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pro vyhledávání: '"Eui-Yun Kim"'
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 4, Pp 643-657 (2020)
Cancer: Keeping chromosomes stable during cell division Signaling through cGAS, a protein that detects DNA in the cytosol, prevents chromosome instability (CIN) in cancer cells by regulating the levels of the cell-cycle inhibitor p21. Alterations in
Externí odkaz:
https://doaj.org/article/cad4694a39e74c20b83c409e850365a4
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 4, Pp 643-657 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Chromosomal instability (CIN) in cancer cells has been reported to activate the cGAS–STING innate immunity pathway via micronuclei formation, thus affecting tumor immunity and tumor progression. However, adverse effects of the cGAS/STING pathway as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bb6c9d4a0fb2bcaf1e4365f205ea28
https://doaj.org/article/cad4694a39e74c20b83c409e850365a4
https://doaj.org/article/cad4694a39e74c20b83c409e850365a4