Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Eugene Medlock"'
Autor:
David Chang, Jilin Sun, Marina Stolina, Shuqian Jing, Raffi Manoukian, Sheila Scully, Richard Yeh, Hung Q. Nguyen, Margaret L. DeRose, Gwyneth Van, Kristie Clarkin, Giorgio Senaldi, Dimitry M. Danilenko, Mee Rhan Kim, Eugene Medlock, Scott M. Silbiger, Yan Bin Yu, Gary Elliott
Publikováno v:
Blood. 100:2330-2340
We have identified and cloned a novel human cytokine with homology to cytokines of the interleukin-17 (IL-17) family, which we have termed human IL-17E (hIL-17E). With the identification of several IL-17 family members, it is critical to understand t
Autor:
Lisa D. Trebasky, Eugene Medlock, Adrienna Boynton, Nathan Bucay, Laarni Ulias, Scott M. Silbiger, Karen A. Augustine
Publikováno v:
The Anatomical Record. 258:221-234
Protein tyrosine phosphatases (PTPs) play important roles in modulating signals transduced by tyrosine kinases. Certain phosphatases have been implicated as having important roles in embryonic development as well as in adult physiology. Although both
Autor:
Dimitry M. Danilenko, Brian Varnum, Jerry M. Housman, Randall M. Rossi, Karen A. Augustine, Eugene Medlock, Gwenyth Van, Kevin Lee Stark
Publikováno v:
Journal of Cellular Physiology. 181:433-447
The axl tyrosine kinase receptor is aberrantly expressed on myeloid cells of many individuals afflicted with chronic myelogenous leukemia (CML) and other myeloid leukemias. Although previous studies demonstrated this kinase to have oncogenic potentia
Publikováno v:
Blood. 81:916-922
We studied the effect of recombinant human granulocyte colony- stimulating factor (rhG-CSF) administration to pregnant rats upon fetal and neonatal myelopoiesis. Pregnant rats were treated with rhG-CSF twice daily for 2, 4, and 6 days before parturit
Autor:
Keith Langley, Jerry M. Housman, Chrysa Mineo, Eugene Medlock, Krisztina M. Zsebo, Gary Elliott, Lisa D. Trebasky
Publikováno v:
Journal of Cellular Physiology. 153:498-506
Recent reports have shown that various marrow-derived cell populations respond vigorously to recombinant rat stem cell factor (rrSCF164), one form of the kitligand. In the present study, we isolated cell populations from rat bone marrow using the Thy
Autor:
Maren Geldmacher, Christoph Heberlein, Luke Li, Jutta Friel, Eugene Medlock, Carol Stocking, Katsuhiko Itoh, Naoki Nakayama, Wolfram Ostertag
Publikováno v:
Journal of cellular physiology. 206(2)
The hematopoietic stem cell line, Myl-D7, is maintained by a self-renewing stem cell population that spontaneously generates myeloid, lymphoid, and erythroid progeny. MS-5 stromal cells are necessary for the growth of Myl-D7 cells. One component of t
Autor:
Dimitry M. Danilenko, Melissa L. Graham, J M Cunningham, V Mar, John R. Shutter, R A Bosselman, J del Castillo, Kevin Lee Stark, Eugene Medlock, I L Ponting, Y Zuo, C P Perkins
Publikováno v:
Genesdevelopment. 11(7)
The mCAT-1 gene encodes a basic amino acid transporter that also acts as the receptor for murine ecotropic leukemia viruses. Targeted mutagenesis in embryonic stem cells has been used to introduce a germ-line null mutation into this gene. This mutati
Autor:
Eugene Medlock, R. Wayne Hendren, Jerry M. Housman, Dale L. Greiner, Randolph B. Deprince, Lisa D. Trebasky, Russell T. Migita, Gary Elliott
Publikováno v:
Developmental Immunology
Cytokine regulation of prethymic T-lymphoid progenitor-cell proliferation and/or differentiation has not been well-defined, although much is known of cytokine regulation of hemopoietic stem- and progenitor-cell development. Here we use a recently ide
Autor:
Irving Goldschneider, Kristin L. Komschlies, Dale L. Greiner, Christopher F. Mojcik, Eugene Medlock
Publikováno v:
Cellular Immunology. 114:336-346
The RT6 alloantigen is present on approximately 70% of peripheral T cells in the rat, but is absent from thymocytes and bone marrow lymphocytes. The results of further phenotypic analysis in the present study demonstrated that the RT6 alloantigen is
Publikováno v:
Cellular Immunology. 94:113-121
Neoplastic thymocytes from rat thymic lymphoma-leukemias induced by the rat-adapted Gross leukemia virus (RAGV) were analyzed for a variety of differentiation markers. The neoplasms from individual rats all expressed the antigenic phenotype MP + , W3