Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Eugene Y Chiang"'
Autor:
Yan Qu, Ira Mellman, Ellen Duong, Thomas D Wu, Eugene Y Chiang, Katherine Nutsch, Karl L Banta, Charles W Tran, Stephanie Mittman, Barzin Y Nabet, Namrata S Patil
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/5a68ddaf764c4d40afd06e0a458c6d04
Autor:
Ira Mellman, Eugene Y Chiang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/2b6e0c9ae3b843b6bb9238b299b7f508
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180154 (2017)
Ion channels regulate a variety of physiological processes and represent an important class of drug target. Among the many methods of studying ion channel function, patch clamp electrophysiology is considered the gold standard by providing the ultima
Externí odkaz:
https://doaj.org/article/ef68edb4cf624a2ea96e09142c796ffa
Autor:
Rajbharan Yadav, Suzanne Schubbert, Patrick G. Holder, Eugene Y. Chiang, Nargess Kiabi, Liz Bogaert, Irene Leung, Rumana Rashid, Kendra N. Avery, Christine Bonzon, John R. Desjarlais, Shomyseh Sanjabi, Amy Sharma, Michelle Lepherd, Amy Shelton, Pam Chan, Yanqiu Liu, Louis Joslyn, Iraj Hosseini, Eric G. Stefanich, Amrita V. Kamath, Matthew J. Bernett, Vittal Shivva
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionInterleukin 15 (IL-15) is a potential anticancer agent and numerous engineered IL-15 agonists are currently under clinical investigation. Selective targeting of IL-15 to specific lymphocytes may enhance therapeutic effects while helping t
Externí odkaz:
https://doaj.org/article/31030b79b4034614806d2f9e04a075ba
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83457 (2013)
Epstein-Barr virus induced receptor 2 (EBI2), a Gαi-coupled G protein-coupled receptor, is a chemotactic receptor for B, T and dendritic cells (DC). Genetic studies have also implicated EBI2 as a regulator of an interferon regulatory factor 7 (IRF7)
Externí odkaz:
https://doaj.org/article/dae4ec9125314ff48442f1cf9a32929c
Autor:
Eugene Y Chiang, Ganesh Kolumam, Krista M McCutcheon, Judy Young, Zhonghua Lin, Mercedesz Balazs, Jane L Grogan
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33106 (2012)
Graft-versus-host disease (GVHD) is a major barrier to successful allogeneic hematopoietic cell transplantation and is largely mediated by activated donor lymphocytes. Lymphotoxin (LT)-α is expressed by subsets of activated T and B cells, and studie
Externí odkaz:
https://doaj.org/article/8101721c42674a4b9246b59128b49823
Autor:
Eugene Y Chiang, Ira Mellman
Publikováno v:
Journal for immunotherapy of cancer. 10(4)
Recent advances in understanding the roles of immune checkpoints in allowing tumors to circumvent the immune system have led to successful therapeutic strategies that have fundamentally changed oncology practice. Thus far, immunotherapies against onl
Autor:
Youngsu Kwon, Avantika S. Chitre, Denise E. de Almeida Nagata, Karl L. Banta, Stephanie Mittman, Keith R. Anderson, Rafael Cubas, Kristin Harden Bowles, Patrícia de Almeida, Eugene Y. Chiang, Xiangnan Du, Søren Warming, Jane L. Grogan, Brent S. McKenzie
Publikováno v:
European Journal of Immunology. 50:891-902
CD96 is a member of the poliovirus receptor (PVR, CD155)-nectin family that includes T cell Ig and ITIM domain (TIGIT) and CD226. While CD96, TIGIT, and CD226 have important roles in regulating NK cell activity, and TIGIT and CD226 have also been sho
Autor:
Karl L, Banta, Xiaozheng, Xu, Avantika S, Chitre, Amelia, Au-Yeung, Chikara, Takahashi, William E, O'Gorman, Thomas D, Wu, Stephanie, Mittman, Rafael, Cubas, Laetitia, Comps-Agrar, Amit, Fulzele, Eric J, Bennett, Jane L, Grogan, Enfu, Hui, Eugene Y, Chiang, Ira, Mellman
Publikováno v:
Immunity. 55(3)
Dual blockade of the PD-1 and TIGIT coinhibitory receptors on T cells shows promising early results in cancer patients. Here, we studied the mechanisms whereby PD-1 and/or TIGIT blockade modulate anti-tumor CD8
Autor:
Karl L. Banta, Xiaozheng Xu, Avantika S. Chitre, Amelia Au-Yeung, Chikara Takahashi, William E. O’Gorman, Thomas D. Wu, Stephanie Mittman, Rafael Cubas, Laetitia Comps-Agrar, Amit Fulzele, Eric J. Bennett, Jane L. Grogan, Enfu Hui, Eugene Y. Chiang, Ira Mellman
Publikováno v:
Immunity. 55:512-526.e9