Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Eugene Pekary, A."'
Autor:
Albert Eugene Pekary, Albert Sattin
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background The TRH/TRH-R1 receptor signaling pathway within the neurons of the dorsal vagal complex is an important mediator of the brain-gut axis. Mental health and protection from a variety of neuropathologies, such as autism, Attention De
Externí odkaz:
https://doaj.org/article/2e2d80c9cbdf4151a977cf7fc3af4c68
Autor:
Albert Eugene Pekary, Albert Sattin
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 5, Iss 5, Pp n/a-n/a (2022)
Abstract Introduction Resveratrol and related polyphenols have therapeutic effects ranging from treatment of depression, Alzheimer's and Parkinson's disease, obesity, diabetes, neurodegeneration and ageing. TRH and TRH‐like peptides, with the struc
Externí odkaz:
https://doaj.org/article/6b3d5cbaa0794356b33f2c1499968963
Autor:
Albert Eugene Pekary, Albert Sattin
Publikováno v:
Endocrine and Metabolic Science, Vol 7, Iss , Pp 100121- (2022)
Background: Obesity, type 2 diabetes, and major depression are common comorbidities in aging populations. Metformin (MF) mimics effects of caloric restriction (CR) which increases health and life spans. CR suppresses central TRH activity resulting in
Externí odkaz:
https://doaj.org/article/47d8ffc1e7bf4afb8312f87a8edaaaca
Autor:
Albert Eugene Pekary, Albert Sattin
Publikováno v:
BMC neuroscience. 23(1)
Background The TRH/TRH-R1 receptor signaling pathway within the neurons of the dorsal vagal complex is an important mediator of the brain-gut axis. Mental health and protection from a variety of neuropathologies, such as autism, Attention Deficit Hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd97611c0f1767cff2e53d4897931d4
https://pubmed.ncbi.nlm.nih.gov/35189807
https://pubmed.ncbi.nlm.nih.gov/35189807
Publikováno v:
In Neurochemistry International 2002 41(6):415-428
Publikováno v:
Peptides. 69:66-76
Major depression is the largest single healthcare burden with treatments of slow onset and often limited efficacy. Ketamine, a NMDA antagonist used extensively as a pediatric and veterinary anesthetic, has recently been shown to be a rapid acting ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce13eb645f98d56fadbbe270810195bf
https://doi.org/10.1016/j.peptides.2015.04.003
https://doi.org/10.1016/j.peptides.2015.04.003
Autor:
Albert Eugene Pekary, Albert Sattin
Publikováno v:
Peptides. 52:1-10
Women are at greater risk for major depression, PTSD, and other anxiety disorders. ERβ-selective agonists for the treatment of these disorders are the focus of pharmacologic development and clinical testing. Estradiol and its metabolites contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19deedaaed96b8646b3077000729e641
https://doi.org/10.1016/j.peptides.2013.11.018
https://doi.org/10.1016/j.peptides.2013.11.018
Autor:
Albert Sattin, A. Eugene Pekary
Publikováno v:
Peptides. 36:157-167
Ghrelin is not only a modulator of feeding and energy expenditure but also regulates reproductive functions, CNS development and mood. Obesity and major depression are growing public health concerns which may derive, in part, from dysregulation of gh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3b7488cd5251254adb982766cf6bbc
https://doi.org/10.1016/j.peptides.2012.04.021
https://doi.org/10.1016/j.peptides.2012.04.021
Rapid modulation of TRH and TRH-like peptide release in rat brain and peripheral tissues by prazosin
Publikováno v:
Peptides. 32:1666-1676
Hyperresponsiveness to norepinephrine contributes to post-traumatic stress disorder (PTSD). Prazosin, a brain-active blocker of α1-adrenoceptors, originally used for the treatment of hypertension, has been reported to alleviate trauma nightmares, sl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e47c2b72feb755e1187c0d94285e80
https://doi.org/10.1016/j.peptides.2011.06.012
https://doi.org/10.1016/j.peptides.2011.06.012
Publikováno v:
Brain Research. 1345:9-18
Leptin is not only a feedback modulator of feeding and energy expenditure but also regulates reproductive functions, CNS development and mood. Obesity and major depression are growing public health concerns which may derive, in part, from disregulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2914c69a564b4964062f485b87cd804f
https://doi.org/10.1016/j.brainres.2010.05.039
https://doi.org/10.1016/j.brainres.2010.05.039