Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eugenia Volkova"'
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract Pulmonary arterial hypertension (PAH) is more prevalent in females than males; the causes of this sex difference have not been adequately explored. Gain‐of‐function (GOF) mutations in hypoxia‐inducible factor 2α (HIF2A) lead to PAH an
Externí odkaz:
https://doaj.org/article/31d97831abae4b3caf2516ac6c24b8fb
Autor:
Xin Yi Chan, Eugenia Volkova, Joon Eoh, Rebecca Black, Lilly Fang, Rayyan Gorashi, Jihyun Song, Jing Wang, Morgan B. Elliott, Sebastian F. Barreto-Ortiz, James Chen, Brian L. Lin, Lakshmi Santhanam, Linzhao Cheng, Frank S. Lee, Josef T. Prchal, Sharon Gerecht
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102246- (2021)
Summary: Heterozygous gain-of-function (GOF) mutations of hypoxia-inducible factor 2α (HIF2A), a key hypoxia-sensing regulator, are associated with erythrocytosis, thrombosis, and vascular complications that account for morbidity and mortality of pa
Externí odkaz:
https://doaj.org/article/1f751c4cad744791a3d7349744fbf648
Autor:
Giselle A. Suero-Abreu, G. Praveen Raju, Orlando Aristizábal, Eugenia Volkova, Alexandre Wojcinski, Edward J. Houston, Diane Pham, Kamila U. Szulc, Daniel Colon, Alexandra L. Joyner, Daniel H. Turnbull
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 12, Pp 993-1006 (2014)
Mouse models have increased our understanding of the pathogenesis of medulloblastoma (MB), the most common malignant pediatric brain tumor that often forms in the cerebellum. A major goal of ongoing research is to better understand the early stages o
Externí odkaz:
https://doaj.org/article/cc285388a4fa421f9987def3ca0812f4
Autor:
Mathilde Guerbois, Eugenia Volkova, Naomi L Forrester, Shannan L Rossi, Ilya Frolov, Scott C Weaver
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2197 (2013)
The live-attenuated TC-83 strain is the only licensed veterinary vaccine available to protect equids against Venezuelan equine encephalitis virus (VEEV) and to protect humans indirectly by preventing equine amplification. However, TC-83 is reactogeni
Externí odkaz:
https://doaj.org/article/eb411ff989ac404faab9d37fb11bb826
Publikováno v:
Bioengineering & Translational Medicine. 8
Autor:
Rayyan Gorashi, Lilly Fang, Morgan B. Elliott, Joon Eoh, Josef T. Prchal, Jing Wang, Brian L. Lin, James K. Chen, Rebecca Black, Jihyun Song, Sharon Gerecht, Lakshmi Santhanam, Eugenia Volkova, Frank S. Lee, Linzhao Cheng, Xin Yi Chan, Sebastian F. Barreto-Ortiz
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102246-(2021)
iScience
iScience
Summary Heterozygous gain-of-function (GOF) mutations of hypoxia-inducible factor 2α (HIF2A), a key hypoxia-sensing regulator, are associated with erythrocytosis, thrombosis, and vascular complications that account for morbidity and mortality of pat
Publikováno v:
Adv Drug Deliv Rev
In recent years, as the mechanisms of vasculogenesis and angiogenesis have been uncovered, the functions of various pro-angiogenic growth factors (GFs) and cytokines have been identified. Therefore, therapeutic angiogenesis, by delivery of GFs, has b
Autor:
Josef T. Prchal, Rayyan Gorashi, Linzhao Cheng, Morgan B. Elliott, Frank S. Lee, Joon Eoh, Xin Chan, Sharon Gerecht, James K. Chen, Rebecca Black, Lilly Fang, Jing Wang, Sebastian F. Barreto-Ortiz, Jihyun Song, Lakshmi Santhanam, Eugenia Volkova, Brian L. Lin
Publikováno v:
SSRN Electronic Journal.
Heterozygous gain-of-function (GOF) mutations of hypoxia-inducible factor 2α (HIF2A), a significant regulator of hypoxia sensing, are associated with erythrocytosis, thrombosis and vascular complications that account for morbidity and mortality of p
Autor:
Michael D. Taylor, Daniel Stephen, Alexandra L. Joyner, Reeti Mayur Sanghrajka, Marc Remke, Daniel H. Turnbull, Eugenia Volkova, Andrey Korshunov, I-Li Tan, Zhimin Lao, Harikrishna Rallapalli, Alexandre Wojcinski
Publikováno v:
Proceedings of the National Academy of Sciences. 115:3392-3397
The main cell of origin of the Sonic hedgehog (SHH) subgroup of medulloblastoma (MB) is granule cell precursors (GCPs), a SHH-dependent transient amplifying population in the developing cerebellum. SHH-MBs can be further subdivided based on molecular