Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Eugene E. Kwan"'
Publikováno v:
Nature. 610(7933)
Research in the field of asymmetric catalysis over the past half century has resulted in landmark advances, enabling the efficient synthesis of chiral building blocks, pharmaceuticals and natural products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ccab08dbf90e18b13afea64904b22c7
https://pubmed.ncbi.nlm.nih.gov/36216948
https://pubmed.ncbi.nlm.nih.gov/36216948
Research in the field of asymmetric catalysis over the past half century has resulted in landmark advances, enabling the efficient synthesis of chiral building blocks, pharmaceuticals, and natural products. A small number of asymmetric catalytic reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233ee2f52d0bcc4721e3f58588a08ae5
https://doi.org/10.26434/chemrxiv-2022-9w88q
https://doi.org/10.26434/chemrxiv-2022-9w88q
Publikováno v:
J Am Chem Soc
We report a strategy for effecting catalytic, enantioselective carbocationic rearrangements through the intermediacy of alkyl iodanes as stereodefined carbocation equivalents. Asymmetric Wagner–Meerwein rearrangements of β-substituted styrenes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfb0ba65af6d448cd7a552150f2e965
https://doi.org/10.1021/jacs.0c08150
https://doi.org/10.1021/jacs.0c08150
Publikováno v:
Journal of the American Chemical Society
Here we demonstrate that highly β-selective glycosylation reactions can be achieved when the electronics of a sulfonyl chloride activator and the reactivity of a glycosyl donor hemiacetal are matched. While these reactions are compatible with the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c1537c5c09d484da8082f99294af82
http://europepmc.org/articles/PMC6814073
http://europepmc.org/articles/PMC6814073
Autor:
Daniel A. Pollack, Michael J. Aziz, Roy G. Gordon, Marc-Antoni Goulet, Liuchuan Tong, Eugene E. Kwan, Susan A. Odom, Alán Aspuru-Guzik, Daniel P. Tabor
Publikováno v:
Journal of the American Chemical Society. 141:8014-8019
Redox flow batteries based on quinone-bearing aqueous electrolytes have emerged as promising systems for energy storage from intermittent renewable sources. The lifetime of these batteries is limited by quinone stability. Here, we confirm that 2,6-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079e5009088ba17909d7c6fc76fd0f33
https://doi.org/10.1021/jacs.8b13295
https://doi.org/10.1021/jacs.8b13295
Autor:
Marc-Antoni Goulet, Liuchuan Tong, Eugene E. Kwan, Daniel A. Pollack, Daniel P. Tabor, Michael J. Aziz, Roy G. Gordon, Alán Aspuru-Guzik, Susan A. Odom
Publikováno v:
Journal of the American Chemical Society. 143:14019-14020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ca18bffeddad809e816af7c670eb05d
https://doi.org/10.1021/jacs.1c05529
https://doi.org/10.1021/jacs.1c05529
Publikováno v:
Nature chemistry
Nucleophilic aromatic substitution (SNAr) is one of the most widely applied reaction classes in pharmaceutical and chemical research, providing a broadly useful platform for the modification of aromatic ring scaffolds. The generally accepted mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00250aa64a37607325ccf1803154c093
http://europepmc.org/articles/PMC6105541
http://europepmc.org/articles/PMC6105541
Publikováno v:
Science. 355:162-166
A cyclic catalyst to pair up sugars Linking sugar molecules together to make complex carbohydrates is a geometrical challenge. For a six-carbon sugar such as glucose, there are six different possible linkage sites and also two possible configurations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c017434484f835603883a695ef04c409
https://doi.org/10.1126/science.aal1875
https://doi.org/10.1126/science.aal1875
Publikováno v:
Journal of the American Chemical Society. 139:43-46
Polarization transfer is demonstrated as a sensitive technique for the measurement of isotopic fractionation of protonated carbons at natural abundance. This method allows kinetic isotope effects (KIEs) to be determined with substantially less materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f93e7caee103a7e0f5d74cd6be9f11
https://doi.org/10.1021/jacs.6b10621
https://doi.org/10.1021/jacs.6b10621
Autor:
Danae Bowen, Adam Langenbucher, Rémi Buisson, Cyril H. Benes, Michael S. Lawrence, Eugene E. Kwan, Lee Zou
Publikováno v:
Science (New York, N.Y.), vol 364, iss 6447
INTRODUCTION: Extensive tumor sequencing efforts have transformed the way in which cancer driver genes are identified. Appropriate statistical modeling is crucial for distinguishing true drivers from passenger events that accumulate during tumorigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c6759b2a4f798a2df68d6c5820d8d5
https://doi.org/10.1126/science.aaw2872
https://doi.org/10.1126/science.aaw2872