A truncating mutation in the laminin-332α chain highlights the role of the LG45 proteolytic domain in regulating keratinocyte adhesion and migration

Autor: Daniele Castiglia, M. El Hachem, Eugenia Piccinni, Giovanna Zambruno, Renata Boldrini, Paola Fortugno, Valentina Calabresi, Andrea Diociaiuti, Francesca Cianfarani, G. Di Zenzo

Publikováno v: British Journal of Dermatology. 170:1056-1064

Summary Background Altered function of laminin-332 (α3β3γ2) consequent to mutations in the LAMA3, LAMB3 and LAMC2 genes causes junctional epidermolysis bullosa non-Herlitz (JEB-nH). JEB-nH patients suffer from skin blistering and have an increased

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9578aea55f0c970728dd912d1260d647
https://doi.org/10.1111/bjd.12816

Induction of senescence pathways in Kindler syndrome primary keratinocytes

Autor: Riccardo Maurelli, Massimo Teson, Daniele Castiglia, Cristina Has, Elena Dellambra, Eugenia Piccinni, Giovanna Zambruno, G. Di Zenzo

Publikováno v: British Journal of Dermatology. 168:1019-1026

Summary Background Individuals with Kindler syndrome (KS) have loss-of-function mutations in the FERMT1 gene that encodes the focal adhesion component kindlin-1. The major clinical manifestation of KS is epidermal atrophy (premature skin ageing). Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d608623a252d62585bc20a32134cfe58
https://doi.org/10.1111/bjd.12184

The bromodomain-containing protein Bdf1p acts as a phenotypic and transcriptional multicopy suppressor of YAF9 deletion in yeast

Autor: Laura Frontali, Cristina Mazzoni, Antonella Cavalli, Giovanna Costanzo, Joanna Rytka, Francesca Ciceroni, Anna Chelstowska, Eugenia Piccinni, Piotr P. Slonimski, Michele M. Bianchi, Rodolfo Negri, Dorota Grabowska

Publikováno v: Molecular Microbiology. 53:953-968

Summary It was observed previously that the deletion of the open reading frame YNL107w ( YAF 9) was highly pleio- tropic in yeast and caused defective growth pheno- types in the presence of several unrelated inhibitors, including caesium chloride. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6057ac18648c38cbb55858e3d8c6471e
https://doi.org/10.1111/j.1365-2958.2004.04184.x

MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines

Autor: Lauretta, Levati, Elena, Pagani, Sveva, Romani, Daniele, Castiglia, Eugenia, Piccinni, Claudia, Covaciu, Patrizia, Caporaso, Sergio, Bondanza, Francesca R, Antonetti, Enzo, Bonmassar, Fabio, Martelli, Ester, Alvino, Stefania, D'Atri

Publikováno v: Pigment cell & melanoma research
(2011).
info:cnr-pdr/source/autori:Lauretta Levati, Elena Pagani, Sveva Romani, Daniele Castiglia, Eugenia Piccinni, Claudia Covaciu, Patrizia Caporaso, Sergio Bondanza, Francesca Romana Antonetti, Enzo Bonmassar, Fabio Martelli, Ester Alvino and Stefania D’Atri/titolo:MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines/doi:/rivista:Pigment cell & melanoma research (Print)/anno:2011/pagina_da:/pagina_a:/intervallo_pagine:/volume
24 (2011): 538–550. doi:10.1111/j.1755-148X.2011.00857.x
info:cnr-pdr/source/autori:Levati, Lauretta; Pagani, Elena; Romani, Sveva; Castiglia, Daniele; Piccinni, Eugenia; Covaciu, Claudia; Caporaso, Patrizia; Bondanza, Sergio; Antonetti, Francesca R.; Bonmassar, Enzo; Martelli, Fabio; Alvino, Ester; D'Atri, Stefania/titolo:MicroRNA-155 targets the SKI gene in human melanoma cell lines/doi:10.1111%2Fj.1755-148X.2011.00857.x/rivista:Pigment cell & melanoma research (Print)/anno:2011/pagina_da:538/pagina_a:550/intervallo_pagine:538–550/volume:24

P>The SKI protein is a transcriptional coregulator over-expressed in melanoma. Experimentally induced down-regulation of SKI inhibits melanoma cell growth in vitro and in vivo. MicroRNAs (miRNAs) negatively modulate gene expression and have been impl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e80a57123bb317f3af9ff12aa93b5d5
https://publications.cnr.it/doc/59190

The bromodomain-containing protein Bdf1p acts as a phenotypic and transcriptional multicopy suppressor of YAF9 deletion in yeast

Autor: Michele M, Bianchi, Giovanna, Costanzo, Anna, Chelstowska, Dorota, Grabowska, Cristina, Mazzoni, Eugenia, Piccinni, Antonella, Cavalli, Francesca, Ciceroni, Joanna, Rytka, Piotr P, Slonimski, Laura, Frontali, Rodolfo, Negri

It was observed previously that the deletion of the open reading frame YNL107w (YAF9) was highly pleiotropic in yeast and caused defective growth phenotypes in the presence of several unrelated inhibitors, including caesium chloride. We have selected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5842c2383c92f758c4912f53cea64f5b
http://hdl.handle.net/11573/363635