Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Eugene P Kennedy"'
Autor:
Ramses Sadek, Mohammed Milhem, Olivier Rixe, David Munn, Christopher M Smith, Yousef Zakharia, Joseph Drabick, Kenneth F Grossmann, Robert R McWilliams, Montaser F Shaheen, Ravindra Kolhe, Rafal Pacholczyk, Lucinda L Tennant, Eugene P Kennedy, Charles J Link Jr, Nicholas N Vahanian, Jiayi Yu, Steven S Shen, Erik L Brincks, Gabriela R Rossi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background The indoleamine 2,3-dioxygenase (IDO) pathway is a key counter-regulatory mechanism that, in cancer, is exploited by tumors to evade antitumor immunity. Indoximod is a small-molecule IDO pathway inhibitor that reverses the immunosuppressiv
Externí odkaz:
https://doaj.org/article/3e3e02066379461ebd661d3bcc62f60a
Autor:
Kranti A. Mapuskar, Casey F. Pulliam, Ann Tomanek-Chalkley, Prerna Rastogi, Hsiang Wen, Sanjana Dayal, Benjamin R. Griffin, Diana Zepeda-Orozco, Amy L. Sindler, Carryn M. Anderson, Robert Beardsley, Eugene P. Kennedy, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103022- (2024)
Purpose: Cisplatin contributes to acute kidney injury (AKI) and chronic kidney disease (CKD) that occurs with greater frequency and severity in older patients. Age-associated cisplatin sensitivity in human fibroblasts involves increased mitochondrial
Externí odkaz:
https://doaj.org/article/700536df35bc4b5690c5fab7c5eab07c
Autor:
Jean-Paul Mosnier, Eugene T. Kennedy, Jean-Marc Bizau, Denis Cubaynes, Ségolène Guilbaud, Christophe Blancard, M. Fatih Hasoğlu, Thomas W. Gorczyca
Publikováno v:
Atoms, Vol 11, Iss 4, p 66 (2023)
This study reports on the absolute photoionization cross sections for the magnesium-like Cl5+ ion over the 190–370 eV photon energy range, corresponding to the L-shell (2s and 2p subshells) excitation regime. The experiments were performed using th
Externí odkaz:
https://doaj.org/article/9dd00cd1ff7f4560a0b0a56312751bf7
Autor:
Jonathan R. Brody, Myriam Gorospe, Charles J. Yeo, Judith C. Keen, Abhijit Dasgupta, Eugene P. Kennedy, Joseph A. Cozzitorto, Yuki Kuwano, Agnieszka K. Witkiewicz, Christina L. Costantino
Supplementary Figure 1 from The Role of HuR in Gemcitabine Efficacy in Pancreatic Cancer: HuR Up-regulates the Expression of the Gemcitabine Metabolizing Enzyme Deoxycytidine Kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a131a737d00b5572cce7ba8faa02c2a
https://doi.org/10.1158/0008-5472.22377980.v1
https://doi.org/10.1158/0008-5472.22377980.v1
Autor:
Stéphane Carniato, Jean-Marc Bizau, Denis Cubaynes, Eugene T. Kennedy, Ségolène Guilbaud, Emma Sokell, Brendan McLaughlin, Jean-Paul Mosnier
Publikováno v:
Atoms, Vol 8, Iss 4, p 67 (2020)
This article presents N2+ fragment yields following nitrogen K-shell photo-absorption in the NH+ molecular ion measured at the SOLEIL synchrotron radiation facility in the photon energy region 390–450 eV. The combination of the high sensitivity of
Externí odkaz:
https://doaj.org/article/d767efbe9d1c4305ac5fc16fa1fafb41
Autor:
Hu Lu, Lazaros Varvarezos, Patrick Hayden, Eugene T Kennedy, Jean-Paul Mosnier, John T Costello
Publikováno v:
Atoms, Vol 8, Iss 3, p 55 (2020)
The photoabsorption spectrum of Bi+ was measured in the wavelength range between 37 and 60 nm, using the dual laser plasma technique in which one plasma is used as the source of vacuum ultraviolet continuum radiation and the other plasma is used as t
Externí odkaz:
https://doaj.org/article/5c014daa66f64a74b727c2364d44628c
Autor:
Theodore S. Johnson, Rafal Pacholczyk, Zuzana Berrong, Chenbin Huang, Eugene P. Kennedy, Eric Ring, Ramses F. Sadek, Sarthak Satpathy, Beena E. Thomas, Tobey J. MacDonald, Manoj Bhasin, David H. Munn
Publikováno v:
Cancer Research. 83:LB200-LB200
Increasing evidence suggests that many of the effector CD8+ T cells reactivated (‘rejuvenated”) by immunotherapy come from outside the tumor, derived from a circulating pool of “stem-like” memory or “precursor-exhausted” (TPEX) cells. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73df14c45343473f96aaf505b7373135
https://doi.org/10.1158/1538-7445.am2023-lb200
https://doi.org/10.1158/1538-7445.am2023-lb200
Autor:
Hassan Hatoum, Charles J. Link, Nicholas N. Vahanian, Noelle K. LoConte, Lodovico Balducci, Gabriela R. Rossi, Raed Al-Rajabi, John Seng, Eugene P. Kennedy, Nicholas Nissen, Joshua Banks, Warren S. Brenner, Thomas J. George, Benjamin L. Musher, Emad Elquza, Harish Lavu, Charles J. Yeo, Benjamin E. Leiby, Andrew L. Coveler, Gina M. Vaccaro, D Brock Hewitt
Publikováno v:
Hepatobiliary Surg Nutr
Objectives To compare the efficacy and safety of algenpantucel-L (HAPa; IND# 12311) immunotherapy combined with standard of care (SOC) chemotherapy and chemoradiation to SOC chemotherapy and chemoradiation therapy alone in patients with borderline re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a242a9659f405faa3d0bf5072d91ac2
https://doi.org/10.1097/sla.0000000000004669
https://doi.org/10.1097/sla.0000000000004669
Autor:
Susan A. Melin, Petros Nikolinakos, Shou-Ching Tang, Krzysztof Lesniewski-Kmak, Ibrahim Nuhad, Paul B. Gilman, Veronica Mariotti, Patrick M. Dillon, Oana Cristina Danciu, Dhimant Patel, Eugene P. Kennedy, Alberto J. Montero, Malgorzata Suszko-Kazarnowicz, Hatem Soliman, Andrew Poklepovic, Roohi Ismail-Khan, Hyo S. Han, Boguslawa Karaszewska, Fabio Volterra, Daniel Bruetman, Timothy Panella
Publikováno v:
Cancer Research. 80:PD1-04
Background: IDO1 is a mediator of tumor immune suppression through alteration of tryptophan metabolism. Indoximod (1-methyl-tryptophan) is an IDO1 pathway inhibitor. There is preclinical evidence that indoximod acts synergistically with chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a2d6acf983b3c167bb771704f6c677f
https://doi.org/10.1158/1538-7445.sabcs19-pd1-04
https://doi.org/10.1158/1538-7445.sabcs19-pd1-04
Autor:
Montaser Shaheen, Jiayi Yu, Charles J. Link, Yousef Zakharia, Ramses F. Sadek, Robert R. McWilliams, Mohammed M. Milhem, Lucinda Tennant, Joseph J. Drabick, Olivier Rixe, Kenneth F. Grossmann, Gabriela R. Rossi, Nicholas N. Vahanian, Erik L. Brincks, Eugene P. Kennedy, Ravindra Kolhe, David H. Munn, Steven S. Shen, Christopher M Smith, Rafal Pacholczyk
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
BackgroundThe indoleamine 2,3-dioxygenase (IDO) pathway is a key counter-regulatory mechanism that, in cancer, is exploited by tumors to evade antitumor immunity. Indoximod is a small-molecule IDO pathway inhibitor that reverses the immunosuppressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc9351fdf41eb595ff4d0f8896211d3
https://pubmed.ncbi.nlm.nih.gov/34117113
https://pubmed.ncbi.nlm.nih.gov/34117113