Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eugene R. Mesco"'
Autor:
Eugene R. Mesco, Paola S. Timiras
Publikováno v:
Mechanisms of Ageing and Development. 61:1-9
The microtubule-associated protein tau, and the cytoplasmic protein ubiquitin, are constituents of pathological neurofibrillary tangles found in Alzheimer's disease. In order to see if there is any physiological relationship between these proteins in
Publikováno v:
Molecular and Chemical Neuropathology. 14:199-212
The presence of the trivalent metallic cations, aluminum and boron, in the culture medium of differentiated human LAN-5 neuroblastoma cells results in increased amounts of specific isomers of microtubule-associated tau proteins. The cells were differ
Publikováno v:
Brain Research. 545:355-357
Corpora striata of old rats (24-25 months) contain only about half as much mRNA for D2 dopamine receptors as those of young (6 months) counterparts. This reduction can be observed by in situ hybridization of brain slices as well as with Northern and
Publikováno v:
Brain research. Molecular brain research. 17(1-2)
Decreases in striatal dopamine receptors during aging are related to deficits in motor functions, and are highly correlated with the D2 receptor subtype. Some receptor loss is attributed to cell death, while the remainder is thought to be related to