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pro vyhledávání: '"Eugene A. Rastorguev"'
Autor:
Eugene A. Rastorguev, Valery S. Kochubey, Ilya I. Afanasyev, Natalya I. Vasilevich, Dmitry V. Genis
Publikováno v:
MedChemComm. 4:1597
A new class of alpha-helix mimetics, based on the phenyl-pyrazole-phenyl (6-5-6) system, has been designed and synthesized. The ability of the new compounds to inhibit PPIs was confirmed using an MDM2-p53 binding assay. The library, containing comple