Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eugenia Petoukhov"'
Autor:
Niels H Skotte, Amber L Southwell, Michael E Østergaard, Jeffrey B Carroll, Simon C Warby, Crystal N Doty, Eugenia Petoukhov, Kuljeet Vaid, Holly Kordasiewicz, Andrew T Watt, Susan M Freier, Gene Hung, Punit P Seth, C Frank Bennett, Eric E Swayze, Michael R Hayden
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107434 (2014)
Huntington disease (HD) is an inherited, fatal neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin gene. The mutant protein causes neuronal dysfunction and degeneration resulting in motor dysfunction, cognitive decline, and
Externí odkaz:
https://doaj.org/article/df087f84149f4dfba0bfc4bdc1b0f552
Autor:
Holly Kordasiewicz, Michael R. Hayden, Clarence Frank Bennett, Crystal N. Doty, Erika B. Villanueva, Punit P. Seth, Kuljeet Vaid, Susan M. Freier, Niels H. Skotte, Eugenia Petoukhov, Amber L. Southwell, Jeffrey B. Carroll, Michael E. Østergaard, Eric E. Swayze, Andrew T. Watt, Yuanyun Xie
Publikováno v:
Molecular Therapy. 22:2093-2106
Huntington disease (HD) is a dominant, genetic neurodegenerative disease characterized by progressive loss of voluntary motor control, psychiatric disturbance, and cognitive decline, for which there is currently no disease-modifying therapy. HD is ca
Autor:
Chantal L A Brideau, Mandy L Serran, Dmitry Klokov, Eugenia Petoukhov, Yvonne Devantier, Rebecca R Mantha, Laura A Bannister
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 9, p 1548 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 9; Pages: 1548
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 9; Pages: 1548
International Journal of Molecular Sciences
Enhanced cellular DNA repair efficiency and suppression of genomic instability have been proposed as mechanisms underlying radio-adaptive responses following low-dose radiation exposures. We previously showed that low-dose γ irradiation does not gen
Autor:
Crystal N. Doty, Diepiriye G. Iworima, Niels H. Skotte, Daphne Cheung, Mahmoud A. Pouladi, Ramy A. Slama, Xiaofeng Gu, X. William Yang, Jolene Ooi, Hailey Findlay-Black, Louisa Dal Cengio, Erika B. Villanueva, Michael E. Østergaard, Michael R. Hayden, Holly Kordasiewicz, Eric E. Swayze, Sabine Waltl, Chris Kay, Amber L. Southwell, Eugenia Petoukhov, Yuanyun Xie, Punit P. Seth
Publikováno v:
Human Molecular Genetics. :ddx021
Huntington disease (HD) is a neurodegenerative disease caused by a mutation in the huntingtin (HTT) gene. HTT is a large protein, interacts with many partners and is involved in many cellular pathways, which are perturbed in HD. Therapies targeting H
Publikováno v:
Radiation research. 181(5)
In this study, we sought to determine whether low-dose ionizing radiation, previously shown to induce a systemic adaptive response in C57BL/6J mice, is capable of enhancing the rate of DNA double-strand break repair. Repair capacity was determined by
Autor:
Gene Hung, Michael E. Østergaard, Crystal N. Doty, Eugenia Petoukhov, Kuljeet Vaid, Jeffrey B. Carroll, Andrew T. Watt, C. Frank Bennett, Amber L. Southwell, Michael R. Hayden, Holly Kordasiewicz, Simon C. Warby, Punit P. Seth, Niels H. Skotte, Susan M. Freier, Eric E. Swayze
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107434 (2014)
PLoS ONE
PLoS ONE
Huntington disease (HD) is an inherited, fatal neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin gene. The mutant protein causes neuronal dysfunction and degeneration resulting in motor dysfunction, cognitive decline, and
Autor:
Sarah Fernando, Michael A. Silverman, Shernaz X. Bamji, Farhan Shivji, Diana Hunter, Eugenia Petoukhov, Fergil Mills, Charles Krieger
Publikováno v:
Journal of Cell Science.
The secreted growth factor progranulin (PGRN) has been shown to be important for regulating neuronal survival and outgrowth, as well as synapse formation and function. Mutations in the PGRN gene that result in PGRN haploinsufficiency have been identi