CRAMP deficiency leads to a pro-inflammatory phenotype and impaired phagocytosis after exposure to bacterial meningitis pathogens

Autor: Eugenia Kress, Julika Merres, Lea-Jessica Albrecht, Sven Hammerschmidt, Thomas Pufe, Simone C. Tauber, Lars-Ove Brandenburg

Publikováno v: Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-15 (2017)

Abstract Background Antimicrobial peptides are important components of the host defence with a broad range of functions including direct antimicrobial activity and modulation of inflammation. Lack of cathelin-related antimicrobial peptide (CRAMP) was

Externí odkaz: https://doaj.org/article/947be4f944f5420a862871de13a5874e

Toll-Like Receptor 2-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination

Autor: Eugenia Kress, Kai Bihler, Tim Clarner, Simone C. Tauber, Lars-Ove Brandenburg, Stefan Esser, Thomas Pufe, Markus Kipp, Matthias B. Stope, Stella Nyamoya, Larissa Göpfrich

Publikováno v: Molecular Neurobiology. 55:6237-6249

Multiple sclerosis (MS) is a chronic degenerative disease of the central nervous system that is characterized by myelin abnormalities, oligodendrocyte pathology, and concomitant glia activation. The factors triggering gliosis and demyelination are cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec30b79bfc36fdf0a2c12d5d7cb92a0
https://doi.org/10.1007/s12035-017-0838-2

Psoriasin has divergent effects on the innate immune responses of murine glial cells

Autor: Ronald Wolf, Sandra Jansen, Eugenia Kress, Thomas Pufe, Christoph Jan Wruck, Matthias Michalek, Athanassios Fragoulis, Simone C. Tauber, Joachim Grötzinger, Lars-Ove Brandenburg

Publikováno v: Journal of Neurochemistry. 141:86-99

Antimicrobial peptides (AMP) are an important part of the innate immune defense in the central nervous system (CNS). The expression of the AMP psoriasin (S100A7) is up-regulated during bacterial meningitis. However, the exact mechanisms induced by ps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99245c2fb1f3c0829a078811490eabf
https://doi.org/10.1111/jnc.13959

Lack of chemokine (C-C motif) ligand 3 leads to decreased survival and reduced immune response after bacterial meningitis

Autor: Nicole Schröder, Vanessa Aust, Matthias B. Stope, Simone C. Tauber, Thomas Pufe, Eugenia Kress, Lars-Ove Brandenburg, Stephanie Abraham, Markus Kipp

Publikováno v: Cytokine. 111

Pneumococcal meningitis, caused by Streptococcus pneumoniae, is the most common type of bacterial meningitis. The clinical management of this disease has been challenged by the emergence of multidrug-resistant Streptococcus pneumoniae, requiring the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58eb2982779e53b7ef29a425542b762a
https://pubmed.ncbi.nlm.nih.gov/30199766

Lack of Proinflammatory Cytokine Interleukin-6 or Tumor Necrosis Factor Receptor-1 Results in a Failure of the Innate Immune Response after Bacterial Meningitis

Autor: Eugenia Kress, Julika Merres, Sandra Jansen, Simone C. Tauber, Lars-Ove Brandenburg, Thomas Pufe, Matthias B. Stope, Lea-Jessica Albrecht

Publikováno v: Mediators of Inflammation
Mediators of inflammation 2016, 7678542 (2016). doi:10.1155/2016/7678542
Mediators of Inflammation, Vol 2016 (2016)

Mediators of inflammation 2016, 7678542 (2016). doi:10.1155/2016/7678542
Published by Hindawi Publishing Corp., Sylvania, Ohio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb0a73dd328b8bce7d7639deb19ade0
http://europepmc.org/articles/PMC4749820