Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Eugene I. Hwang"'
Autor:
Kajal Chaudhry, Ashley Geiger, Ehsan Dowlati, Haili Lang, Danielle K. Sohai, Eugene I. Hwang, Christopher A. Lazarski, Eric Yvon, Matthias Holdhoff, Richard Jones, Barbara Savoldo, Conrad Russell Y. Cruz, Catherine M. Bollard
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 415-430 (2022)
Cord blood (CB)-derived natural killer (NK) cells that are genetically engineered to express a chimeric antigen receptor (CAR) are an attractive off-the-shelf therapy for the treatment of cancer, demonstrating a robust safety profile in vivo. For poo
Externí odkaz:
https://doaj.org/article/2478a16e444f4187b1167f6bf2ee7d0f
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 39, Iss , Pp 100895- (2023)
Pediatric intracranial ependymoma has seen a recent exponential expansion of biological findings, rapidly dividing the diagnosis into several subgroups, each with specific molecular and clinical characteristics. While such subdivision may complicate
Externí odkaz:
https://doaj.org/article/47fd6b923a984b0892d3df6321ff8cfa
Autor:
Stewart Goldman, Ashley Margol, Eugene I. Hwang, Kazuhiro Tanaka, Bogdana Suchorska, John R. Crawford, Santosh Kesari
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
There is an unmet need to develop effective and tolerable treatments for pediatric patients with malignant central nervous system tumors. This is especially essential for pediatric patients with aggressive brain tumors such as high-grade gliomas, whi
Externí odkaz:
https://doaj.org/article/3d886f68a788431b80bb25f20dc8a574
Autor:
Allison B. Powell, Sridevi Yadavilli, Devin Saunders, Stacey Van Pelt, Elizabeth Chorvinsky, Rachel A. Burga, Shuroug Albihani, Patrick J. Hanley, Zhenhua Xu, Yanxin Pei, Eric S. Yvon, Eugene I. Hwang, Catherine M. Bollard, Javad Nazarian, Conrad Russell Y. Cruz
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Medulloblastoma (MB), the most common pediatric brain cancer, presents with a poor prognosis in a subset of patients with high risk disease, or at recurrence, where current therapies are ineffective. Cord blood (CB) natural killer
Externí odkaz:
https://doaj.org/article/c9184b94467c470fae4a1a2e1c6345e2
Autor:
Hamid Nikbakht, Eshini Panditharatna, Leonie G. Mikael, Rui Li, Tenzin Gayden, Matthew Osmond, Cheng-Ying Ho, Madhuri Kambhampati, Eugene I. Hwang, Damien Faury, Alan Siu, Simon Papillon-Cavanagh, Denise Bechet, Keith L. Ligon, Benjamin Ellezam, Wendy J. Ingram, Caedyn Stinson, Andrew S. Moore, Katherine E. Warren, Jason Karamchandani, Roger J. Packer, Nada Jabado, Jacek Majewski, Javad Nazarian
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Diffuse Intrinsic Pontine Gliomas are diagnosed by sampling a small portion of the tumour. Here, using multiple samples from tumours, the authors analyse the spatial and temporal distribution of driver mutations revealing that H3K27M mutations arise
Externí odkaz:
https://doaj.org/article/ca732472c78c4cee9e8f045e01b29088
Publikováno v:
Translational Oncology, Vol 9, Iss 1, Pp 57-63 (2016)
Neuron glia antigen-2 ((NG2), also known as chondroitin sulphate proteoglycan 4, or melanoma-associated chondroitin sulfate proteoglycan) is a type-1 membrane protein expressed by many central nervous system (CNS) cells during development and differe
Externí odkaz:
https://doaj.org/article/76b3914658234cbfab7c40718bd2740b
Autor:
Erin E. Crotty, Ashley L. Wilson, Tom Davidson, Sophia Tahiri, Juliane Gust, Andrea M. Griesinger, Sujatha Venkataraman, Julie R. Park, Sabine Mueller, Brian R. Rood, Eugene I. Hwang, Leo D. Wang, Nicholas A. Vitanza
Publikováno v:
Current Oncology Reports.
Purpose of Review Correlative studies should leverage clinical trial frameworks to conduct biospecimen analyses that provide insight into the bioactivity of the intervention and facilitate iteration toward future trials that further improve patient o
Autor:
Javad Nazarian, Sabine Mueller, Michael Prados, Adam C. Resnick, Roger J. Packer, Michael E. Berens, Winnie S. Liang, Soonmee Cha, Katherine E. Warren, John R. Crawford, Cassie Kline, Eugene I. Hwang, John S. Myseros, Nalin Gupta, Suresh N. Magge, Heather Gordish-Dressman, Madhuri Kambhampati, Mariam S. Aboian, Lindsay B. Kilburn, Eshini Panditharatna
Supplementary figures 1-4 and supplementary table 3. Supplementary figure 1. Genomic DNA validation of probes, assessing sensitivity, and specificity of ddPCR platform. Supplementary figure 2. Novel detection of histone 3 mutation in fluid present in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a128bfb305f03b526907bd58c6330699
https://doi.org/10.1158/1078-0432.22470308
https://doi.org/10.1158/1078-0432.22470308
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Appendix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaefeb9be99647fd51217c8ee4e4797
https://doi.org/10.1158/1078-0432.22454475
https://doi.org/10.1158/1078-0432.22454475
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Figure S1. Sample flow-chart describing the number of biological samples and clinical data obtained through an international multi-institutional effort and the distribution of samples in each microarray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361d41fd9453dbfadfe788305a9f4f51
https://doi.org/10.1158/1078-0432.22454472
https://doi.org/10.1158/1078-0432.22454472