Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Eugene V. Grishin"'
Autor:
Yaroslav A. Andreev, Sergey A. Kozlov, Yuliya V. Korolkova, Igor A. Dyachenko, Dmitrii A. Bondarenko, Denis I. Skobtsov, Arkadii N. Murashev, Polina D. Kotova, Olga A. Rogachevskaja, Natalia V. Kabanova, Stanislav S. Kolesnikov, Eugene V. Grishin
Publikováno v:
Marine Drugs, Vol 11, Iss 12, Pp 5100-5115 (2013)
Transient receptor potential vanilloid 1 receptors (TRPV1) play a significant physiological role. The study of novel TRPV1 agonists and antagonists is essential. Here, we report on the characterization of polypeptide antagonists of TRPV1 based on in
Externí odkaz:
https://doaj.org/article/5aaa2041c8f74b2c940ee7ba1423b599
Autor:
Maxim V Nikolaev, Natalia A Dorofeeva, Margarita S Komarova, Yuliya V Korolkova, Yaroslav A Andreev, Irina V Mosharova, Eugene V Grishin, Denis B Tikhonov, Sergey A Kozlov
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177077 (2017)
TRPV1 (vanilloid) receptors are activated by different types of stimuli including capsaicin, acidification and heat. Various ligands demonstrate stimulus-dependent action on TRPV1. In the present work we studied the action of polypeptides isolated fr
Externí odkaz:
https://doaj.org/article/6a9ceedf0bbc47fe8bd54ee8f2cbed5f
Autor:
Peter B. Oparin, Anton O. Chugunov, Alyona F. Lihonosova, Antonina A. Berkut, Steve Peigneur, Valentin M. Tabakmakher, Alexander A. Vassilevski, Ekaterina V. Novikova, Konstantin S. Mineev, Roman G. Efremov, Nikolay A. Krylov, Jan Tytgat, Eugene V. Grishin, Alexander S. Arseniev
Publikováno v:
J Biol Chem
Tk-hefu is an artificial peptide designed based on the α-hairpinin scaffold, which selectively blocks voltage-gated potassium channels K(v)1.3. Here we present its spatial structure resolved by NMR spectroscopy and analyze its interaction with chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876ba469ad7832347896c92267059b31
https://doi.org/10.1074/jbc.ra119.010494
https://doi.org/10.1074/jbc.ra119.010494
Autor:
Nikita A. Kuldyushev, Jan Tytgat, Steve Peigneur, Konstantin S. Mineev, Antonina A. Berkut, Alexander A. Vassilevski, Eugene V. Grishin, Alexander S. Arseniev
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 86:1117-1122
Sodium channel alpha-toxins from scorpion venom (α-NaTx) inhibit the inactivation of voltage-gated sodium channels. We used solution NMR to investigate the structure of BeM9 toxin from Mesobuthus eupeus scorpion, a prototype α-NaTx classified as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c4c0461f1f6e0376890be86c8b3a58
https://doi.org/10.1002/prot.25583
https://doi.org/10.1002/prot.25583
Autor:
Eugene V. Grishin, Daniil Osipov, Antonina A. Berkut, Alexander A. Vassilevski, Evgeniia Lagereva, Anfisa Popova, Alexander Andreev-Andrievskiy
Publikováno v:
Toxicon. 138:59-67
Bites of tiger spiders belonging to Poecilotheria genus cause moderate to severe pain and long-lasting local or generalized muscle cramps in humans. Bites occur in regions of the spiders' natural habitat, India and Sri Lanka, but the popularity of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6033b7c44a4749d6ad6c350a70a69540
https://doi.org/10.1016/j.toxicon.2017.08.013
https://doi.org/10.1016/j.toxicon.2017.08.013
Autor:
Eugene V. Grishin, Antonina A. Berkut, Alexander A. Vassilevski, Jan Tytgat, Steve Peigneur, Nikita A. Kuldyushev
Publikováno v:
FEBS Letters. 591:3414-3420
Scorpion α-toxins are polypeptides that inhibit voltage-gated sodium channel inactivation. They are divided into mammal, insect and α-like toxins based on their relative activity toward different phyla. Several factors are currently known to influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8feb5393574df7803fd8fccd94a0ec25
https://doi.org/10.1002/1873-3468.12839
https://doi.org/10.1002/1873-3468.12839
Autor:
Kirill D. Nadezhdin, Maria Y. Sachkova, Alexander A. Vassilevski, Eugene V. Grishin, Peter B. Oparin, Alexander S. Arseniev, Daria D. Romanovskaia, Sergey I. Kovalchuk
Publikováno v:
Protein Science. 26:611-616
We have recently demonstrated that a common phenomenon in evolution of spider venom composition is the emergence of so-called modular toxins consisting of two domains, each corresponding to a “usual” single-domain toxin. In this paper, we describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71bfd7d9c7a4b9996046de15cd01c67f
https://doi.org/10.1002/pro.3101
https://doi.org/10.1002/pro.3101
Autor:
Eugene V. Grishin, Peter B. Oparin, Antonina A. Berkut, Alexander S. Arseniev, Alexander A. Vassilevski, Kirill D. Nadezhdin
Publikováno v:
Biochemical Journal. 473:3113-3126
Traditionally, arachnid venoms are known to contain two particularly important groups of peptide toxins. One is disulfide-rich neurotoxins with a predominance of β-structure that specifically target protein receptors in neurons or muscle cells. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234ef52248f0c09b0f9bff8fd9d11f71
https://doi.org/10.1042/bcj20160573
https://doi.org/10.1042/bcj20160573
Autor:
Alexey S. Vasilchenko, Anastasia V. Vasilchenko, Eugene A. Rogozhin, Eugene V. Grishin, Sergei K. Zavriev, A. N. Smirnov
Publikováno v:
International Journal of Peptide Research and Therapeutics. 23:171-180
Black seed (Nigella sativa) is known as a good source of various biologically active compounds which possess antimicrobial properties. One of our objectives was to elaborate methods of obtaining and extracting peptides from plants. In the current stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd4a783ae9ccd26f8101592bef8b053c
https://doi.org/10.1007/s10989-016-9549-1
https://doi.org/10.1007/s10989-016-9549-1
Autor:
Sergey K. Zavriev, Mikhail Yuryev, Alexey S. Vasilchenko, Alexey V. Feofanov, Dmitry Y. Ryazantsev, Eugene V. Grishin, Eugene A. Rogozhin
Publikováno v:
Scanning. 38:591-598
An interaction of recombinant hairpin-like cationic peptide EcAMP1 with conidia of plant pathogenic fungus Fusarium solani at the cellular level was studied by a combination of microscopic methods. EcAMP1 is from barnyard grass (Echinochloa crusgalli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8d3cc878dfc785ddd28b403361d0c9
https://doi.org/10.1002/sca.21305
https://doi.org/10.1002/sca.21305