Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eugenio A. Cefali"'
Autor:
Jean-claude Tardif, Sameh Fikry, Ginette Girard, Tania Discenza, Annik Fortier, Eugenio A Cefali, Marie-Claude Guertin
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Background: 1-methylnicotinamide, a nicotinic acid metabolite, is TRIA-662’s active component. As part of a pilot study, we assessed TRIA-662’s effects on inflammatory biomarkers and blood lipids. Methods: Patients aged 18-80 years with mean seru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2560b2b1fb884e0e39a359dfd9cc519a
https://doi.org/10.1161/atvb.37.suppl_1.542
https://doi.org/10.1161/atvb.37.suppl_1.542
Publikováno v:
Biopharmaceutics & Drug Disposition. 30:508-516
Acipimox is an analog of nicotinic acid and is indicated for the treatment of dyslipidemia. It is also believed to improve glucose control by enhancing insulin sensitivity. The purpose of this study was to direct modified release (MR) formulation str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca766d5a89a5b19425bd378d298a3cf
https://doi.org/10.1002/bdd.683
https://doi.org/10.1002/bdd.683
Publikováno v:
Biopharmaceutics & Drug Disposition. 28:297-306
Lovastatin and extended-release (ER) niacin in a fixed dose combination (Advicor®) is approved for the treatment of dyslipidemia. Since both drugs are extensively metabolized, this study investigated the bioavailability and pharmacokinetics of their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6372baa7ed101391c1e09ad42bbdbc92
https://doi.org/10.1002/bdd.555
https://doi.org/10.1002/bdd.555
Publikováno v:
International Journal of Pharmaceutics. 127:147-154
A study in beagle dogs was carried out to estimate the bioavailability of silicon and aluminum from Zeolite A administered as a capsule, oral suspension, and oral solution relative to an intravenous bolus infusion (i.v.) administered over a 1-1.5 min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11bdf6c79c419698d70541e7f6302736
https://doi.org/10.1016/0378-5173(95)04110-9
https://doi.org/10.1016/0378-5173(95)04110-9
Publikováno v:
Pharmaceutical Research. 12:270-274
Zeolite A is a synthetic zeolite which may have therapeutic utility in osteoporotic individuals because of its ability to stimulate bone formation. A study of Zeolite A (30 mg/kg), sodium aluminosilicate (16 mg/kg), magnesium trisilicate (20 mg/kg),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73587a5b3e57c09fba2e830321749e03
https://doi.org/10.1023/a:1016291228957
https://doi.org/10.1023/a:1016291228957
Autor:
J H Leu, Rajeev M. Menon, Marijke H. Adams, Eugenio A. Cefali, Dwain Tolbert, Mario A. Gonzalez
Publikováno v:
International journal of clinical pharmacology and therapeutics. 45(8)
Objective To characterize plasma and urine pharmacokinetics of niacin and its metabolites after oral administration of 2,000 mg of extended-release (ER) niacin in healthy male volunteers. Methods Niacin ER was administered to 12 healthy male subjects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859ea5626049005595ea6dd4caa0702c
https://pubmed.ncbi.nlm.nih.gov/17725178
https://pubmed.ncbi.nlm.nih.gov/17725178
Autor:
Marijke H. Adams, Eugenio A. Cefali, Dwain Tolbert, Rajeev M. Menon, Mario A. Gonzalez, Jocelyn H. Leu
Publikováno v:
Journal of clinical pharmacology. 47(6)
The metabolic profile of niacin is influenced by the rate of niacin administration. This study characterizes the effect of administration rate on the pharmacokinetics of niacin and its metabolites. Twelve healthy males were enrolled in an open-label,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86e558b7bf1be312d28178dd41393f4
https://pubmed.ncbi.nlm.nih.gov/17463214
https://pubmed.ncbi.nlm.nih.gov/17463214
Publikováno v:
Journal of Pharmaceutical Sciences. 83:758-760
A pharmacokinetic study of the dopamine D2 receptor agonist (S)-(-)-2-(N-propyl-N-(2-thienylethyl)amino)-5-hydroxytetralin+ ++-HCl (N-0923) infused in female cynomolgus monkeys over a 4-h period was carried out at International Research and Developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91c9a118f6b87eb4ea9eab943c77a6e
https://doi.org/10.1002/jps.2600830533
https://doi.org/10.1002/jps.2600830533
Autor:
Domenic A. Sica, Itaf Fakhry, Geoffrey Allan, Denise Lowe Walters, Eugenio A. Cefali, Don Farthing
Publikováno v:
Biomedical chromatography : BMC. 8(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdc7b0bb216f03f4a062063257f66ce
https://pubmed.ncbi.nlm.nih.gov/7841771
https://pubmed.ncbi.nlm.nih.gov/7841771
Publikováno v:
Journal of pharmaceutical sciences. 80(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8fb6e0f2dcae0669a8354ee3110979
https://pubmed.ncbi.nlm.nih.gov/1783995
https://pubmed.ncbi.nlm.nih.gov/1783995