Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain

Autor: Dmitrii Kulbatskii, Zakhar Shenkarev, Maxim Bychkov, Eugene Loktyushov, Mikhail Shulepko, Sergey Koshelev, Igor Povarov, Alexander Popov, Steve Peigneur, Anton Chugunov, Sergey Kozlov, Irina Sharonova, Roman Efremov, Vladimir Skrebitsky, Jan Tytgat, Mikhail Kirpichnikov, Ekaterina Lyukmanova

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Lypd6 is a GPI-tethered protein from the Ly-6/uPAR family expressed in the brain. Lypd6 enhances the Wnt/β-catenin signaling, although its action on nicotinic acetylcholine receptors (nAChRs) have been also proposed. To investigate a cholinergic act

Externí odkaz: https://doaj.org/article/a865cba71d844068a019acd3c7b696bb

Glycosylation of Receptor Binding Domain of SARS-CoV-2 S-Protein Influences on Binding to Immobilized DNA Aptamers

Autor: Fedor Grabovenko, Liudmila Nikiforova, Bogdan Yanenko, Andrey Ulitin, Eugene Loktyushov, Timofei Zatsepin, Elena Zavyalova, Maria Zvereva

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 557
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 557, p 557 (2022)

Nucleic acid aptamers specific to S-protein and its receptor binding domain (RBD) of SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus 2) virions are of high interest as potential inhibitors of viral infection and recognizing elements

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50d5c9dc02b9a0a44037bbb45fb89fc
https://doi.org/10.3390/ijms23010557