Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Eugene Zhukovsky"'
Autor:
Shangzi Wang, Elana J Fertig, Allison A Fitzgerald, Veena Agarwal, Emily F Marcisak, Annie Zuo, Sandra A Jablonski, Melanie Loth, John MacDougall, Eugene Zhukovsky, Shubhendu Trivedi, Dimple Bhatia, Vince O'Neill, Louis M Weiner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/0ee773f945a04c99afce61314f31fcd8
Autor:
Simon Edward Plyte, Marie Fraudeau, Jonathan Grivel, Paloma Hougron, Katja Klausz, Dorothee Winterberg, Britta von Below, Alexandre Ivagnes, Claire Germain, Sebastian Amigorena, Eugene Zhukovsky, Matthias Peipp, Pierre-Emmanuel Gerard, Olivier Lantz, Julie Prigent
Publikováno v:
Cancer Research. 83:2954-2954
Background: Mucosal-Associated Invariant T cells (MAITs) are an abundant subset of non-conventional T-cells with potent cytotoxic capacity (up to 20% of circulating T-cells) that are naturally resident in many tissues and solid tumors. T-cell redirec
Autor:
Maria Pihlgren, Olivia Hall, Laura Carretero, Carole Estoppey, Adam Drake, Daniela Pais, Jeremy Loyau, Jeremy Berret, Isabelle Gruber, Perrine Suere, Vincent Schnorhk, Emilie Nallet, Blandine Pouleau, Myriam Chimen, Julie Macoin, Elodie Stainnack, Thierry Monney, Aurore Delachat, Cyrille Dreyfus, Thomas Matthes, Cyril Konto, Michael Dyson, Stanislas Blein, Lamine Mbow, Rebecca Wood, Ankita Srivastava, Eugene Zhukovsky, Mario Perro
Publikováno v:
Blood. 140:858-859
Autor:
Sammicheli Stefano, Camille Grandclement, Valentina Labanca, Stefania De Angelis, Carole Estoppey, Myriam Chimen, Blandine Pouleau, Perrine Suere, Emilie Nallet, Ankita Srivastava, Eric J. Feldman, Igor Proscurshim, Cyril Konto, Eugene Zhukovsky, Mario Perro
Publikováno v:
Blood. 140:6237-6238
Autor:
Leo Rasche, Uwe Reusch, Margarete Karg, Johannes Duell, Eugene Zhukovsky, Dragana S Lukic, Max S. Topp, Florian Eisele, Martin Treder, Erich Rajkovic, Hermann Einsele, Joachim Koch
Publikováno v:
Journal of Immunotherapy. 42:180-188
Immunotherapy of B-cell malignancies with bispecific antibodies is an emerging treatment option. However, not all patients benefit from these therapies, presumably due to pretreatment regimens. Therefore, we determined the effect of different treatme
Publikováno v:
Cancer Research. 82:5611-5611
TGFβ is a secreted protein produced by tumors that promotes cancer progression primarily via the suppression of both the innate and adaptive immune systems. This makes TGFβ a promising immunotherapeutic target in cancer. It is ubiquitously expresse
Autor:
shubhendu Trivedi, Sandra A. Jablonski, Elana J. Fertig, Vince O'Neill, Allison A. Fitzgerald, Louis M. Weiner, Shangzi Wang, Melanie Loth, Veena R Agarwal, Eugene Zhukovsky, Emily F Marcisak, John MacDougall, Annie Zuo, Dimple Bhatia
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundPancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer death in the USA by 2030. Immune checkpoint inhibitors fail to control most PDAC tumors because of PDAC’s extensive immunosuppressive microenvir
Autor:
James Edward Ackroyd, Chander Peddaboina, Eugene Zhukovsky, Arnima Bisht, Lindsey Hudson, San Lin Lou, Robert Boyd, Abderrahim Fandi, Livija Deban, Martin Barnes, Angelo Kaplan, Christian Rohlff, Murray Cox, Jason D. Allen, Nickolas Attanasio
Publikováno v:
Cancer Research. 80:5167-5167
Identification of novel targets in cancer immunotherapy is needed to address the significant number of patients that either do not respond to current therapies or encounter unacceptable toxicities. The first two generations of immuno-oncology drugs h
Autor:
Martin Treder, Michael Weichel, Kristina Ellwanger, Michael Tesar, Eugene Zhukovsky, Stefan Knackmuss, Vera Molkenthin, Ivica Fucek, Thorsten Gantke, Uwe Reusch
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Frontiers in Oncology
Frontiers in Oncology
To harness the cytotoxic capacity of immune cells for the treatment of solid tumors, we developed tetravalent, bispecific tandem diabody (TandAb) antibodies that recognize EGFRvIII, the deletion variant III of the epidermal growth factor receptor (EG
Autor:
Stefan Knackmuss, Sergej Kiprijanov, Carmen Burkhardt, Uwe Reusch, Eugene Zhukovsky, Ivica Fucek, Karin Hoffmann, Fabrice Le Gall, Melvyn Little, Mikaelle Le Gall
Publikováno v:
mAbs
To improve recruitment and activation of natural killer (NK) cells to lyse tumor cells, we isolated a human anti-CD16A antibody with similar affinity for the CD16A 158F/V allotypes, but no binding to the CD16B isoform. Using CD16A-targeting Fv domain