e5761d54b25b
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-19 (2019)
Abstract Multifunctional signal transducer and activator of transcription (STAT) proteins play important roles in cancer. Here, we have shown that STAT6 is epigenetically silenced in some cases of malignant glioblastoma, which facilitates cancer cell
Externí odkaz:
https://doaj.org/article/9655401f2b7a4e47888d94c1c10cbe00
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 482-491 (2019)
Dysfunctional regulation of inflammation may contribute to the progression of neurodegenerative diseases. The results of this study revealed that DJ-1, a Parkinson's disease (PD) gene, regulated expression of prostaglandin D2 synthase (PTGDS) and pro
Externí odkaz:
https://doaj.org/article/86d0de2bc78c4ab882a30a171a661813
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-19 (2019)
Abstract Accumulating evidence indicates that endoplasmic reticulum (ER) stress is a common feature of Parkinson’s disease (PD) and further suggests that several PD-related genes are responsible for ER dysfunction. However, the underlying mechanism
Externí odkaz:
https://doaj.org/article/0ce50860152041fb891b5b3f15b67fe0
Autor:
Min Jung, Kwon, Yeojin, Seo, Hana, Cho, Hyung Soon, Kim, Young Joo, Oh, Simay, Genişcan, Minjae, Kim, Hee Hwan, Park, Eun-Hye, Joe, Myung-Hee, Kwon, Han Chang, Kang, Byung Gon, Kim
Publikováno v:
Theranostics. 12:5856-5876
Preconditioning nerve injury enhances axonal regeneration of dorsal root ganglia (DRG) neurons in part by driving pro-regenerative perineuronal macrophage activation. How these macrophages influence the neuronal capacity of axon regeneration remains
Publikováno v:
Neurobiology of Disease, Vol 83, Iss , Pp 90-99 (2015)
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease. Although the etiology of PD has not yet been fully understood, accumulating evidence indicates that neuroinflammation plays a critical role in the progression of PD. α-
Externí odkaz:
https://doaj.org/article/47ba46b6c59c48edbb09286b858f3eb1
Autor:
Haijie Yang, Dong Wan Ko, Ilo Jou, Eun-Hye Joe, Sang Myun Park, Dong-Joo Choi, Jae-Kyung Kwon
Publikováno v:
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
Astrocytes are activated in response to brain damage. Here, we found that expression of Kir4.1, a major potassium channel in astrocytes, is increased in activated astrocytes in the injured brain together with upregulation of the neural stem cell mark