Zobrazeno 1 - 10 of 91 pro vyhledávání: '"Eun Hye Jeong"'
1
Akademický článek
Motor subtypes and clinical characteristics in sporadic and genetic Parkinson's disease groups: analysis of the PPMI cohort
Autor: Eun Hye Jeong, Jae Yong Lee, Sun-Ku Han, Yoo Sung Song
Publikováno v: Frontiers in Neurology, Vol 14 (2023)
IntroductionThe extensive clinical variations observed in Parkinson's disease (PD) pose challenges in early diagnosis and treatment initiation. However, genetic research in PD has significantly transformed the clinical approach to its treatment. More
Externí odkaz: https://doaj.org/article/9eb2b86f68964426ab3eb97fc1fef15b
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2
Akademický článek
The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system
Autor: Chang Hoon Ji, Hee Yeon Kim, Min Ju Lee, Ah Jung Heo, Daniel Youngjae Park, Sungsu Lim, Seulgi Shin, Woo Seung Yang, Chang An Jung, Kun Young Kim, Eun Hye Jeong, Sun Ho Park, Su Bin Kim, Su Jin Lee, Jeong Eun Na, Ji In Kang, Hyung Min Chi, Hyun Tae Kim, Yun Kyung Kim, Bo Yeon Kim, Yong Tae Kwon
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Targeted protein degradation is a promising approach for basic research and therapeutic applications. Here, the authors develop a targeted protein degradation platform called AUTOTAC to degrade oncoproteins and neurodegeneration-associated proteins v
Externí odkaz: https://doaj.org/article/b40a23bb612c4deeb02c237334426aad
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3
Akademický článek
Serial changes of I-123 FP-CIT SPECT binding asymmetry in Parkinson's disease: Analysis of the PPMI data
Autor: Eun Hye Jeong, Mun Kyung Sunwoo, Jae Yong Lee, Sun-Ku Han, Sung Wook Hyung, Yoo Sung Song
Publikováno v: Frontiers in Neurology, Vol 13 (2022)
BackgroundDopaminergic denervation and motor symptoms are usually asymmetric at the onset of Parkinson's disease (PD). In this study, we estimated the asymmetry of specific binding ratio (SBR) of I-123 FP-CIT SPECT images during 4-years of follow up,
Externí odkaz: https://doaj.org/article/ba8a0cbf67e041d9ac16d7cd5ba83994
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4
Akademický článek
Correlation of Dopaminergic Denervation and the Progression of Autonomic Dysfunctions in Different Clinical Subtypes of Parkinson’s Disease
Autor: Eun Hye Jeong, Mun Kyung Sunwoo, Sung Wook Hyung, Sun-Ku Han, Jae Yong Lee
Publikováno v: Parkinson's Disease, Vol 2021 (2021)
Background. Autonomic dysfunctions occur in the early stage of Parkinson’s disease (PD) and impact the quality of life during the progression of the disease. In this study, we evaluated the serial progression of autonomic dysfunctions between diffe
Externí odkaz: https://doaj.org/article/59a802e46a014950bb9b5f05767775f7
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8
Akademický článek
Serial I-123-FP-CIT SPECT Image Findings of Parkinson's Disease Patients With Levodopa-Induced Dyskinesia
Autor: Eun Hye Jeong, Mun Kyung Sunwoo, Yoo Sung Song
Publikováno v: Frontiers in Neurology, Vol 9 (2018)
Background: Levodopa-induced dyskinesia (LID) is a major complication of dopamine replacement drug usage in Parkinson's disease (PD) patients. Since the mechanism of LID is yet unclear, we analyzed serial [I-123] N-ω-fluoropropyl-2β-carbomethoxy-3
Externí odkaz: https://doaj.org/article/a1dda0f859fa4a0ab6ee905ea1ed5b36
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9
Mining of a novel esterase (est3S) gene from a cow rumen metagenomic library with organosphosphorus insecticides degrading capability: Catalytic insights by site directed mutations, docking, and molecular dynamic simulations
Autor: Hee Yul Lee, Harun M. Patel, Du Yong Cho, Min Ju Kim, Kye Man Cho, Jea Gack Jung, Iqrar Ahmad, Eun Hye Jeong, Md. Azizul Haque
Publikováno v: International Journal of Biological Macromolecules. 190:441-455
A novel esterase (est3S) gene, 1026 bp in size, was cloned from a metagenomic library made of uncultured microorganisms from the contents of cow rumen. The esterolytic enzyme (Est3S) is composed of 342 amino acids and shows the highest identity with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b0df6d988ac12369720a77c366919e
https://doi.org/10.1016/j.ijbiomac.2021.08.224
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