Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Eugene Roets"'
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 105:205-211
The synthesis and characterization of a number of macrolides, structurally related with erythromycin, is described. These derivatives have been previously investigated for their ability to induce contractions and to displace bound motilin in rabbit d
Autor:
Yvan Vander Heyden, P. Baten, Eugene Roets, Béla Noszál, Jacques O. De Beer, Jos Hoogmartens, Tímea Iványi, Pieter Dehouck, Desire Massart, D. Visky, Zsuzsanna Kovács
Publikováno v:
Journal of Chromatography A. 1012:11-29
The European Pharmacopoeia (Ph. Eur.) and other official compendia give only a general description of the stationary phase in the description of a liquid chromatographic method. Therefore the selection of a column giving suitable selectivity presents
Publikováno v:
Chromatographia. 58:313-316
An improved LC method is described for the separation of doxycycline and its impurities. The separation of 2-acetyl-2-decarboxamidodoxycycline from the main peak doxycycline is much better than that obtained with official pharmacopoeia methods. The m
Autor:
Eugene Roets, Jos Hoogmartens, Erwin Adams, E. Haghedooren, Pieter Dehouck, K Deckers, E Van Looy, Y. Vander Heyden
Publikováno v:
Vrije Universiteit Brussel
Gels containing a combination of erythromycin and benzoylperoxide are frequently used in the treatment of acne vulgaris. A method was developed to determine the content of both erythromycin and benzoylperoxide in these gels. Erythromycin was extracte
Autor:
Chunlan Li, Jos Hoogmartens, Cindy Govaerts, Erwin Adams, J A Orwa, Ann Van Schepdael, Eugene Roets
Publikováno v:
Rapid Communications in Mass Spectrometry. 17:1366-1379
A selective reversed-phase liquid chromatography/mass spectrometry (LC/MSn) method is described for the characterization of related compounds in commercial bacitracin samples. Mass spectral data for these polypeptide antibiotics were acquired on a LC
Publikováno v:
Journal of Separation Science. 26:489-495
A simple, robust, sensitive, and selective liquid chromatography method suitable for the determination of the semi-synthetic antibiotic, josamycin propionate, and related substances is described. This method utilizes XTerra RP18 5 μm (25 cm×4.6 mm
Publikováno v:
Journal of Chromatography A. 996:115-131
The current method prescribed in official monographs for the purity control of vancomycin is inappropriate in that several components are not separated from each other and other components are coeluted with the main component vancomycin B. The method
Publikováno v:
Chromatographia. 57:671-675
A comparison of two LC methods for the separation of erythromycin is described. The first method was previously developed in this laboratory and uses an Xterra RP18 column. Acetonitrile-0.2 M K2HPO4 pH 7.0—water (35∶5∶60) is used as a mobile ph
Publikováno v:
ELECTROPHORESIS. 24:1119-1125
An electrophoretically mediated microanalysis (EMMA) approach, used to perform on-line chemistry between two small molecules, has been characterized and optimized. The plug-plug type EMMA method involved electrophoretic mixing and subsequent reaction
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 30:1331-1337
A reversed-phase liquid chromatography (LC) method has been developed, optimised and validated for the separation and quantitation of capsaicin (CP) and dihydrocapsaicin (DHCP) in a topical cream formulation. Sample preparation involves liquid-liquid