Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Eugene Khandros"'
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101070- (2022)
Summary: Early erythroid progenitors are transit-amplifying cells with high proliferative capacity committed to undergoing red cell differentiation. CD71/CD24low progenitors are less mature and have greater proliferative capacity than CD71/CD24high.
Externí odkaz:
https://doaj.org/article/16c7792470e74697a28805fb7853c257
Autor:
Satheesh Chonat, Mary Risinger, Haripriya Sakthivel, Omar Niss, Jennifer A. Rothman, Loan Hsieh, Stella T. Chou, Janet L. Kwiatkowski, Eugene Khandros, Matthew F. Gorman, Donald T. Wells, Tamara Maghathe, Neha Dagaonkar, Katie G. Seu, Kejian Zhang, Wenying Zhang, Theodosia A. Kalfa
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/840996a63d2c4519a193f1ac68e710b4
Autor:
Satheesh Chonat, Mary Risinger, Haripriya Sakthivel, Omar Niss, Jennifer A. Rothman, Loan Hsieh, Stella T. Chou, Janet L. Kwiatkowski, Eugene Khandros, Matthew F. Gorman, Donald T. Wells, Tamara Maghathe, Neha Dagaonkar, Katie G. Seu, Kejian Zhang, Wenying Zhang, Theodosia A. Kalfa
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Hereditary spherocytosis (HS) is the most common red blood cell (RBC) membrane disorder causing hereditary hemolytic anemia. Patients with HS have defects in the genes coding for ankyrin (ANK1), band 3 (SLC4A1), protein 4.2 (EPB42), and α (SPTA1) or
Externí odkaz:
https://doaj.org/article/ad840012f1744b04820b5b66c13c0ebd
Autor:
Kunhua Qin, Peng Huang, Ruopeng Feng, Cheryl A. Keller, Scott A. Peslak, Eugene Khandros, Megan S. Saari, Xianjiang Lan, Thiyagaraj Mayuranathan, Phillip A. Doerfler, Osheiza Abdulmalik, Belinda Giardine, Stella T. Chou, Junwei Shi, Ross C. Hardison, Mitchell J. Weiss, Gerd A. Blobel
Publikováno v:
Nature Genetics. 54:874-884
Autor:
Kunhua Qin, Xianjiang Lan, Peng Huang, Megan S. Saari, Eugene Khandros, Cheryl A Keller, Belinda M. Giardine, Osheiza Abdulmalik, Junwei Shi, Ross C. Hardison, Gerd A. Blobel
Publikováno v:
Blood.
The fetal (HbF)-to-adult (HbA) hemoglobin switch is a paradigm for developmental gene expression control with relevance to sickle cell disease and b-thalassemia. Polycomb repressive complex (PRC) proteins regulate this switch, and an inhibitor of PRC
Autor:
Peng Huang, Scott A. Peslak, Ren Ren, Eugene Khandros, Kunhua Qin, Cheryl A. Keller, Belinda Giardine, Henry W. Bell, Xianjiang Lan, Malini Sharma, John R. Horton, Osheiza Abdulmalik, Stella T. Chou, Junwei Shi, Merlin Crossley, Ross C. Hardison, Xiaodong Cheng, Gerd A. Blobel
Publikováno v:
Nat Genet
The fetal-to-adult switch in hemoglobin production is a model of developmental gene control with relevance to the treatment of hemoglobinopathies. The expression of transcription factor BCL11A, which represses fetal β-type globin (HBG) genes in adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b27f4d476434f6a5f7d6ba96595d359
https://europepmc.org/articles/PMC9940634/
https://europepmc.org/articles/PMC9940634/
Autor:
Peng Huang, Eugene Khandros, Scott A. Peslak, Cheryl A. Keller, Belinda M. Giardine, Ross C. Hardison, Gerd A. Blobel
Publikováno v:
Blood. 140:1937-1938
Autor:
Kunhua Qin, Peng Huang, Xianjiang Lan, Megan S. Saari, Eugene Khandros, Osheiza Y. Abdulmalik, Cheryl A. Keller, Belinda M. Giardine, Ross C. Hardison, Junwei Shi, Gerd A. Blobel
Publikováno v:
Blood. 140:5382-5383
Autor:
Aoi Wakabayashi, Maryanne Kihiu, Malini Sharma, A. Josephine Thrasher, Megan S. Saari, Mathieu Quesnel-Vallières, Osheiza Abdulmalik, Scott A. Peslak, Eugene Khandros, Cheryl A. Keller, Belinda M. Giardine, Yoseph Barash, Ross C. Hardison, Junwei Shi, Gerd A. Blobel
Publikováno v:
Blood advances. 6(23)
The fetal-to-adult hemoglobin transition is clinically relevant because reactivation of fetal hemoglobin (HbF) significantly reduces morbidity and mortality associated with sickle cell disease (SCD) and β-thalassemia. Most studies on the development
Autor:
Marit W. Vermunt, Jing Luan, Zhe Zhang, A. Josephine Thrasher, Anran Huang, Megan S. Saari, Eugene Khandros, Robert A. Beagrie, Shiping Zhang, Pranay Vemulamada, Matilda Brilleman, Kiwon Lee, Jennifer A. Yano, Belinda M. Giardine, Cheryl A. Keller, Ross C. Hardison, Gerd A. Blobel
Publikováno v:
Molecular Cell. 83:715-730.e6