Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Eugenia T. E. Hong"'
Autor:
Fai Tsang, Katherine C. M. Chew, Yee Kit Tai, Tuck Wah Soong, Eugenia T. E. Hong, Kah-Leong Lim, A.B.M.A. Asad, Kai-Hsiang Chuang, Eng-Tat Ang, Bryce W.Q. Tan, Bing Han Chai, Chengwu Zhang
Publikováno v:
Neuromolecular Medicine
Exposure to divalent metals such as iron and manganese is thought to increase the risk for Parkinson’s disease (PD). Under normal circumstances, cellular iron and manganese uptake is regulated by the divalent metal transporter 1 (DMT1). Accordingly
Autor:
Chee-Hoe Ng, Henry Basil Adeline, Chengwu Zhang, Eugenia T. E. Hong, Bing Han Chai, Kah-Leong Lim
Publikováno v:
Neurodegenerative Diseases. 16:304-316
Mutations of parkin are a prevalent genetic contributor to familial Parkinson's disease (PD). As a key regulator of protein and mitochondrial homeostasis, parkin plays a pivotal role in maintaining dopaminergic neuronal survival. However, whereas Dro