Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Eugene Cox"'
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Akademický článek
Model-Based Meta-Analysis Supporting the Combination of Acetaminophen and Topical Diclofenac in Acute Pain: A Therapy for Mild-to-Moderate Osteoarthritis Pain?
Autor: Vidhu Sethi, Li Qin, Eugène Cox, Iñaki F. Trocóniz, Oscar Della Pasqua
Publikováno v: Pain and Therapy, Vol 13, Iss 1, Pp 145-159 (2024)
Abstract Introduction Acetaminophen and topical diclofenac (AtopD) have complementary mechanisms of action and are therefore candidates for combination use in osteoarthritis (OA) pain. However, an evidence gap exists on their combination use in OA pa
Externí odkaz: https://doaj.org/article/a5b1eecb883b4f5bacc8fa8db235113e
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4
Akademický článek
Model-Based Assessment of the Liver Safety Profile of Acetaminophen to Support its Combination Use with Topical Diclofenac in Mild-to-Moderate Osteoarthritis Pain
Autor: Vidhu Sethi, Li Qin, Iñaki F. Trocóniz, Luke Van der Laan, Eugène Cox, Oscar Della Pasqua
Publikováno v: Pain and Therapy, Vol 13, Iss 1, Pp 127-143 (2024)
Abstract Introduction The use of combination therapy of oral acetaminophen and topical diclofenac, having complementary mechanisms of action, is an attractive strategy to enhance the analgesic response in osteoarthritis (OA) pain. While topical diclo
Externí odkaz: https://doaj.org/article/0ed00b164eb4444f82633e8861520068
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Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial
Autor: Daniel Franz Lozano Beltran, Sandro Villarroel, Cristina Alonso-Vega, Nair Montano, Jimena Ramos Morales, Alejandro Palacios Lopez, Juan Carlos Ramirez, Tomás Duffy, Margarita Bisio, Alejandro G. Schijman, Lourdes Ortiz, Roxana Challapa Quechover, Silvia Sanz Sender, Paul Matthias Diderichsen, Eugene Cox, Nilce Mendoza, Michel Vaillant, Faustino Torrico, Fabiana Alves, Lineth Garcia, Igor C. Almeida, Gimena Rojas Delgadillo, Lizeth Rojas Panozo, Michael Everson, Maria Yurly Escobar Caballero, Fred Duncanson, Rudy Nelson Vasco Arenas, Isabel Gonzales, Helmut Ramon Magne Anzoleaga, Makoto Asada, Wladimiro Jimenez, Facundo Garcia-Bournisen, David Wesche, Carlos Florencio Hoyos Delfin, Letty Cardozo, Luis Izquierdo, Isabela Ribeiro, Erika Correia, Bethania Blum, Nathalie Strub-Wourgaft, María-Jesús Pinazo, Glaucia Santina, Manuel Morales, Albert Mendoza Zalabar, Joaquim Gascon, Rudy Parrado, Alexandre F. Marques, Antonia Daniels, Joan Carlos Reverter, Jimy Jose Pinto Rocha, Violeta Alejandra Fernandez Galvez, Anabelle de la Barra, Dunia Torrico Terceros, Gabriela Cuellar
Publikováno v: The Lancet Infectious Diseases. 18:419-430
Background: Chagas disease is a major neglected vector-borne disease. In this study, we investigated the safety and efficacy of three oral E1224 (a water-soluble ravuconazole prodrug) regimens and benznidazole versus placebo in adult chronic indeterm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148eb68d473064a3db9cd188eff30caa
https://doi.org/10.1016/s1473-3099(17)30538-8
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JNJ-26481585, a Novel Second-Generation Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity
Autor: Janine Arts, Ann Marien, Willem Talloen, Peter King, Ian Hickson, Ron Gilissen, Kristof Van Emelen, Bruno Roux, Ilse Goris, Laurence Decrane, Wim Floren, Michel Janicot, Luc Andries, Lut Janssen, Martin John Page, Ann Beliën, Eugene Cox, Veronique Vreys, Kees Bol, Patrick Angibaud, Isabelle Noëlle Constance Pilatte, Marc Du Jardin
Publikováno v: Clinical Cancer Research. 15:6841-6851
Purpose: Histone deacetylase (HDAC) inhibitors have shown promising clinical activity in the treatment of hematologic malignancies, but their activity in solid tumor indications has been limited. Most HDAC inhibitors in clinical development only tran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c5bfec2072a023e6d84c76e378f0ea
https://doi.org/10.1158/1078-0432.ccr-09-0547
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Multimedia
Autor: Kyle D. Carpenter, Paul R. Kohn, Edwin H. Carpenter, David Eugene Cox, Frederick H. Wolfe
Publikováno v: Social Science Computer Review. 15:98-114
This article presents information about the process of creating an asynchronous learning experience for postsecondary school students employing a hybrid World Wide Web and CD-ROM technology. The steps include assembling an appropriate studio facility
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e07574b49fe684abfd4f2a6253584616
https://doi.org/10.1177/089443939701500109
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The kingdom of Burgundy, the lands of the house of Savoy and adjacent territories
Autor: Eugene Cox
By the thirteenth century 'kingdom of Burgundy' had become common to apply the term 'Burgundy' only to the northern part, and to refer to the regions from the Viennois southward as the kingdom of Arles. The plan to reconstitute a kingdom of Arles on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80ad3316d45baf787b6120d2a96afd68
https://doi.org/10.1017/chol9780521362894.017
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