Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Eugene D Ponomarev"'
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96256 (2014)
Glatiramer acetate (GA, Copaxone, Copolymer-1) is an FDA approved drug for the treatment of MS and it is very effective in suppressing neuroinflammation in experimental autoimmune encephalitis (EAE), an animal model of MS. Although this drug was desi
Externí odkaz:
https://doaj.org/article/22960034e2fd4051bf5e63f3035003aa
Autor:
Ilya Sotnikov, Tatyana Veremeyko, Sarah C Starossom, Natalia Barteneva, Howard L Weiner, Eugene D Ponomarev
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
[This corrects the article DOI: 10.1371/journal.pone.0058979.].
Externí odkaz:
https://doaj.org/article/c1c35b290ab24d509bea4a55047ef4d9
Autor:
Ilya Sotnikov, Tatyana Veremeyko, Sarah C Starossom, Natalia Barteneva, Howard L Weiner, Eugene D Ponomarev
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58979 (2013)
Platelets respond to vascular damage and contribute to inflammation, but their role in the neurodegenerative diseases is unknown. We found that the systemic administration of brain lipid rafts induced a massive platelet activation and degranulation r
Externí odkaz:
https://doaj.org/article/334e5d5d0b2c4303ba4b381c3ee53080
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81774 (2013)
Monocytic cells exhibit a high level of heterogeneity and have two distinct modes of their activation: 1) classical M1 path associated with inflammation and tissue damage, and 2) alternative M2 path. Although it has been demonstrated that M2 macropha
Externí odkaz:
https://doaj.org/article/6c7baf9c472c41cdad2192060a86c912
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1323 (2024)
Neurologic disorders such as traumatic brain injury, multiple sclerosis, Alzheimer’s disease, and drug-resistant epilepsy have a high socioeconomic impact around the world. Current therapies for these disorders are often not effective. This creates
Externí odkaz:
https://doaj.org/article/39d5c6cf308049cd9f796002df4d765d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Complement system plays an important role in the immune defense against pathogens; however, recent studies demonstrated an important role of complement subunits C1q, C4, and C3 in normal functions of the central nervous system (CNS) such as non-funct
Externí odkaz:
https://doaj.org/article/e4bf86684c5043eba6da748fea0d1119
Autor:
Galina Nugumanova, Eugene D. Ponomarev, Sholpan Askarova, Elizaveta Fasler-Kan, Natasha S. Barteneva
Publikováno v:
Toxins, Vol 15, Iss 3, p 233 (2023)
Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive cyanopeptides in freshwater, marine, and terrestrial ecosystems. The health significance of these metabolites, which include genotoxic- and neurotoxic agents, is con
Externí odkaz:
https://doaj.org/article/cb77dc61224c4b4582a4c0b4dd78308f
Autor:
Polina Len, Gaukhar Iskakova, Zarina Sautbayeva, Aigul Kussanova, Ainur T. Tauekelova, Madina M. Sugralimova, Anar S. Dautbaeva, Meruert M. Abdieva, Eugene D. Ponomarev, Alexander Tikhonov, Makhabbat S. Bekbossynova, Natasha S. Barteneva
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
IntroductionCoagulation parameters are important determinants for COVID-19 infection. We conducted meta-analysis to assess the association between early hemostatic parameters and infection severity.MethodsElectronic search was made for papers that ad
Externí odkaz:
https://doaj.org/article/0f183b6ab2e148b2b5315ddbf2ae3f6e
Autor:
Tatyana Strekalova, Evgeniy Svirin, Ekaterina Veniaminova, Ekaterina Kopeikina, Tatyana Veremeyko, Amanda W.Y. Yung, Andrey Proshin, Susanne Walitza, Daniel C. Anthony, Lee Wei Lim, Klaus-Peter Lesch, Eugene D. Ponomarev
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 16, Iss , Pp 100306- (2021)
Gangliosides are glycosphingolipids, which are abundant in brain, are known to modulate ion channels and cell-to-cell communication. Deficiencies can result in aberrant myelination and altered immune responses, which can give rise to neurodevelopment
Externí odkaz:
https://doaj.org/article/8608672414da4f6d81d931281e3c4f30
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The central nervous system (CNS) is highly vascularized where neuronal cells are located in proximity to endothelial cells, astroglial limitans, and neuronal processes constituting integrated neurovascular units. In contrast to many other organs, the
Externí odkaz:
https://doaj.org/article/cd7fabdecdb147399f6e93020957924a