Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Eugene R. Zabarovsky"'
Autor:
Maria Li Lung, Eric J. Stanbridge, Johnny Cheuk On Tang, Sai Wah Tsao, Eugene R. Zabarovsky, Gopesh Srivastava, Simon Law, Yue Cheng, Josephine Mun Yee Ko, Fung Mei Kwong, Kwok Wah Chan, Suneel S. Apte, Arthur Kwok Leung Cheung, Hong Lok Lung, Paulisally Hau Yi Lo
ADAMTS metalloprotease family member ADAMTS9 maps to 3p14.2 and shows significant associations with the aerodigestive tract cancers esophageal squamous cell carcinoma (ESCC) and nasopharyngeal carcinoma (NPC). However, the functional impact of ADAMTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c7fd7d14881a3daa4a380e305d61b7
https://doi.org/10.1158/0008-5472.c.6500628.v1
https://doi.org/10.1158/0008-5472.c.6500628.v1
Autor:
Maria Li Lung, Eric J. Stanbridge, Johnny Cheuk On Tang, Sai Wah Tsao, Eugene R. Zabarovsky, Gopesh Srivastava, Simon Law, Yue Cheng, Josephine Mun Yee Ko, Fung Mei Kwong, Kwok Wah Chan, Suneel S. Apte, Arthur Kwok Leung Cheung, Hong Lok Lung, Paulisally Hau Yi Lo
Supplementary Table 1 from Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86e4216e2bb828373cd55a1172ee0ff
https://doi.org/10.1158/0008-5472.22383666.v1
https://doi.org/10.1158/0008-5472.22383666.v1
Autor:
Aleksandr G Kondratov, Sergiy M Kvasha, Liubov A Stoliar, Alina M Romanenko, Yury M Zgonnyk, Vasily V Gordiyuk, Elena V Kashuba, Alla V Rynditch, Eugene R Zabarovsky, Vladimir I Kashuba
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47012 (2012)
WNT7A (wingless-type MMTV integration site family, member 7A) is a known tumor suppressor gene of non-small cell lung carcinomas (NSCLC) and is frequently inactivated due to CpG-island hypermethylation in human cancers. The members of WNT family are
Externí odkaz:
https://doaj.org/article/9e9894dab0734e00b3543eb7b80ae3e7
Autor:
Vera N Senchenko, George S Krasnov, Alexey A Dmitriev, Anna V Kudryavtseva, Ekaterina A Anedchenko, Eleonora A Braga, Irina V Pronina, Tatiana T Kondratieva, Sergey V Ivanov, Eugene R Zabarovsky, Michael I Lerman
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e15612 (2011)
CHL1 gene (also known as CALL) on 3p26.3 encodes a one-pass trans-membrane cell adhesion molecule (CAM). Previously CAMs of this type, including L1, were shown to be involved in cancer growth and metastasis.We used Clontech Cancer Profiling Arrays (1
Externí odkaz:
https://doaj.org/article/f4aa5bf366ac4b26b848459e1e00abf8
Autor:
Vladimir I Kashuba, Tatiana V Pavlova, Elvira V Grigorieva, Alexey Kutsenko, Surya Pavan Yenamandra, Jingfeng Li, Fuli Wang, Alexei I Protopopov, Veronika I Zabarovska, Vera Senchenko, Klas Haraldson, Tatiana Eshchenko, Julia Kobliakova, Olga Vorontsova, Igor Kuzmin, Eleonora Braga, Vladimir M Blinov, Lev L Kisselev, Yi-Xin Zeng, Ingemar Ernberg, Michael I Lerman, George Klein, Eugene R Zabarovsky
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5231 (2009)
BACKGROUND:Many different genetic alterations are observed in cancer cells. Individual cancer genes display point mutations such as base changes, insertions and deletions that initiate and promote cancer growth and spread. Somatic hypermutation is a
Externí odkaz:
https://doaj.org/article/6ded5c2809ec482d9488ed168810d39c
Autor:
Fuli Wang, Elvira V Grigorieva, Jingfeng Li, Vera N Senchenko, Tatiana V Pavlova, Ekaterina A Anedchenko, Anna V Kudryavtseva, Alexander Tsimanis, Debora Angeloni, Michael I Lerman, Vladimir I Kashuba, George Klein, Eugene R Zabarovsky
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3031 (2008)
We identified two 3p21.3 regions (LUCA and AP20) as most frequently affected in lung, breast and other carcinomas and reported their fine physical and gene maps. It is becoming increasingly clear that each of these two regions contains several TSGs.
Externí odkaz:
https://doaj.org/article/9a40705768f24255878be751b7dee944
Autor:
Tatiana V. Pavlova, Malin Almgren, Imran Nawaz, Ziming Du, Eugene R. Zabarovsky, Ingemar Ernberg, Vladimir I. Kashuba, Ilya Ignatyev, Khalid Moumad, Li-Fu Hu
Publikováno v:
Oncotarget
Epigenetic silencing of tumor suppressor genes (TSGs) by promoter methylation can be an early event in the multi-step process of carcinogenesis. Human chromosome 3 contains clusters of TSGs involved in many cancer types including nasopharyngeal carci
Autor:
Vladimir I. Kashuba, Alexey A. Dmitriev, Fyodor L. Kisseljov, Evgeny B. Tsitrin, N. P. Kisseljova, Eugene R. Zabarovsky, George S. Krasnov, Michael I. Lerman, Grigory V. Panasenko, Tatyana A. Ivanova, Anna V. Kudryavtseva, V. N. Senchenko
Publikováno v:
Epigenetics. 8:409-420
Genetic and epigenetic alterations in cervical carcinomas were investigated using NotI-microarrays containing 180 cloned sequences flanking all NotI-sites associated with genes on chromosome 3. In total, 48 paired normal/tumor DNA samples, specifical
Autor:
Eugene R. Zabarovsky, Tatiana Y. Prudnikova, Vladimir I. Kashuba, Ingemar Ernberg, Luydmila A. Mostovich, Elvira V. Grigorieva
Publikováno v:
Epigenetics
microRNAs (miRNAs) are key posttranscriptional regulators of gene expression. In the present study, regulation of tumor-suppressor gene D-glucuronyl C5-epimerase (GLCE) by miRNA-218 was investigated. Significant downregulation of miRNA-218 expression
Autor:
Vladimir I. Kashuba, George Klein, Tatiana V. Pavlova, Ingemar Ernberg, Ilya Ignatjev, Vitalij I Loginov, Surya Pavan Yenamandra, Ekaterina A. Anedchenko, Eugene R. Zabarovsky, Tatiana T. Kondratieva, Klas Haraldson, Tatiana P. Kazubskaya, Anna V. Kudryavtseva, Alexey A. Dmitriev, George S. Krasnov, I. V. Pronina, Michael I. Lerman, V. N. Senchenko, Eleonora A. Braga
Publikováno v:
Epigenetics. 7:502-513
This study aimed to clarify genetic and epigenetic alterations that occur during lung carcinogenesis and to design perspective sets of newly identified biomarkers. The original method includes chromosome 3 specific NotI-microarrays containing 180 Not