Problems of Connectionism

Autor: Marta Vassallo, Davide Sattin, Eugenio Parati, Mario Picozzi

Publikováno v: Philosophies, Vol 9, Iss 2, p 41 (2024)

The relationship between philosophy and science has always been complementary. Today, while science moves increasingly fast and philosophy shows some problems in catching up with it, it is not always possible to ignore such relationships, especially

Externí odkaz: https://doaj.org/article/5973c964108f49a5b43a1f343e5aa52a

Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells

Autor: Valentina Coccè, Silvia La Monica, Mara Bonelli, Giulio Alessandri, Roberta Alfieri, Costanza Annamaria Lagrasta, Denise Madeddu, Caterina Frati, Lisa Flammini, Daniela Lisini, Angela Marcianti, Eugenio Parati, Francesca Paino, Aldo Giannì, Giampietro Farronato, Angela Falco, Lorenzo Spaggiari, Francesco Petrella, Augusto Pessina

Publikováno v: Cells, Vol 10, Iss 6, p 1427 (2021)

Background: Malignant Pleural Mesothelioma (MPM) is an aggressive tumor that has a significant incidence related to asbestos exposure with no effective therapy and poor prognosis. The role of mesenchymal stromal cells (MSCs) in cancer is controversia

Externí odkaz: https://doaj.org/article/5043b2f15724475d949474c94b0dbd6f

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.

Autor: John W Cole, Huichun Xu, Kathleen Ryan, Thomas Jaworek, Nicole Dueker, Patrick McArdle, Brady Gaynor, Yu-Ching Cheng, Jeffrey O'Connell, Steve Bevan, Rainer Malik, Naveed Uddin Ahmed, Philippe Amouyel, Sheraz Anjum, Joshua C Bis, David Crosslin, John Danesh, Stefan T Engelter, Myriam Fornage, Philippe Frossard, Christian Gieger, Anne-Katrin Giese, Caspar Grond-Ginsbach, Weang Kee Ho, Elizabeth Holliday, Jemma Hopewell, M Hussain, W Iqbal, S Jabeen, Jim Jannes, Ayeesha Kamal, Yoichiro Kamatani, Sandip Kanse, Manja Kloss, Mark Lathrop, Didier Leys, Arne Lindgren, W T Longstreth, Khalid Mahmood, Christa Meisinger, Tiina M Metso, Thomas Mosley, Martina Müller-Nurasyid, Bo Norrving, Eugenio Parati, Annette Peters, Alessandro Pezzini, I Quereshi, Asif Rasheed, A Rauf, T Salam, Jess Shen, Agnieszka Słowik, Tara Stanne, Konstantin Strauch, Turgut Tatlisumak, Vincent N Thijs, Steffen Tiedt, Matthew Traylor, Melanie Waldenberger, Matthew Walters, Wei Zhao, Giorgio Boncoraglio, Stéphanie Debette, Christina Jern, Christopher Levi, Hugh Markus, James Meschia, Arndt Rolfs, Peter Rothwell, Danish Saleheen, Sudha Seshadri, Pankaj Sharma, Cathie Sudlow, Bradford Worrall, METASTROKE Consortium of the ISGC, WTCCC-2 Consortium, O Colin Stine, Steven J Kittner, Braxton D Mitchell

Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0206554 (2018)

Background and purposePolymorphisms in coagulation genes have been associated with early-onset ischemic stroke. Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C system (TH

Externí odkaz: https://doaj.org/article/d7e9695d35ae48c8af23ab47b2c3c8b2

Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells

Autor: Silvia La Monica, Angela Marcianti, Daniela Lisini, Costanza Lagrasta, Giulio Alessandri, Francesca Paino, Roberta Alfieri, Augusto Pessina, Caterina Frati, Angela Falco, Aldo Bruno Giannì, Lorenzo Spaggiari, Lisa Flammini, Denise Madeddu, Mara Bonelli, Valentina Coccè, Giampietro Farronato, Eugenio Parati, Francesco Petrella

Publikováno v: Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1427, p 1427 (2021)

Background: Malignant Pleural Mesothelioma (MPM) is an aggressive tumor that has a significant incidence related to asbestos exposure with no effective therapy and poor prognosis. The role of mesenchymal stromal cells (MSCs) in cancer is controversia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854a8337f21da37a170057babb3198b6
https://pubmed.ncbi.nlm.nih.gov/34201002

Paclitaxel Priming of TRAIL Expressing Mesenchymal Stromal Cells (MSCs-TRAIL) Increases Antitumor Efficacy of Their Secretome

Autor: Giampietro Farronato, Gianpietro Bondiolotti, Francesca Paino, Valentina Coccè, Augusto Pessina, Valeria Sordi, Eugenio Parati, Aldo Bruno Giannì, Giulio Alessandri, Francesco Petrella, Francesca Sisto, Loredana Cavicchini, Arianna Bonomi

Publikováno v: Current cancer drug targets.

Background: Adipose tissue-derived MSCs engineered with the tumor necrosis factor- related apoptosis-inducing ligand protein (MSCs-TRAIL) have significant anticancer activity. MSCs, without any genetic modifications, exposed to high doses of chemothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a93767260154b23f9689d701435b5ce
https://pubmed.ncbi.nlm.nih.gov/33200709