Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Eugene Malveaux"'
Autor:
Zhaobin Zhang, Jeffrey J. Olson, Mark M. Goodman, Vernon M. Camp, Lawrence E. Williams, Jonathan McConathy, Eugene Malveaux, Weiping Yu
Publikováno v:
Journal of Medicinal Chemistry. 53:876-886
The non-natural amino acids (R)- and (S)-2-amino-3-fluoro-2-methylpropanoic acid 5 and (R)- and (S)-3-fluoro-2-methyl-2-N-(methylamino)propanoic acid 8 were synthesized in shorter reaction sequences than in the original report starting from enantiome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa533d13af123001b1d888e4cd121e38
https://doi.org/10.1021/jm900556s
https://doi.org/10.1021/jm900556s
Autor:
Jonathan McConathy, Michael J. Owens, Eugene Malveaux, Charles B. Nemeroff, Mark M. Goodman, Clinton D. Kilts, John R. Votaw
Publikováno v:
Nuclear Medicine and Biology. 32:593-605
The development of radioligands suitable for studying the central nervous system (CNS) norepinephrine transporter (NET) in vivo will provide important new tools for examining the pathophysiology and pharmacotherapy of a variety of neuropsychiatric di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15e7e32d97657fb4227ec583c5d05c4
https://doi.org/10.1016/j.nucmedbio.2005.04.012
https://doi.org/10.1016/j.nucmedbio.2005.04.012
Autor:
Robin R. Goodman, John R. Votaw, Vernon M. Camp, Mark M. Goodman, Eugene Malveaux, Lawrence E. Williams, Jonathan McConathy, Nachwa Jarkas, Ronald J. Voll, Clinton D. Kilts
Publikováno v:
Nuclear Medicine and Biology. 32:75-86
[ 11 C] N , N -Dimethyl-2-(2′-amino-4′-ethylphenylthio)benzylamine ([ 11 C]EADAM) was synthesized in the development of a serotonin transporter (SERT) imaging ligand for positron emission tomography (PET). The methods of ligand synthesis, results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43f38814e2d3fd908674f70d2774630
https://doi.org/10.1016/j.nucmedbio.2004.07.001
https://doi.org/10.1016/j.nucmedbio.2004.07.001
Autor:
Jonathan McConathy, Nicholas E. Simpson, Eugene Malveaux, Vernon M. Camp, Laurent Martarello, Geoffrey Bowers, Mark M. Goodman, Jeffrey J. Olson, Chiab P. Simpson
Publikováno v:
Journal of Medicinal Chemistry. 45:2250-2259
syn- and anti-1-amino-3-[18F]fluoromethyl-cyclobutane-1-carboxylic acid (FMACBC, 16 and 17), analogues of anti-1-amino-3-[18F]fluorocyclobutyl-1-carboxylic acid (FACBC), were prepared to evaluate the contributions of C-3 substitution and configuratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a0b77908fd3d82c78348a6e99d56f4
https://doi.org/10.1021/jm010242p
https://doi.org/10.1021/jm010242p
Autor:
Bing Shi, Timothy D. Ely, Mark M. Goodman, John M. Hoffman, John R. Votaw, Michael J. Owens, Vernon M. Camp, Robert Keil, Eugene Malveaux, Dongxia Xing, Clinton D. Kilts, Philip D. Lambert, Laurent Martarello
Publikováno v:
Nuclear Medicine and Biology. 27:1-12
Fluorine-18 labeled 2beta-carbomethoxy-3beta-(4-chlorophenyl)-8-(2-fluoroethyl)nort ropane (FECNT) was synthesized in the development of a dopamine transporter (DAT) imaging ligand for positron emission tomography (PET). The methods of radiolabeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e9547379ce816d517c6dde515fb9ef
https://doi.org/10.1016/s0969-8051(99)00080-3
https://doi.org/10.1016/s0969-8051(99)00080-3
Autor:
Mel Camp, Laurent Martarello, Geoffrey Bowers, Jonathan McConathy, Eugene Malveaux, Mark M. Goodman, Jeffrey J. Olson
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S385-S387
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dafbf27094658f5ddfb4b8f20577c5f3
https://doi.org/10.1002/jlcr.25804401136
https://doi.org/10.1002/jlcr.25804401136
Autor:
Eugene Malveaux, Jeffrey J. Olson, Weiping Yu, Vernon M. Camp, Mark M. Goodman, Lawrence E. Williams
Publikováno v:
Bioorganicmedicinal chemistry. 17(5)
Amino acid syn -1-amino-3-fluoro-cyclobutyl-1-carboxylic acid ( syn- FACBC) 12 , the isomer of anti -FACBC, has been selectively synthesized and [ 18 F] radiofluorinated in 52% decay-corrected yield using no-carrier-added [ 18 F]fluoride. The key ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8d68cf827ce8921b3990b198bf2125
https://pubmed.ncbi.nlm.nih.gov/19216081
https://pubmed.ncbi.nlm.nih.gov/19216081
Autor:
Weiping Yu, Mark M. Goodman, Eugene Malveaux, Lawrence E. Williams, Vernon M. Camp, Jeffrey J. Olson
syn- and anti-1-amino-3-[2-iodoethenyl]-cyclobutane-1-carboxylic acid (syn-, anti-IVACBC 16, 17) and their analogue 1-amino-3-iodomethylene-cyclobutane-1-carboxylic acid (gem-IVACBC 18) were synthesized and radioiodoinated with [(123)I] in 34-43% del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf04c41ddfb60ceeddd793c87ffc506
https://europepmc.org/articles/PMC2362394/
https://europepmc.org/articles/PMC2362394/
Akademický článek
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Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 45(5)
99mTc-Mercaptoacetyltriglycine ((99m)Tc-MAG3) and (99m)Tc-L,L-ethylenedicysteine ((99m)Tc-LL-EC) are useful renal radiopharmaceuticals; however, both agents have renal clearances less than that of (131)I-orthoiodohippurate ((131)I-OIH), and (99m)Tc-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bf0d8faa81433ba990acd4544026bc9
https://pubmed.ncbi.nlm.nih.gov/15136640
https://pubmed.ncbi.nlm.nih.gov/15136640