Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Eugene P. van Someren"'
1
Systems biology of personalized nutrition
Autor: André Boorsma, Eugene P. van Someren, Joshua C. Anthony, Iris M de Hoogh, Tim J. van den Broek, Marjan van Erk, Ben van Ommen, Wilrike Pasman, Tanja Rouhani-Rankouhi, Koen Hogenelst, Suzan Wopereis
Publikováno v: Nutrition Reviews, 8, 75, 579-599
Personalized nutrition is fast becoming a reality due to a number of technological, scientific, and societal developments that complement and extend current public health nutrition recommendations. Personalized nutrition tailors dietary recommendatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e3bf0bd0b1770e1a77e1c6d0ca0512
https://doi.org/10.1093/nutrit/nux029
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2
The DIAMONDS Platform
Autor: Harrie Buist, E. Dinant Kroese, Eugene P. van Someren, Danyel Jennen, Rob Stierum, Jack W. T. E. Vogels
Publikováno v: Handbook of Biomarkers and Precision Medicine ISBN: 9780429202872
This chapter describes the development of such a generic data management and data integration platform: Data-warehouse Infrastructure for Algorithms, Models and Ontologies toward Novel Design and Safety (DIAMONDS). The DIAMONDS platform consists of a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20e3945e1fb0c077a3d96bd0e4eb69ad
https://doi.org/10.1201/9780429202872-7
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3
Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks
Autor: Tessa E. Pronk, Jeroen L. A. Pennings, Eugene P. van Someren, Rob H. Stierum, Janine Ezendam
Publikováno v: Journal of Applied Toxicology. 33:1407-1415
The use of genes for distinguishing classes of toxicity has become well established. In this paper we combine the reconstruction of a gene dysregulation network (GDN) with a classifier to assign unseen compounds to their appropriate class. Gene pairs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00c3c647902ec71c24e4f759400de4e5
https://doi.org/10.1002/jat.2800
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4
'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans
Autor: Ad A. C. M. Peijnenburg, Arjen Lommen, Joost H.M. van Delft, Eugene P. van Someren, Marlon J. Jetten, Theo M. de Kok, Rob H. Stierum, Stan Gaj, Danyel Jennen, Sandra M.H. Claessen, Jos C. S. Kleinjans, Ainhoa Ruiz-Aracama
Publikováno v: Toxicology and Applied Pharmacology, 3, 259, 320-328
Toxicology and Applied Pharmacology, 259(3), 320-328. Elsevier Science
Toxicology and Applied Pharmacology, 259(3), 320-328
Toxicology and Applied Pharmacology 259 (2012) 3
Acetaminophen is the primary cause of acute liver toxicity in Europe/USA, which led the FDA to reconsider recommendations concerning safe acetaminophen dosage/use. Unfortunately, the current tests for liver toxicity are no ideal predictive markers fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a163eb831ad37a6dd72502a4d52a00a
https://doi.org/10.1016/j.taap.2012.01.009
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7
Effect of Chordin-Like 1 on MC3T3-E1 and Human Mesenchymal Stem Cells
Autor: Clemens van Blitterswijk, Ilse Steeghs, Anouk Mentink, Koen J. Dechering, Eugene P. van Someren, Hugo Fernandes, Marion Apotheker, Jan de Boer
Publikováno v: Cells tissues organs, 191, 443-452. Karger
Cells Tissues Organs, 191, 6, pp. 443-452
Cells Tissues Organs, 191, 443-452
Since the discovery that bone morphogenetic proteins (BMPs) are able to induce ectopic bone formation, considerable effort has been devoted to apply it for bone regeneration. BMP activity needs to be temporally and spatially controlled and the organi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366ca7a4574fa0fb951c0c1c27ceb0f5
https://doi.org/10.1159/000281825
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8
The Role of Collagen Crosslinking in Differentiation of Human Mesenchymal Stem Cells and MC3T3-E1 Cells
Autor: Hugo Fernandes, Marion Apotheker, Jan de Boer, Clemens van Blitterswijk, Ilse Steeghs, Anouk Leusink, Karolina Janeczek, Koen J. Dechering, Ruud A. Bank, Eugene P. van Someren
Publikováno v: Tissue Engineering Part A, 15, 12, pp. 3857-3867
Tissue Engineering Part A, 15, 3857-3867
Tissue Engineering. Part A, 15(12), 3857-3867. MARY ANN LIEBERT, INC
Tissue engineering. Part A, 15(12), 3857-3567. Mary Ann Liebert Inc.
Collagen is the main protein component of the extracellular matrix of bone, and it has structural and instructive properties. Collagen undergoes many post-translational modifications, including extensive crosslinking. Although defective crosslinking
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6c792b0b55760fcffa6afd797c1447
https://research.rug.nl/en/publications/7f6628e4-5505-41db-ba72-476b8f8f211e
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9
Integration of Known Transcription Factor Binding Site Information and Gene Expression Data to Advance from Co-Expression to Co-Regulation
Autor: Theo A. Knijnenburg, Marcel J. T. Reinders, Eugene P. van Someren, Maarten Clements
Publikováno v: Genomics, Proteomics & Bioinformatics
The common approach to find co-regulated genes is to cluster genes based on gene expression. However, due to the limited information present in any dataset, genes in the same cluster might be co-expressed but not necessarily co-regulated. In this pap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4ddf20f32aacf89ee25834e58a2153
https://doi.org/10.1016/s1672-0229(07)60019-9
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