Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eugenia Bifeld"'
Autor:
George E. Magoulas, Pantelis Afroudakis, Kalliopi Georgikopoulou, Marina Roussaki, Chiara Borsari, Theano Fotopoulou, Nuno Santarem, Emile Barrias, Paloma Tejera Nevado, Julia Hachenberg, Eugenia Bifeld, Bernhard Ellinger, Maria Kuzikov, Irini Fragiadaki, Effie Scoulica, Joachim Clos, Sheraz Gul, Maria Paola Costi, Wanderley de Souza, Kyriakos C. Prousis, Anabela Cordeiro da Silva, Theodora Calogeropoulou
Publikováno v:
Molecules, Vol 26, Iss 14, p 4204 (2021)
A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised
Externí odkaz:
https://doaj.org/article/445daea165834b30a0f90e3cf6bb94b0
Autor:
Eugenia Bifeld, Stephan Lorenzen, Katharina Bartsch, Juan-José Vasquez, T. Nicolai Siegel, Joachim Clos
Publikováno v:
mSystems, Vol 3, Iss 6 (2018)
ABSTRACT The 90-kDa heat shock protein (HSP90) of eukaryotes is a highly abundant and essential chaperone required for the maturation of regulatory and signal proteins. In the protozoan parasite Leishmania donovani, causative agent of the fatal visce
Externí odkaz:
https://doaj.org/article/1ab973143c82493abe936cce1c94d13d
Autor:
Marina Roussaki, George E. Magoulas, Theano Fotopoulou, Nuno Santarem, Emile Barrias, Ina Pöhner, Sara Luelmo, Pantelis Afroudakis, Kalliopi Georgikopoulou, Paloma Tejera Nevado, Julia Eick, Eugenia Bifeld, María J. Corral, María Dolores Jiménez-Antón, Bernhard Ellinger, Maria Kuzikov, Irini Fragiadaki, Effie Scoulica, Sheraz Gul, Joachim Clos, Kyriakos C. Prousis, Juan J. Torrado, José María Alunda, Rebecca C. Wade, Wanderley de Souza, Anabela Cordeiro da Silva, Theodora Calogeropoulou
Publikováno v:
Bioorganic Chemistry. 138:106615
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f2d245f1033d6574ef10b0984715fe7
https://doi.org/10.1016/j.bioorg.2023.106615
https://doi.org/10.1016/j.bioorg.2023.106615
Autor:
Irini Fragiadaki, Theodora Calogeropoulou, Sheraz Gul, Chiara Borsari, Wanderley de Souza, Bernhard Ellinger, Paloma Tejera Nevado, Nuno Santarém, Pantelis Afroudakis, Julia Hachenberg, Marina Roussaki, Anabela Cordeiro da Silva, Emile Santos Barrias, Maria Kuzikov, George E. Magoulas, Kalliopi Georgikopoulou, Kyriakos C. Prousis, Theano Fotopoulou, Eugenia Bifeld, Joachim Clos, Effie Scoulica, Maria Paola Costi
Publikováno v:
Molecules, Vol 26, Iss 4204, p 4204 (2021)
Molecules
Volume 26
Issue 14
Molecules
Volume 26
Issue 14
A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206edec9de51996451d8dcbf86e6cd97
https://www.mdpi.com/1420-3049/26/14/4204
https://www.mdpi.com/1420-3049/26/14/4204
Autor:
Marie Groneberg, Joachim Clos, Julie Sellau, Siew Ling Choy, Stefan Hoenow, Nadine Kottmayr, Melina Mühlenpfordt, Hannelore Lotter, Helena Fehling, Frederic Ting, Chris Meier, Claudia Marggraff, Julia Eick, Dirk Landschulze, Sarah Corinna Lender, Eugenia Bifeld, Hannah Bernin
Publikováno v:
Antimicrobial Agents and Chemotherapy. 64
With an estimated number of new cases annually of approximately 1.4 million, leishmaniasis belongs to the most important parasitic diseases in the world. Nevertheless, existing drugs against leishmaniasis in general have several drawbacks that urgent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ca4e1ffa0136bedde26689bbb07245
https://doi.org/10.1128/aac.00161-20
https://doi.org/10.1128/aac.00161-20
Autor:
Helena, Fehling, Siew Ling, Choy, Frederic, Ting, Dirk, Landschulze, Hannah, Bernin, Sarah Corinna, Lender, Melina, Mühlenpfordt, Eugenia, Bifeld, Julia, Eick, Claudia, Marggraff, Nadine, Kottmayr, Marie, Groneberg, Stefan, Hoenow, Julie, Sellau, Joachim, Clos, Chris, Meier, Hannelore, Lotter
Publikováno v:
Antimicrobial Agents and Chemotherapy
With an estimated number of new cases annually of approximately 1.4 million, leishmaniasis belongs to the most important parasitic diseases in the world. Nevertheless, existing drugs against leishmaniasis in general have several drawbacks that urgent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3e96e069a7010ae83893ef438ad5436
https://pubmed.ncbi.nlm.nih.gov/32393489
https://pubmed.ncbi.nlm.nih.gov/32393489
Autor:
Eugenia Bifeld
Publikováno v:
Methods in Molecular Biology ISBN: 9781493992096
Murine bone marrow-derived macrophages (BMMs) can be differentiated within 10 days from ex vivo bone marrow progenitor cells by supplementing the cell growth medium with colony stimulating factor-1 (CSF-1). Mature macrophages express specific myeloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa2429dd12d89c2c87c9d02c0c356fae
https://doi.org/10.1007/978-1-4939-9210-2_12
https://doi.org/10.1007/978-1-4939-9210-2_12
Autor:
Eugenia Bifeld
Publikováno v:
Methods in Molecular Biology ISBN: 9781493992096
While infecting humans and other mammals, Leishmania spp. are obligate intracellular parasites. Therefore, for the purpose of therapeutic intervention and the study of infectivity, the relevant form of Leishmania spp. is the intracellular amastigote.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::571f7d2e2f6687d3a448c82e7a7025f3
https://doi.org/10.1007/978-1-4939-9210-2_13
https://doi.org/10.1007/978-1-4939-9210-2_13
Autor:
Chiara Borsari, Maria Kuzikov, Catarina Baptista, Juan J. Torrado, Joachim Clos, Paloma Tejera Nevado, Maria Paola Costi, José María Alunda, Eugenia Bifeld, María Dolores Jiménez-Antón, Julia Eick, Caio Haddad Franco, Dorothea Zander-Dinse, Jeanette Reinshagen, Pasquale Linciano, Annalisa Tait, Nuno Santarém, María Jesús Corral, Gesa Witt, Luca Costantino, Glauco Ponterini, Rosaria Luciani, Anabela Cordeiro-da-Silva, Markus Wolf, Leda Severi, Carolina B. Moraes, Ana Isabel Olías-Molero, Sheraz Gul, Bernhard Ellinger, Stefania Ferrari
Leishmaniasis, a major health problem worldwide, has a limited arsenal of drugs for its control. The appearance of resistance to first- and second-line anti-leishmanial drugs confirms the need to develop new and less toxic drugs that overcome spontan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b38f72f55d16bf830aa39813bbeeb1
https://publica.fraunhofer.de/handle/publica/262302
https://publica.fraunhofer.de/handle/publica/262302
Autor:
Paloma Tejera Nevado, Anabela Cordeiro-da-Silva, María Jesús Corral, Gesa Witt, Catarina Baptista, Rebecca C. Wade, G. Landi, José Mª Alunda, Juan J. Torrado, Bernhard Ellinger, Maria Kuzikov, Maria Paola Costi, Julia Eick, Stefano Mangani, Jeanette Reinshagen, Eugenia Bifeld, Nuno Santarém, Sheraz Gul, Manfred Kohler, Stefania Ferrari, Joachim Clos, María Dolores Jiménez-Antón, Lucia Dello Iacono, Birte Behrens, Philip Gribbon, Cecilia Pozzi, Oliver Keminer, Markus Wolf, Luca Costantino, Stefan Henrich, Matteo Trande, Rosaria Luciani, Ina Poehner, Flavio Di Pisa, Annalisa Tait, Federica Pellati, Chiara Borsari
Publikováno v:
'Journal of Medicinal Chemistry ', vol: 59, pages: 7598-7616 (2016)
Flavonoids represent a potential source of new antitrypanosomatidic leads. Starting from a library of natural products, we combined target-based screening on pteridine reductase 1 with phenotypic screening on Trypanosoma brucei for hit identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a889fd44ef2bdd1456774dc95d126ca2
https://doi.org/10.1021/acs.jmedchem.6b00698
https://doi.org/10.1021/acs.jmedchem.6b00698