Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eugenia N. Olsufyeva"'
Publikováno v:
Current Topics in Medicinal Chemistry. 17
Introduction The increased resistance of glycopeptide based antibiotics has become a serious problem for the chemotherapy of infections triggered by resistant Gram-positive bacteria. This has motivated the urgent sincere efforts to develop potent gly
Autor:
Victor B Zbarsky, Alexander M. Vinogradov, Maria N. Preobrazhenskaya, Eugeniy E Bykov, Lyubov G. Dezhenkova, M. I. Reznikova, Nikita A. Durandin, Eugenia N. Olsufyeva, Vladimir A. Kuzmin, Alexander A. Shtil, Anna N. Tevyashova
Publikováno v:
The Journal of Antibiotics. 66:523-530
A series of olivomycin A derivatives containing different combinations of the acyl residues in the carbohydrate chains was obtained. The formation of complexes of Mg(2+)-coordinated dimers of these compounds with double-stranded DNA was studied using
Autor:
Nikita A. Durandin, M. I. Reznikova, Eugenia N. Olsufyeva, Vladimir M. Bukhman, Alexander A. Shtil, Vladimir A. Kuzmin, Maria N. Preobrazhenskaya, Lyubov G. Dezhenkova, Anna N. Tevyashova, Yury N. Luzikov, Elena B. Isakova, Alexander M. Vinogradov
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:7387-7393
A novel way of chemical modification of the antibiotic olivomycin A (1) at the side chain of the aglycon moiety was developed. Interaction of olivomycin A with the sodium periodate produced the key acid derivative olivomycin SA (2) in 86% yield. This
Autor:
Susan Obeid, David Durantel, Johan Neyts, Svetlana S. Printsevskaya, Eugenia N. Olsufyeva, Maria N. Preobrazhenskaya, Kai Dallmeier, Fabien Zoulim, Jan Paeshuyse
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Some semi-synthetic derivatives of glycopeptide antibiotics have been shown to exert in vitro antiviral activity against HIV and coronaviruses. Here we report and characterize the in vitro anti-hepatitis C virus (HCV) activity of several s
Autor:
Maria N. Preobrazhenskaya, Tatiana V. Burova, V. Ya. Grinberg, Alexander M. Vinogradov, Vladimir A. Kuzmin, E. V. Andreeva, S. G. Skuridin, Eugenia N. Olsufyeva, Anna N. Tevyashova, Natalia V. Grinberg, Alexander A. Shtil
Publikováno v:
Doklady Biochemistry and Biophysics. 435:334-338
Autor:
Jan Balzarini, Eugenyi E. Bykov, Maria N. Preobrazhenskaya, Eugenia N. Olsufyeva, Lyubov G. Dezhenkova, Alexander A. Shtil, Konstantin F. Turchin, Anna N. Tevyashova
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:4961-4967
The azo coupling of the antibiotic olivomycin I (1) with aryl diazonium tetrafluoroborates produced 5-aryldiazenyl-6-O-deglycosyl derivatives of 1. The structures of new compounds were confirmed by (1)H NMR and mass spectrometry analysis. A quantum-c
Autor:
Anna N, Tevyashova, Eugenia N, Olsufyeva, Eugenia N, Zbarsky, Jan, Balzarini, Alexander A, Shtil, Lyubov G, Dezhenkova, Vladimir M, Bukhman, Victor B, Zbarsky, Maria N, Preobrazhenskaya
Publikováno v:
The Journal of Antibiotics. 62:37-41
A novel way of chemical modification of the antibiotic olivomycin I at the 2'-keto group of the side chain of the aglycone moiety was developed. Reaction of olivomycin I with the carboxymethoxylamine hemihydrochloride gave the key intermediate, 2'-ca
Publikováno v:
Expert Opinion on Therapeutic Patents. 14:141-173
The review summarises patents claiming novel glycopeptides of vancomycin and teicoplanin families published from January 1999 to June 2003. A brief overview of the structures of the most important natural antibacterial glycopeptides, the mode of acti
Autor:
Eugenia N. Olsufyeva, Alexander A. Shtil, Valeria S. Simonova, Anna N. Tevyashova, Maria N. Preobrazhenskaya, A. V. Samusenko
Publikováno v:
The Journal of Antibiotics. 57:143-150
The new hydrophilic derivatives of 14-hydroxycarminomycin were obtained using 13-dimethyl ketal of 14-bromocarminomycin (6) as the starting compound. The reductive alkylation of 6 with melibiose or D-galactose followed by hydrolysis of the correspond
Autor:
Anatole Klyosov, Eugenia N. Olsufyeva, Anna N. Tevyashova, David Platt, Maria N. Preobrazhenskaya, Ivan D. Trestchalin
Publikováno v:
Carbohydrate Research. 338:1359-1367
A general scheme of synthesis of antibiotic doxorubicin derivatives is based on the 13-dimethyl ketal of 14-bromodaunorubicin ( 4 ). The interaction of 4 with melibiose ( 5 ), lactose ( 6 ), 3-methoxy-4- O -(2,3,4,6-tetra- O -acetyl-β- d -galactopyr