Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Eun Hae Jang"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Neurodegenerative diseases (NDDs) are characterized by the progressive loss of selectively vulnerable populations of neurons, which is responsible for the clinical symptoms. Although degeneration of neurons is a prominent feature that undoubtedly con
Externí odkaz:
https://doaj.org/article/acb0011d669646d29ec155684d92f1cd
Autor:
Dae-Hyeon Song, Chang Woo Song, Jinkyoung Chung, Eun-Hae Jang, Hyunwoo Kim, Yongsuk Hur, Eun-Mi Hur, Doory Kim, Jae-Byum Chang
Publikováno v:
Nanoscale Advances. 5:1636-1650
A new imaging techniques, named Decoration Microscopy (DecoM) and Deco-Expansion Microscopy (Deco-ExM), facilitate molecular bioimaging through SEM and BF.
Autor:
Ga Ram Jeong, Eun-Hae Jang, Jae Ryul Bae, Soyoung Jun, Ho Chul Kang, Chi-Hu Park, Joo-Ho Shin, Yukio Yamamoto, Keiko Tanaka-Yamamoto, Valina L. Dawson, Ted M. Dawson, Eun-Mi Hur, Byoung Dae Lee
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2018)
Abstract Background Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial and sporadic Parkinson’s disease (PD). Elevated kinase activity is associated with LRRK2 toxicity, but the substrates that mediate neurodege
Externí odkaz:
https://doaj.org/article/82ef80fe0e5944a3bd82d33b19606f98
Autor:
Chae-Seok Lim, Hye Jin Nam, Jaehyun Lee, Dongha Kim, Ja Eun Choi, SukJae Joshua Kang, Somi Kim, Hyopil Kim, Chuljung Kwak, Kyu-Won Shim, Siyong Kim, Hyoung-Gon Ko, Ro Un Lee, Eun-Hae Jang, Juyoun Yoo, Jaehoon Shim, Md Ariful Islam, Yong-Seok Lee, Jae-Hyung Lee, Sung Hee Baek, Bong-Kiun Kaang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Lysine-specific demethylase 1 (LSD1) is a histone demethylase that participates in transcriptional repression or activation. Recent studies reported that LSD1 is involved in learning and memory. Although LSD1 phosphorylation by PKCα was imp
Externí odkaz:
https://doaj.org/article/0d31f3b5d7f647abb2626298419871e9
Autor:
Sang Chul Shin, Sun-Kyoung Im, Eun-Hae Jang, Kyeong Sik Jin, Eun-Mi Hur, Eunice EunKyeong Kim
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1357-1367.e5 (2019)
Summary: Katanin was the first microtubule (MT)-severing enzyme discovered, but how katanin executes MT severing remains poorly understood. Here, we report X-ray crystal structures of the apo and ATPγS-bound states of the catalytic AAA domain of hum
Externí odkaz:
https://doaj.org/article/5edffdc483ac4088863e58112c52ba6a
Autor:
Hyun-Jun Suh, Jong Bae Park, Yun-Hee Bae, Yunho Gim, Subin Kim, Eun Mo Yang, Seong-Min Park, Eun-Hae Jang, Eun Mi Hur
Publikováno v:
Journal of Neuroscience Research. 99:2874-2887
Axons in the adult mammalian central nervous system fail to regenerate after injury. By contrast, spontaneous axon regeneration occurs in the peripheral nervous system (PNS) due to a supportive PNS environment and an increase in the intrinsic growth
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Several studies have demonstrated the therapeutic potential of applying microtubule- (MT-) stabilizing agents (MSAs) that cross the blood-brain barrier to promote axon regeneration and prevent axonal dystrophy in rodent models of spinal cord injury a
Externí odkaz:
https://doaj.org/article/8d556cc2292646e69e90d9dea7e57bde
Publikováno v:
BMB Reports
Recent evidence from genetics, animal model systems and biochemical studies suggests that defects in membrane trafficking play an important part in the pathophysiology of Parkinson's disease (PD). Mutations in leucine-rich repeat kinase 2 (LRRK2) con
Autor:
Somi Kim, Ki Jun Yoon, Min Jung Kim, Jae-Hyun Lee, Hye-Ryeon Lee, Ji-il Kim, Bong-Kiun Kaang, Yeseul Lee, Eun-Hae Jang, Dae Hee Han, Hyoung-Gon Ko, Pojeong Park, Chaery Lee, Young-Yun Kong
Publikováno v:
HippocampusREFERENCES. 30(11)
Neur1 and Neur2, mouse homologs of the Drosophila neur gene, consist of two neuralized homology repeat domains and a RING domain. Both Neur1 and Neur2 are expressed in the whole adult brain and encode E3 ubiquitin ligases, which play a crucial role i
β-Adrenergic signaling is required for the induction of a labile state during memory reconsolidation
Autor:
Eun Hae Jang, Jihae Oh, Jaehyun Lee, Chae-Seok Lim, Chuljung Kwak, Jae-Ick Kim, Bong-Kiun Kaang
Publikováno v:
Brain Research Bulletin. 141:50-57
Memory reconsolidation is the process by which previously consolidated memories reenter a labile state through reactivation of the memory trace and are actively consolidated through de novo protein synthesis. Although extensive studies have shown tha