Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eugeni Namsaraev"'
Autor:
Arkady Khodursky, Mitsu Reddy, Tiffany Brund, Maneesh Jain, Eugeni Namsaraev, Carrie Haverty, Morten Rasmussen
Publikováno v:
American Journal of Obstetrics and Gynecology. 228:S372-S373
Autor:
Joan Camunas-Soler, Elaine P.S. Gee, Mitsu Reddy, Jia Dai Mi, Mainou Thao, Tiffany Brundage, Farooq Siddiqui, Natasha L. Hezelgrave, Andrew H. Shennan, Eugeni Namsaraev, Carrie Haverty, Maneesh Jain, Michal A. Elovitz, Morten Rasmussen, Rachel M. Tribe
Publikováno v:
American journal of obstetrics and gynecology. 227(1)
Spontaneous preterm birth remains the main driver of childhood morbidity and mortality. Because of an incomplete understanding of the molecular pathways that result in spontaneous preterm birth, accurate predictive markers and target therapeutics rem
Autor:
Eugeni Namsaraev, Paul Berg
Publikováno v:
Journal of Biological Chemistry. 275:3970-3976
The Rad51 protein of Saccharomyces cerevisiae, like its bacterial counterpart RecA, promotes strand exchange between circular single-stranded DNA (ssDNA) and linear double-stranded DNA (dsDNA) in vitro. However, the two proteins differ in the require
Autor:
Paul Berg, Eugeni Namsaraev
Publikováno v:
Biochemistry. 37:11932-11939
The presumptive first step in the Rad51-promoted formation of joint molecules is binding of the protein to ssDNA in the presence of ATP and Mg2+. In this paper, we report that Rad51's ability to bind DNA is rapidly inactivated when incubated at 30-37
Autor:
Eugeni Namsaraev, Paul Berg
Publikováno v:
Journal of Biological Chemistry. 273:6177-6182
Like RecA, Saccharomyces cerevisiae Rad51p promotes strand exchange between circular single-stranded DNA (ssDNA) and linear double-stranded DNA (dsDNA). We have investigated several parameters characteristic of the interaction of Rad51p with ssDNA an
Autor:
Paul Berg, Eugeni Namsaraev
Publikováno v:
Molecular and Cellular Biology. 17:5359-5368
The Saccharomyces cerevisiae RAD51 gene product takes part in genetic recombination and repair of DNA double strand breaks. Rad51, like Escherichia coli RecA, catalyzes strand exchange between homologous circular single-stranded DNA (ssDNA) and linea
Autor:
William J. Mileski, Rachel Kasinskas, Jonathan Schultz, Mohammad Alanjary, Jacqueline A. Fidanza, Bernard P. Puc, G. Thomas Roth, Annika Branting, Yutao Fu, John H. Leamon, Marina Sedova, Travis A. Clark, Tanya Sokolsky, Michael R. Lyons, Simon Cawley, Wolfgang Hinz, Alan Williams, Matthew D. Edwards, Xin Miao, John F. Davidson, Kevin McKernan, Jeremy Hoon, Eugeni Namsaraev, James Bustillo, Jan Fredrik Simons, Todd Rearick, Eileen T. Dimalanta, Isaac B. Stoner, Jonathan M. Rothberg, Erika Feierstein, David Marran, Jeffrey T. Branciforte, Devin Dressman, Mark James Milgrew, John Nobile, David Light, Martin Huber, Nils Homer, Michelle Schorn, Melville Davey, Brian Reed, Kim L. Johnson, Jeffrey Sabina, Jason W. Myers
Publikováno v:
Nature. 475(7356)
The seminal importance of DNA sequencing to the life sciences, biotechnology and medicine has driven the search for more scalable and lower-cost solutions. Here we describe a DNA sequencing technology in which scalable, low-cost semiconductor manufac
Autor:
Heather Brummel McCuen, Marvin H. Caruthers, Emily M LeProust, Eugeni Namsaraev, Bridget Moore, Bill J. Peck, Konstantin S. Spirin
Publikováno v:
Nucleic Acids Research
We have achieved the ability to synthesize thousands of unique, long oligonucleotides (150mers) in fmol amounts using parallel synthesis of DNA on microarrays. The sequence accuracy of the oligonucleotides in such large-scale syntheses has been limit
Autor:
Zhiyong Wang, Jianbiao Zheng, Albert B. Seymour, Adam Pavlicek, Steven Bentivegna, Malek Faham, Martin Moorhead, Eugeni Namsaraev, Kent Suyenaga, Victoria Carlton, Thomas D. Willis, Liana Lee, James S. Ireland, Farooq Siddiqui
Publikováno v:
Human mutation. 29(3)
Mismatch repair detection (MRD) was used to screen 93 matched tumor-normal sample pairs and 22 cell lines for somatic mutations in 30 cancer relevant genes. Using a starting amount of only 150 ng of genomic DNA, we screened 102 kb of sequence for som
Autor:
Eunice Prakash, Andrew Boudreau, Ronald W. Davis, Tiffany Brundage, Hywel B. Jones, Paul Hardenbol, Maneesh Jain, Oleg Iartchouk, Fuli Yu, Ron Fitzgerald, Xin Miao, Sy Ghose, Richard A. Gibbs, Eugeni Namsaraev, Xiuhua Lu, George Karlin-Neumann, Karen Tran, Ayca Erbilgin, Carsten Bruckner, Zhiyong Wang, Jim Eberle, Steve Chow, Jennifer MacKenzie, Bridget Moore, Martin Moorhead, Mat Falkowski, John W. Belmont, Shiran Pasternak, Thomas D. Willis
Publikováno v:
Genome research. 15(2)
Complex human diseases are known to have a significant genetic component. Despite some important successes (Altshuler et al. 2000; Hugot et al. 2001), the elucidation of the underlying genetic determinants have proven resistant to standard methods. L