Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Eugene J.-M.A. Thonar"'
Publikováno v:
Spine. 36:372-377
Study Design In vivo randomized controlled study in the goat intervertebral disc (IVD) injury model.
Autor:
D. Greg Anderson, Dessislava Markova, Tong-Chuan He, Howard S. An, Wenyang Hu, Eugene J.-M.A. Thonar, Frank M. Phillips, Yejia Zhang, Hee Jeong Im
Publikováno v:
American Journal of Physical Medicine & Rehabilitation. 88:455-463
To confirm that primary intervertebral disc cells cultured in monolayer transduced with adenovirus maintained their phenotype, hence is an appropriate system to test gene therapy agents.Adult bovine nucleus pulposus and anulus fibrosus cells cultured
Autor:
Christopher B. Forsyth, Michael B. Ellman, Xin Li, Gun-Hee Kim, Francesca J. Davis, Prasuna Muddasani, Eugene J.-M.A. Thonar, Jayanthi Rangan, Hee Jeong Im
Publikováno v:
Journal of Cellular Physiology. 215:452-463
Pain-related neuropeptides released from synovial fibroblasts, such as substance P, have been implicated in joint destruction. Substance P-induced inflammatory processes are mediated via signaling through a G-protein-coupled receptor, that is, neurok
Publikováno v:
The Spine Journal. 7:694-700
One of the advantages of chemonucleolysis for the treatment of a herniated intervertebral disc is the potential for the disc to self-repair. It has been suggested that the enzymes used for chemonucleolysis differentially affect the potential of the d
Autor:
Kei Miyamoto, Howard S. An, Koichi Masuda, Gunnar Andersson, Eugene J.-M.A. Thonar, Yoshiyuki Imai
Publikováno v:
Spine. 32:1303-1309
Study Design. In vitro assessment of the effects of recombinant human osteogenic protein-1 (rhOP-1) on the proteoglycan metabolism of human intervertebral disc cells. Objectives. To determine whether rhOP-1 is effective in stimulating the cell prolif
Autor:
Anthony J. Aldave, Sylvia A. Rayner, Eugene J.-M.A. Thonar, Baris Sonmez, Vivek S. Yellore, Michael C. Chen
Publikováno v:
Ophthalmic Genetics. 28:169-174
To report an unusual phenotype of macular corneal dystrophy (MCDC1) associated with a novel CHST6 mutation transmitted via maternal isodisomy.Slit lamp examination of the patient and his parents was performed. DNA was collected from each individual f
Autor:
Eugene J.-M.A. Thonar, Susan Chubinskaya, Yejia Zhang, Tong-Chuan He, Howard S. An, Frank M. Phillips
Publikováno v:
Spine. 31:2173-2179
Study design An in vitro biologic study of the effects of adenovirus expressing bone morphogenetic proteins (BMPs) and adenovirus expressing Sox9 on extracellular matrix metabolism by bovine nucleus pulposus cells. Objective To compare the effects of
Autor:
Carol Muehleman, Eugene J.-M.A. Thonar, Yoichi Aota, Howard S. An, Yoshiyuki Imai, Koichi Masuda
Publikováno v:
Cell and Tissue Research. 326:787-793
Lipopolysaccharide (LPS) induces matrix degradation and markedly stimulates the production of several cytokines, i.e., interleukin-1beta, -6, and -10, by disc cells and chondrocytes. We performed a series of experiments to compare cellular responses
Publikováno v:
Osteoarthritis and Cartilage. 14:384-391
Summary Objective This study examined the effects of a growth factor, recombinant human osteogenic protein-1 (rhOP-1), on the formation of tissue-engineered cartilaginous tissue by adult bovine articular chondrocytes using the alginate-recovered-chon
Autor:
Rajeswari Pichika, Atsumasa Uchida, Koji Akeda, Mary Ellen Lenz, Howard S. An, Koichi Masuda, Eugene J.-M.A. Thonar, Mohamed Attawia
Publikováno v:
Spine. 31:959-966
Study design In vitro assessment of the effects of platelet-rich plasma on the extracellular matrix metabolism of porcine intervertebral disc cells. Objectives To determine whether platelet-rich plasma is effective in stimulating cell proliferation a