UV Induces GADD45 in a p53-Dependent and -Independent Manner in Human Keratinocytes

Autor: Duane A. Leedel, Le Luong, Eugene G. Chomey, Tomoko Maeda, Victor A. Tron, Adrian B. Sim, Prescillia P. S. Chua

Publikováno v: Journal of Cutaneous Medicine and Surgery. 7:119-123

Background:GADD45 is a multifunctional protein involved in DNA repair and in cell cycle checkpoint control. p53 plays an important role in regulating DNA repair and in response to UVB in keratinocytes.Objective:GADD45 and p53 expression was examined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555f2b14fb30cad3f8dcba3b9e0cbb15
https://doi.org/10.1177/120347540300700204

A global benchmark study using affinity-based biosensors

Autor: Aykut Üren, Stephen G. Brohawn, Eva Muñoz, Kenneth Miller, Mike Scott, Heather Hughes, Yasmina Noubia Abdiche, Rohn Lee Millican, Anne W Emerick, Jonathan Brooks, Michael B. Murphy, Charlene S. Lee, Carmelo Di Primo, Joshua Ballard, Quyhn Trinh, Giuseppe A. Papalia, Cynthia S. Hinck, Kevin Thompson, Peter Flynn, Joshua S. Klein, Martin A. Wear, Mark Toews, Richard N. Bohnsack, Mohammed Yousef, Daniel Malashock, Gaetano Barbato, Jill Raymond, Alison Joyce, Min Hsiang Yang, Julie Rothacker, Patrick England, Ashique Rafique, Jacinto López-Sagaseta, Scott L. Klakamp, Daulet Satpaev, Monica Dines, Danny Terwey, Islay Campbell, Joshua Thompson, Ben Busby, Tanmoy Ganguly, Gerardo Gutierrez-Sanchez, Sergei Shikov, Kevin Lindquist, Momchilo Vuyisich, Asya Grinberg, Krista Witte, Yun Hee Cho, Yue Ji Li, Hubert Mantz, Ewa Pol, Gonzalo Obal, Brian J. Pak, María J. Hernáiz, Peter Kainz, Erk Gedig, Mary M. Murphy, Tsafir Bravman, Janus Krarup, Gabrielle Zeder-Lutz, John Quinn, Thomas E. Ryan, Pietro Brandani, Dawn Kernaghan, Anca Clabbers, M. Brent Waddell, Agnes Puskas, Petr Skládal, Sanjay Nilapwar, Kara Herlihy, Gregor Anderluh, Federico Torta, Eric Hommema, Andrej Bavdek, Rejane Guimaraes, Anthony M. Giannetti, Eric Fang, Henrik Anderson, Anne Birgitte Bagge Hagel, Schuyler B Corry, Mark R. Witmer, Phillippe Neuner, Sébastien Wieckowski, Nico Dankbar, Alanna Pinkerton, Suparna Mundodo, Trevor D. Chapman, Sylvie Canepa, Satya P. Yadav, Rostislav Skrabana, Oleksandr Kalyuzhniy, Phini S Katsamba, Vidya Chandrasekaran, Eugene G. Chomey, Dana Reichmann, Katy McGirr, Dotzlaf Joe Edward, Mireille Baltzinger, Ite A. Laird-Offringa, Liann Wang, Erica Boni, Tiffany Tsang, Zaneta Nikolovska-Coleska, Andreas Schoenemann, Yuki Abe, Jamie Furneisen, Kenneth T. Lewis, Eileen M. Lafer, John Corbin, Satyen Gautam, Yuguo Feng, Olan Dolezal, Sylviane Hoos, James R. Horn, Bianca Beusink, Jinlin Peng, Otto Pritsch, Kristian H. Schlick, Ryan James Darling, Malgorzata Mikolajczyk, Quincy L. Carter, Jason T. Schuman, Yang Liu, Abdelkrim Khadir, Loïc Martin, Mark Alan Lewis, Ganeshram Krishnamoorthy, Andrew W. Drake, Jason Baardsnes, George Korza, Jesper Pass, Judie Berlier, Melicia Gainey, Nguyen Ly, James R. Partridge, Rosy Calvert, Roberta D'Agata, Rebecca L. Rich, Monica E. Ferreira, Phillip Page, Frank John Podlaski, Jay Duffner, Ruchira Das Gupta, Melanie Wong, Sergei Bibikov, Jiejin Li, Paola Torreri, Bruce A. Andrien, Peter Spies, Christina Boozer, David G. Myszka

Publikováno v: Analytical Biochemistry
Analytical Biochemistry, Elsevier Masson, 2009, 386 (2), pp.194-216. ⟨10.1016/j.ab.2008.11.021⟩
Analytical biochemistry, 386(2):10.1016/j.ab.2008.11.021, 194-216. Academic Press Inc.
Analytical Biochemistry, 2009, 386 (2), pp.194-216. ⟨10.1016/j.ab.2008.11.021⟩
Rich, R L, Papalia, G A, Flynn, P J, Furneisen, J, Quinn, J, Klein, J S, Katsamba, P S, Waddell, M B, Scott, M, Thompson, J, Berlier, J, Corry, S, Baltzinger, M, Zeder-Lutz, G, Schoenemann, A, Clabbers, A, Wieckowski, S, Murphy, M M, Page, P, Ryan, T E, Duffner, J, Ganguly, T, Corbin, J, Gautam, S, Anderluh, G, Bavdek, A, Reichmann, D, Yadav, S P, Hommema, E, Pol, E, Drake, A, Klakamp, S, Chapman, T, Kernaghan, D, Miller, K, Schuman, J, Lindquist, K, Herlihy, K, Murphy, M B, Bohnsack, R, Andrien, B, Brandani, P, Terwey, D, Millican, R, Darling, R J, Wang, L, Carter, Q, Dotzlaf, J, Lopez-Sagaseta, J, Campbell, I, Torreri, P, Hoos, S, England, P, Liu, Y, Abdiche, Y, Malashock, D, Pinkerton, A, Wong, M, Lafer, E, Hinck, C, Thompson, K, Primo, C D, Joyce, A, Brooks, J, Torta, F, Bagge Hagel, A B, Krarup, J, Pass, J, Ferreira, M, Shikov, S, Mikolajczyk, M, Abe, Y, Barbato, G, Giannetti, A M, Krishnamoorthy, G, Beusink, B, Satpaev, D, Tsang, T, Fang, E, Partridge, J, Brohawn, S, Horn, J, Pritsch, O, Obal, G, Nilapwar, S, Busby, B, Gutierrez-Sanchez, G, Gupta, R D, Canepa, S, Witte, K, Nikolovska-Coleska, Z, Cho, Y H, D'Agata, R, Schlick, K, Calvert, R, Munoz, E M, Hernaiz, M J, Bravman, T, Dines, M, Yang, M-H, Puskas, A, Boni, E, Li, J, Wear, M, Grinberg, A, Baardsnes, J, Dolezal, O, Gainey, M, Anderson, H, Peng, J, Lewis, M, Spies, P, Trinh, Q, Bibikov, S, Raymond, J, Yousef, M, Chandrasekaran, V, Feng, Y, Emerick, A, Mundodo, S, Guimaraes, R, McGirr, K, Li, Y-J, Hughes, H, Mantz, H, Skrabana, R, Witmer, M, Ballard, J, Martin, L, Skladal, P, Korza, G, Laird-Offringa, I, Lee, C S, Khadir, A, Podlaski, F, Neuner, P, Rothacker, J, Rafique, A, Dankbar, N, Kainz, P, Gedig, E, Vuyisich, M, Boozer, C, Ly, N, Toews, M, Uren, A, Kalyuzhniy, O, Lewis, K, Chomey, E, Pak, B J & Myszka, D G 2009, ' A global benchmark study using affinity-based biosensors ', Analytical Biochemistry, vol. 386, no. 2, pp. 194-216 . https://doi.org/10.1016/j.ab.2008.11.021

International audience; To explore the variability in biosensor studies, 150 participants from 20 countries were given the same protein samples and asked to determine kinetic rate constants for the interaction. We chose a protein system that was amen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f0511d7d5e8ed6e3424eec0c582e12
https://hal.archives-ouvertes.fr/hal-01527917

Caenorhabditis elegans as a model organism in the study of nucleoside transporters

Autor: M. Griffiths, Ian A. Hope, Sylvia Y.M. Yao, D. MacGregor, P.J. Appleford, Carol E. Cass, Eugene G. Chomey, R.E. Isaac, Stephen A. Baldwin, James D. Young, D. Coates

Publikováno v: Biochemical Society Transactions. 30:A44-A44

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5862537b2e9d6abb99f6df0db566b7e8
https://doi.org/10.1042/bst030a044c

Role of p21Waf-1 in Regulating the G1 and G2/M Checkpoints in Ultraviolet-Irradiated Keratinocytes

Autor: Eugene G. Chomey, Tomoko Maeda, Robin A. Espino, Prescillia P. S. Chua, Victor A. Tron, Michelle T. Chong, Jefferey Q. Cao, Le Luong

Publikováno v: Journal of Investigative Dermatology. (2):513-521

This study examines the role of p21(Waf-1) , a p53-dependent protein, in regulating mechanisms that protect keratinocytes against ultraviolet-B-induced cellular damage. Keratinocytes from p21(Waf-1) or p53-deficient mice were irradiated with ultravio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867fcf74574b5ef9df7453319191e5f8