Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Eun Cheng Suh"'
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Akademický článek
Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25–35
Autor: Youn Young Lee, Jong In Han, Kyung Eun Lee, Sooyoung Cho, Eun Cheng Suh
Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)
Alzheimer’s disease (AD), one of the most prevalent neurodegenerative diseases is associated with pathological autophagy-lysosomal pathway dysfunction. Dexmedetomidine (Dex) has been suggested as an adjuvant to general anesthesia with advantages in
Externí odkaz: https://doaj.org/article/1071790903164797a9271003688a042a
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Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25-35
Autor: Youn Young Lee, Jong In Han, Sooyoung Cho, Eun Cheng Suh, Kyung Eun Lee
Current evidence suggests that dexmedetomidine (Dex) can be used as an adjuvant to general anesthesia for the elderly with or without neurodegenerative diseases, such as Alzheimer's disease (AD), since it has perioperative analgesic properties and ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2343a23ce49056f1cd3c5ead195aa23
https://doi.org/10.21203/rs.3.rs-2008282/v1
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4
The recovery from transient cognitive dysfunction induced by propofol was associated with enhanced autophagic flux in normal healthy adult mice
Autor: Hee Jung Baik, Kyung Eun Lee, Jong In Han, Yeonjoo Jung, Sooyoung Cho, Eun Cheng Suh, Guie Yong Lee
Publikováno v: Brain research. 1700
Propofol is the most widely accepted intravenous anesthetic available for clinical use. However, neurotoxicity of propofol in the developing brain has been reported. This study investigated the effects of propofol on cognitive function in normal heal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08b252dd584a23889d232c85f644c7f
https://pubmed.ncbi.nlm.nih.gov/30006294
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Knockout of Toll-like receptor 2 attenuates Aβ25–35-induced neurotoxicity in organotypic hippocampal slice cultures
Autor: Yeonjoo Jung, Yul A. Kim, Eun Mi Park, Sung Joong Lee, Eun Cheng Suh, Kyung Eun Lee
Publikováno v: Neurochemistry International. 63(8):818-825
Toll-like receptors (TLRs), which have been implicated in various neuroinflammatory responses, are thought to act in defense mechanisms by inhibiting neuronal cell death in Alzheimer’s disease. In this study, we evaluated the effects of TLR2 on amy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c6b6075a3f9d11a1e1bc84743bbb5a
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6
Oxygen/Glucose Deprivation and Reperfusion Cause Modifications of Postsynaptic Morphology and Activity in the CA3 Area of Organotypic Hippocampal Slice Cultures
Autor: Yeonjoo Jung, Eun Cheng Suh, Kyung Eun Lee
Publikováno v: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
Brain ischemia leads to overstimulation of N-methyl-D-aspartate (NMDA) receptors, referred as excitotoxicity, which mediates neuronal cell death. However, less attention has been paid to changes in synaptic activity and morphology that could have an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cdff218184f472fb270461dadf00ef
http://europepmc.org/articles/PMC3526747
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Role of microglial IKKβ in kainic acid-induced hippocampal neuronal cell death
Autor: Sung Joong Lee, Jong Eun Lee, Jinpyo Hong, Ik Hyun Cho, Chong Hyun Kim, Kyung Eun Lee, Eun Cheng Suh, Michael Karin, Hyunkyoung Lee, Dong Woon Kim, Eun-Kyeong Jo, Soojin Lee, Jae Hwan Kim
Publikováno v: Brain. 131:3019-3033
Microglial cells are activated during excitotoxin-induced neurodegeneration. However, the in vivo role of microglia activation in neurodegeneration has not yet been fully elucidated. To this end, we used Ikkbeta conditional knockout mice (LysM-Cre/Ik
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0da58a3b1e2bc11f3a60330b65c9886
https://doi.org/10.1093/brain/awn230
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Microglial Toll-like receptor 2 contributes to kainic acid-induced glial activation and hippocampal neuronal cell death
Autor: Eun Cheng Suh, Eun-Kyeong Jo, Jinsoo Seo, Kyung Eun Lee, Sung Joong Lee, Se-Young Choi, Soojin Lee, Jinpyo Hong, Hyun Jung Min, Seung Hwa Park, Ik Hyun Cho, Kyung Il Kwak, Chong Hyun Kim
Publikováno v: The Journal of biological chemistry. 285(50)
Recent studies indicate that Toll-like receptors (TLRs), originally identified as infectious agent receptors, also mediate sterile inflammatory responses during tissue damage. In this study, we investigated the role of TLR2 in excitotoxic hippocampal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6511f892f08a033107f4769e0f794701
https://pubmed.ncbi.nlm.nih.gov/20923777
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9
A beta 25-35 induces presynaptic changes in organotypic hippocampal slice cultures
Autor: Eun Cheng Suh, Eun Mi Park, Yul A. Kim, Kyung Eun Lee, Yeonjoo Jung
Publikováno v: Neurotoxicology. 29(4)
Memory loss in Alzheimer's disease (AD) may be related to synaptic defects in damaged hippocampal neurons. We investigated the relationship between amyloid peptide A beta 25-35-induced neuronal death pattern and presynaptic changes in organotypic hip
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdac4666fca25c2f6dd6e27c91d0f60
https://pubmed.ncbi.nlm.nih.gov/18502514
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