Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eugene R. Baizman"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:2251-2254
The moenomycin trisaccharide degradation product and synthetic disaccharide analogues based on the disaccharide core were bactericidal to Gram-positive bacteria, inhibited lipid II polymerization, and inhibited cell wall synthesis in Entercoccus faec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373e9d6be2230072bf2693f5cb5ba5ab
https://doi.org/10.1016/s0960-894x(00)00443-1
https://doi.org/10.1016/s0960-894x(00)00443-1
Autor:
Sunita Midha, Clifford B. Longley, Kiho Han, Helena R. Axelrod, Arthur A. Branstrom, Eugene R. Baizman
Publikováno v:
Analytical Biochemistry. 280:315-319
Bacterial peptidoglycan synthesis is a well-characterized system for targeting new antimicrobial drugs. Formation of the peptidoglycan precursors Lipid I and Lipid II is catalyzed by the gene products of mraY and murG, which are involved in the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5ab22bdfde0ce7fd12bc2b055a85c5
https://doi.org/10.1006/abio.2000.4530
https://doi.org/10.1006/abio.2000.4530
Publikováno v:
FEMS Microbiology Letters. 183:209-214
Novel glycopeptide analogs are known that have activity on vancomycin resistant enterococci despite the fact that the primary site for drug interaction, D-ala-D-ala, is replaced with D-ala-D-lactate. The mechanism of action of these compounds may inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe7f26971f4f4fd0dbfccf6c98fdaa0
https://doi.org/10.1111/j.1574-6968.2000.tb08959.x
https://doi.org/10.1111/j.1574-6968.2000.tb08959.x
Autor:
Rui Liang, Chunguang Wang, Kiho Han, Nicole T. Hatzenbuhler, Buwen Huang, Muthoni G. Kamau, Helena R. Axelrod, Jan A. Anderson, Ramesh Kakarla, Neil Bristol, Anna Chen, Domingos J. Silva, Arthur Branstrom, Robert D. Goldman, Richard G. Dulina, Huiming Wang, Feng Chi, David Gange, Clifford B. Longley, Michael J. Sofia, Nigel M. Allanson, Dashan Liu, Rakesh K. Jain, Eugene R. Baizman, Natan A. Kogan, Sunita Midha
Publikováno v:
Journal of Medicinal Chemistry. 42:3193-3198
The increase in bacterial resistance to conventional chemotherapy has resulted in a resurgent interest in the discovery and development of antibacterial agents.1-4 The search for novel antibiotics active against resistant phenotypes is increasingly f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae445443dbe326863e7cdf3e76e733bc
https://doi.org/10.1021/jm990212a
https://doi.org/10.1021/jm990212a
Autor:
Robert J. Gordan, Chakrapani Subramanyam, W. Mark Eickhoff, Marion L. Drozd, David T. Robinson, Edward D. Pagani, Judith A. Johnson, Dennis J. Hlasta, Catherine A. Franke, Ranjit Ch Desai, Paul J. Silver, Alan L. Maycock, John F. Newton, Edward W. Ferguson, Dunlap Richard Paul, Eugene R. Baizman
Publikováno v:
Drug Development Research. 34:306-316
The proteolytic activity of human neutrophil elastase (HNE) has been implicated in a number of pulmonary diseases. We report on the activity of an orally bioavailable, selective HNE inhibitor, WIN 63759 [6-methoxy-4-(1-methylethy)-3-oxo-1,2-benzisoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b219826e23c3c6d5355f8c72f702212f
https://doi.org/10.1002/ddr.430340308
https://doi.org/10.1002/ddr.430340308
Autor:
Philip E. Hansen, Thomas D. Gordon, Barry A. Morgan, Eugene R. Baizman, Jasbir Singh, Susan J. Ward
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:915-920
Appropriately substituted thiazoles, imidazoles and oxazoles have been designed to be useful mimetics of dipeptide moieties. These “peptide azoles” have been shown to be potent antagonists of substances P as measured by isolated tissue assays suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d726b4a43e5b4dbc0c0a4b26aa37bc28
https://doi.org/10.1016/s0960-894x(00)80692-7
https://doi.org/10.1016/s0960-894x(00)80692-7
Autor:
Evgenia N Olsufyeva, Andrey Y. Pavlov, Robert C. Goldman, M. I. Reznikova, Eugene R. Baizman, Gyula Batta, Ferenc Sztaricskai, Maria N. Preobrazhenskaya, Clifford B. Longley, Elena B. Isakova, Arthur A. Branstrom, Elena P. Mirchink, Svetlana S. Printsevskaya
Publikováno v:
Journal of medicinal chemistry. 45(6)
Des-(N-methyl-D-leucyl)eremomycin was obtained by Edman degradation of eremomycin. Derivatives with a hydrophobic substituent at the exterior of the molecule were then synthesized, and their antibacterial activities were compared with similar derivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf9ca7d53c1f4d6ae9e5afb86dddc17
https://pubmed.ncbi.nlm.nih.gov/11882003
https://pubmed.ncbi.nlm.nih.gov/11882003
Publikováno v:
Bioorganicmedicinal chemistry letters. 10(24)
Bacterial Lipid I analogues containing different anomeric groups at the muramic acid moiety were synthesized and screened in MurG enzyme assays run in the presence and absence of cell wall membranes. The results obtained in this study help elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8654e58933d27b53430dd03ff5d98f5d
https://pubmed.ncbi.nlm.nih.gov/11133098
https://pubmed.ncbi.nlm.nih.gov/11133098
Autor:
Kure, Abhijeet S.1 (AUTHOR), Konda, Shankaraiah G.2 (AUTHOR), Chobe, Santosh S.3 (AUTHOR), Mandawad, Gajanan G.4 (AUTHOR), Hote, Baliram S.4 (AUTHOR) balwanthote7@rediffmail.com
Publikováno v:
Polycyclic Aromatic Compounds. 2023, Vol. 43 Issue 10, p8861-8872. 12p.
Autor:
Susan J. Ward, Doriann Keifer, Eugene R. Baizman, Barry A. Morgan, Jasbir Singh, Harry Bentley
Publikováno v:
Peptides ISBN: 9789401095976
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cb4f33f35e210ada2938bf3bd34c39f
https://doi.org/10.1007/978-94-010-9595-2_152
https://doi.org/10.1007/978-94-010-9595-2_152
