Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Eui Hwa Jang"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Coronary artery bypass graft (CABG) is generally used to treat complex coronary artery disease. Treatment success is affected by neointimal hyperplasia (NIH) of graft and anastomotic sites. Although sirolimus and rosuvastatin indi
Externí odkaz:
https://doaj.org/article/8556b3b8e1ec4fc0b3858c2b56329d73
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115702- (2023)
Intimal hyperplasia (IH) is a major cause of vascular restenosis after bypass surgery, which progresses as a series of processes from the acute to chronic stage in response to endothelial damage during bypass grafting. A strategic localized drug deli
Externí odkaz:
https://doaj.org/article/ba8052e908eb4c79bee9297deefb6a2a
Autor:
Jung-Hwan Kim, Eui Hwa Jang, Ji-Yeon Ryu, Jiyong Lee, Jae Ho Kim, Wonhyoung Ryu, Young-Nam Youn
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3306 (2023)
We investigated the role of a sirolimus-embedded silk microneedle (MN) wrap as an external vascular device for drug delivery efficacy, inhibition of neointimal hyperplasia, and vascular remodeling. Using dogs, a vein graft model was developed to inte
Externí odkaz:
https://doaj.org/article/b8b3f4a7f01c41c99934cf257d4d83f5
Publikováno v:
Polymers, Vol 12, Iss 3, p 538 (2020)
Artificial vessels capable of long-term patency are essential clinical tools in vascular surgery that involves small vessels. On-going attempts to develop artificial vessels that complements restenosis have not been entirely successful. Here, we repo
Externí odkaz:
https://doaj.org/article/c1ed1cdaf60e40f69db6fa4b8857d168
Autor:
Dae-Hyun Kim, Eui Hwa Jang, Kang Ju Lee, Ji Yong Lee, Seung Hyun Park, Il Ho Seo, Kang Woog Lee, Seung Hyun Lee, WonHyoung Ryu, Young-Nam Youn
Publikováno v:
Polymers, Vol 9, Iss 2, p 56 (2017)
Restenosis at a vascular anastomosis site is a major cause of graft failure and is difficult to prevent by conventional treatment. Perivascular drug delivery has advantages as drugs can be diffused to tunica media and subintima while minimizing the d
Externí odkaz:
https://doaj.org/article/f618b435547e48d2b83723cbbfe3887c
Autor:
Young-Nam Youn, KangJu Lee, Seunghyun Park, Jiyong Lee, Jae Ho Kim, Jung-Hwan Kim, Eui Hwa Jang, Yosup Kang, Sanghyun Park, WonHyoung Ryu
Publikováno v:
Journal of Controlled Release. 340:125-135
Various perivascular drug delivery techniques have been demonstrated for localized post-treatment of intimal hyperplasia: a vascular inflammatory response caused by endothelial damages. Although most perivascular devices have focused on controlling t
Autor:
Jae Chul Hwang, Moohyun Kim, Sumin Kim, Hunkyu Seo, Soohwan An, Eui Hwa Jang, Seung Yeop Han, Mi Jung Kim, Nam Kyun Kim, Seung-Woo Cho, Sak Lee, Jang-Ung Park
Publikováno v:
Science Advances. 8
The in situ diagnosis of cardiac activities with simultaneous therapeutic electrical stimulation of the heart is key to preventing cardiac arrhythmia. Here, we present an unconventional single-device platform that enables in situ monitoring even in a
Publikováno v:
Journal of cardiovascular translational research. 15(5)
Although autologous vein grafting is essential, the high vein failure rate and specific clinical interventions are not clear, so a potential treatment is critically needed; thus, complex analyses of the relationship between pathobiological and physio
Autor:
Il Ho Seo, Youngjoo Park, Young-Nam Youn, Seung Hyun Park, KangJu Lee, WonHyoung Ryu, Dae Hyun Kim, Eui Hwa Jang, Ji Yong Lee
Publikováno v:
Journal of Controlled Release. 268:237-246
After surgical procedures such as coronary/peripheral bypass grafting or endarterectomy for the treatment of organ ischemia derived from atherosclerosis, intimal hyperplasia (IH) which leads to restenosis or occlusion at the site of graft anastomosis
Publikováno v:
Polymers
Volume 12
Issue 3
Polymers, Vol 12, Iss 3, p 538 (2020)
Volume 12
Issue 3
Polymers, Vol 12, Iss 3, p 538 (2020)
Artificial vessels capable of long-term patency are essential clinical tools in vascular surgery that involves small vessels. On-going attempts to develop artificial vessels that complements restenosis have not been entirely successful. Here, we repo