Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eugene Muratov"'
Autor:
Renata Priscila Barros de Menezes, Jéssika de Oliveira Viana, Eugene Muratov, Luciana Scotti, Marcus Tullius Scotti
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 1, Pp 383-408 (2022)
Schistosomiasis is a chronic parasitic disease caused by trematodes of the genus Schistosoma; it is commonly caused by Schistosoma mansoni, which is transmitted by Bioamphalaria snails. Studies show that more than 200 million people are infected and
Externí odkaz:
https://doaj.org/article/1e697a89e1cb4e71ae7be602ab79e1de
Autor:
Arthur C. Silva, Joyce V.V.B. Borba, Vinicius M. Alves, Steven U.S. Hall, Nicholas Furnham, Nicole Kleinstreuer, Eugene Muratov, Alexander Tropsha, Carolina Horta Andrade
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 1, Iss , Pp 100028- (2021)
Eye irritation and corrosion are fundamental considerations in developing chemicals to be used in or near the eye, from cleaning products to ophthalmic solutions. Unfortunately, animal testing is currently the standard method to identify compounds th
Externí odkaz:
https://doaj.org/article/ad54c918e2eb4cd0838c8e3d6622e4ac
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/135ffeffdb3f4da0b8815b58144eccee
Autor:
Valeria V. Kleandrova, Luciana Scotti, Francisco Jaime Bezerra Mendonça Junior, Eugene Muratov, Marcus T. Scotti, Alejandro Speck-Planche
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Parasitic diseases remain as unresolved health issues worldwide. While for some parasites the treatments involve drug combinations with serious side effects, for others, chemical therapies are inefficient due to the emergence of drug resistance. This
Externí odkaz:
https://doaj.org/article/222816b043204389880ea1cc6c030629
Autor:
Melina Mottin, Joyce Villa Verde Bastos Borba, Cleber Camilo Melo-Filho, Bruno Junior Neves, Eugene Muratov, Pedro Henrique Monteiro Torres, Rodolpho Campos Braga, Alexander Perryman, Sean Ekins, Carolina Horta Andrade
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss spe (2018)
Few Zika virus (ZIKV) outbreaks had been reported since its first detection in 1947, until the recent epidemics occurred in South America (2014/2015) and expeditiously became a global public health emergency. This arbovirus reached 0.5-1.3 million ca
Externí odkaz:
https://doaj.org/article/3735805d6eab40919cf58a7d4fb4c0ee
Autor:
David H Drewry, Carrow I Wells, David M Andrews, Richard Angell, Hassan Al-Ali, Alison D Axtman, Stephen J Capuzzi, Jonathan M Elkins, Peter Ettmayer, Mathias Frederiksen, Opher Gileadi, Nathanael Gray, Alice Hooper, Stefan Knapp, Stefan Laufer, Ulrich Luecking, Michael Michaelides, Susanne Müller, Eugene Muratov, R Aldrin Denny, Kumar S Saikatendu, Daniel K Treiber, William J Zuercher, Timothy M Willson
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181585 (2017)
Protein kinases are highly tractable targets for drug discovery. However, the biological function and therapeutic potential of the majority of the 500+ human protein kinases remains unknown. We have developed physical and virtual collections of small
Externí odkaz:
https://doaj.org/article/ca1842e46c3c4d9282fcf8bc425a50a8
Autor:
Sean Ekins, Daniel Mietchen, Megan Coffee, Thomas P Stratton, Joel S Freundlich, Lucio Freitas-Junior, Eugene Muratov, Jair Siqueira-Neto, Antony J Williams, Carolina Andrade
Publikováno v:
F1000Research, Vol 5 (2016)
The Zika virus (ZIKV) outbreak in the Americas has caused global concern that we may be on the brink of a healthcare crisis. The lack of research on ZIKV in the over 60 years that we have known about it has left us with little in the way of starting
Externí odkaz:
https://doaj.org/article/a25d8021d75548d2a69e93f71fdc0e14
Autor:
Renata Priscila Barros de Menezes, Josean Fechine Tavares, Massuo Jorge Kato, Francisco Alex da Rocha Coelho, Holli-Joi Martin, Eugene Muratov, Airton Lucas Sousa dos Santos, Klinger Antonio da Franca Rodrigues, Luciana Scotti, Marcus Tullius Scotti
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Autor:
Guilherme Martins Silva, Vinicius Medeiros Alves, Suzane Quintana Gomes, Joshua Earl Hochuli, Eugene Muratov, Alexander Tropsha, Carlos Henrique Tomich Paula Silva
Glycogen Synthase Kinase-3 beta (GSK-3β) is a validated target-enzyme associated with Alzheimer’s Disease (AD). Usage of allosteric inhibitors of this enzyme represents a valid and promising therapeutic strategy due to their selective and subtle m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9895ca6dade4f62d5a5e89b074648ac4
https://doi.org/10.26434/chemrxiv-2023-q21sx
https://doi.org/10.26434/chemrxiv-2023-q21sx
Autor:
Marielle Rath, James Wellnitz, Holli-Joi Martin, Cleber Melo-Filho, Joshua Hochuli, Guilherme Martins da Silva, Jon-Michael Beasley, Travis Maxfield, Zoe Sessions, Konstantin Popov, Alexey Zakharov, Artem Cherkasov, Vinicius Alves, Eugene Muratov, Alexander Tropsha
Computational models that predict PK properties, such as those related to drug absorption, metabolism, distribution, and excretion, are critical to flagging drug candidates with poor PK profiles that emerge as hits in high-throughput screening campai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e30dfd74488af335c17be2422dc43c9f
https://doi.org/10.26434/chemrxiv-2023-rnc4l
https://doi.org/10.26434/chemrxiv-2023-rnc4l