Adult aberrant astrocytes submitted to late passage cultivation lost differentiation markers and decreased their pro-inflammatory profile

Autor: Gabriel Otero, Carmen Bolatto, Eugenia Isasi, Sofía Cerri, Paola Rodríguez, Daniela Boragno, Marta Marco, Cristina Parada, Matías Stancov, María Noel Cuitinho, Silvia Olivera-Bravo

Publikováno v: Heliyon, Vol 10, Iss 9, Pp e30360- (2024)

In amyotrophic lateral sclerosis (ALS), astrocytes are considered key players in some non-cell non-neuronal autonomous mechanisms that underlie motor neuron death. However, it is unknown how much of these deleterious features were permanently acquire

Externí odkaz: https://doaj.org/article/648ccc7ad9d5405db8a32658f34bc2ca

Neuroprotective effects of violacein in a model of inherited amyotrophic lateral sclerosis

Autor: Silvia Olivera-Bravo, Carmen Bolatto, Gabriel Otero Damianovich, Matías Stancov, Sofía Cerri, Paola Rodríguez, Daniela Boragno, Karina Hernández Mir, María Noel Cuitiño, Fernanda Larrambembere, Eugenia Isasi, Diego Alem, Lucía Canclini, Marta Marco, Danilo Davyt, Pablo Díaz-Amarilla

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)

Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive death of motor neurons and muscle atrophy, with defective neuron-glia interplay and emergence of aberrant glial phenotypes having a role in disea

Externí odkaz: https://doaj.org/article/58ea818701054f27ba474053bf262b13

Pericyte Mapping in Cerebral Slices with the Far-red Fluorophore TO-PRO-3

Autor: Sandra Mai-Morente, Juan Irigoyen, Victoria Carriquiry, Virginia Marset, Mariana Di Doménico, Eugenia Isasi, Veronica Abudara

Publikováno v: Bio-Protocol, Vol 11, Iss 22 (2021)

This protocol describes a method for high-resolution confocal imaging of pericytes with the far-red fluorophore TO-PROTM-3 Iodide 642/661 in cerebral slices of murine. Identification of pericytes with TO-PRO-3 is a short time-consuming, high cost-eff

Externí odkaz: https://doaj.org/article/d79976635a3342d5b25501c4bfb3a9ea

The application of artificial gravity in medicine and space

Autor: Eugenia, Isasi, Maria E, Isasi, Jack J W A, van Loon

Publikováno v: Isasi, E, Isasi, M E & van Loon, J J W A 2022, ' The application of artificial gravity in medicine and space ', Frontiers in Physiology, vol. 13, 952723, pp. 1-15 . https://doi.org/10.3389/fphys.2022.952723
Isasi, E, Isasi, M E & van Loon, J J W A 2022, ' The application of artificial gravity in medicine and space ', Frontiers in Physiology, vol. 13, 952723 . https://doi.org/10.3389/fphys.2022.952723

Gravity plays a crucial role in physiology. The lack of gravity, like in long duration spaceflight missions, cause pathologies in e.g., the musculoskeletal system, cardiovascular deconditioning, immune system deprivation or brain abnormalities, to ju

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52efd12a9cbe2270da6b462b05074e6
https://research.vu.nl/en/publications/fa495dbf-4053-46ce-a1bd-5bfbb7578fa6

Pericyte Mapping in Cerebral Slices with the Far-red Fluorophore TO-PRO-3

Autor: Sandra P. Mai-Morente, Verónica Abudara, Juan P. Irigoyen, Eugenia Isasi, Virginia M. Marset, Victoria M. Carriquiry, Mariana Di Doménico

Publikováno v: Bio Protoc

This protocol describes a method for high-resolution confocal imaging of pericytes with the far-red fluorophore TO-PRO(TM)-3 Iodide 642/661 in cerebral slices of murine. Identification of pericytes with TO-PRO-3 is a short time-consuming, high cost-e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d275ec64fe6564d2fc973b17b19cb10c
https://europepmc.org/articles/PMC8635853/