Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eugene L. Patkin"'
Autor:
Irina O. Suchkova, Kinda Ali Sharrouf, Liudmila K. Sasina, Natalia I. Dergacheva, Tatyana V. Baranova, Eugene L. Patkin
Publikováno v:
Medical academic journal. 22:77-96
BACKGROUND: Neuroblastoma is one of the most common extracranial solid tumors in childhood. At present, epigenetic disorders play a significant role in neoplasms development. Since epigenetic changes in the cell are quite dynamic and reversible, epig
Autor:
Liubov A. Postnikova, Ekaterina M. Noniashvili, Irina O. Suchkova, Tatyana V. Baranova, Eugene L. Patkin
Publikováno v:
Medical academic journal. 22:45-56
BACKGROUND: Bisphenol A is a chemical agent ubiquitous in plastic consumer products and a toxin capable of disrupting key epigenetic mechanisms in early embryogenesis. It becomes more and more clear that early development changes in epigenetic pathwa
Autor:
Liubov A. Postnikova, Eugene L. Patkin
Publikováno v:
Birth Defects Research. 114:1199-1209
The main objective of this review was to state a hypothetical mechanism of the antitoxic effect of lactoferrin (Lf) on embryos exposed to bisphenol A (BPA). On this basis, it is possible to suggest Lf as a potential protective health component before
Publikováno v:
International Journal of Molecular Sciences
Epilepsy is a neurological disease with different clinical forms and inter-individuals heterogeneity, which may be associated with genetic and/or epigenetic polymorphisms of tandem-repeated noncoding DNA. These polymorphisms may serve as predictive b
Autor:
Eugene L Patkin, Henry A Sofronov
Publikováno v:
Экологическая генетика, Vol 10, Iss 4, Pp 14-28 (2012)
The review critically examines the current state of population epigenetics. Possible mechanisms of intergenerational inheritance of epigenetic and epigenomic modifications as a condition of population epigenetics reality are examined. Special attenti
Autor:
Eugene L Patkin, John P. Quinn
Publikováno v:
Экологическая генетика, Vol 8, Iss 4, Pp 44-56 (2010)
Contemporary data concerned an input of epigenetical mechanisms into an etiology and susceptibility to complex human diseases are critically analyzed. The special attention is attended to a specific role of simple tandem DNA repeats, the crucial role
Publikováno v:
Experimental physiology. 93(5)
Mas is the receptor for angiotensin-(1-7) and is involved in cardiovascular and neuronal regulation, in which the heptapeptide also plays a major role. Mas-deficient mice have been generated by us, and their characterization has shown that Mas has im
Autor:
Eugene L, Patkin
Publikováno v:
International review of cytology. 216
This review examines main developments related to the interface between primary mammalian cell differentiation and various aspects of chromosomal structure changes, such as heterochromatin dynamics, DNA methylation, mitotic recombination, and inter-