Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Eugene A. Gibbs-Flournoy"'
Autor:
Randy A. Harrison, James J. Jetter, Lisa B. Copeland, M. Ian Gilmour, I. J. George, Eugene A. Gibbs-Flournoy, Mark Higuchi, Virginia C. Moser, Janice A. Dye
Publikováno v:
Environmental Research. 161:35-48
Background There is an urgent need to provide access to cleaner end user energy technologies for the nearly 40% of the world's population who currently depend on rudimentary cooking and heating systems. Advanced cookstoves (CS) are designed to cut em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3524e991e7b3bfeeb196f090b18a7ba
https://doi.org/10.1016/j.envres.2017.10.043
https://doi.org/10.1016/j.envres.2017.10.043
Autor:
M. Ian Gilmour, Marie M. Hargrove, Eugene A. Gibbs-Flournoy, Charles E. Wood, Yong Ho Kim, Stephen H. Gavett, John K. McGee
Publikováno v:
Inhalation toxicology. 30(11-12)
Exposure to coarse particulate matter (PM) is associated with lung inflammation and exacerbation of respiratory symptoms in sensitive populations, but the degree to which specific emission sources contribute to these effects is unclear. We examined w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fe7ee7e9b9edb7d240baf9dfd51212
https://pubmed.ncbi.nlm.nih.gov/30516399
https://pubmed.ncbi.nlm.nih.gov/30516399
Publikováno v:
Journal of Visualized Experiments.
While oxidative stress is a commonly cited toxicological mechanism, conventional methods to study it suffer from a number of shortcomings, including destruction of the sample, introduction of potential artifacts, and a lack of specificity for the rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897cbca098d7349885b5ef427d135964
https://doi.org/10.3791/56945-v
https://doi.org/10.3791/56945-v
Autor:
Phillip A. Wages, Eugene A. Gibbs-Flournoy, Steven O. Simmons, Philip A. Bromberg, James M. Samet, Elizabeth M. Corteselli, Katelyn S. Lavrich
Publikováno v:
Toxicology and applied pharmacology. 342
Exposure to ambient particulate matter (PM) causes cardiopulmonary morbidity and mortality through mechanisms that involve oxidative stress. 1,2-naphthoquinone (1,2-NQ) is a ubiquitous component of PM and a potent redox-active electrophile. We previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ab2bd2841e0839d137abcca0f7a676
https://pubmed.ncbi.nlm.nih.gov/29407367
https://pubmed.ncbi.nlm.nih.gov/29407367
Autor:
Eugene A. Gibbs-Flournoy, Gary E. Hatch, Katherine Kraft, Joel Norwood, Judy H. Richards, Janice A. Dye
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the US and its impact continues to increase in women. Oxidant insults during critical periods of early life appear to increase risk of COPD through-out the life cours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147169fb4ec14e5b18547f947090789a
https://europepmc.org/articles/PMC7020854/
https://europepmc.org/articles/PMC7020854/
Publikováno v:
Biochimica et biophysica acta. 1860(12)
Background Oxidant stress is arguably a universal feature in toxicology. Research studies on the role of oxidant stress induced by xenobiotic exposures have typically relied on the identification of damaged biomolecules using a variety of conventiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40b0193f21d370a56de6eb0fe6ef979
https://pubmed.ncbi.nlm.nih.gov/27208426
https://pubmed.ncbi.nlm.nih.gov/27208426
Autor:
Lisa A. Dailey, Andrew J. Ghio, Victor L. Roggli, Robert B. Devlin, Eugene A. Gibbs-Flournoy, Amy M. Bern, Danielle J. Padilla-Carlin, Kelly E. Duncan
Publikováno v:
Toxicological Sciences. 118:420-434
Abnormally high incidences of asbestos-related pulmonary disease have been reported in residents of Libby, Montana, because of occupational and environmental exposure to asbestos-contaminated vermiculite. The mechanism by which Libby amphibole (LA) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af53e1cb887be005ac066ea10d38fdc7
https://doi.org/10.1093/toxsci/kfq281
https://doi.org/10.1093/toxsci/kfq281
Autor:
Sally S. White, Erin P. Hines, Suzanne E. Fenton, Jason P. Stanko, Christopher Lau, Eugene A. Gibbs-Flournoy
Publikováno v:
Molecular and Cellular Endocrinology. 304:97-105
The synthetic surfactant, perfluorooctanoic acid (PFOA) is a proven developmental toxicant in mice, causing pregnancy loss, increased neonatal mortality, delayed eye opening, and abnormal mammary gland growth in animals exposed during fetal life. PFO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d725846fa57613e6788130ad4343cb50
https://doi.org/10.1016/j.mce.2009.02.021
https://doi.org/10.1016/j.mce.2009.02.021
Autor:
Paul D. Chastain, Joseph G. Ibrahim, Nancy E. Thomas, John J. McNulty, Marila Cordeiro-Stone, Yingchun Zhou, William K. Kaufmann, David L. Mitchell, Christopher D. Sproul, Eugene A. Gibbs-Flournoy, Shangbang Rao, Dennis A. Simpson, Craig C. Carson
The objective of this study was to assess potential functional attenuation or inactivation of the intra-S checkpoint during melanoma development. Proliferating cultures of skin melanocytes, fibroblasts and melanoma cell lines were exposed to increasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50432fb7a367764184657b4f806b074e
https://europepmc.org/articles/PMC4745347/
https://europepmc.org/articles/PMC4745347/
Autor:
Tobias P. Dick, Eugene A. Gibbs-Flournoy, James M. Samet, Steven O. Simmons, Philip A. Bromberg
Publikováno v:
Environmental Health Perspectives
Background: The toxicity of many xenobiotic compounds is believed to involve oxidative injury to cells. Direct assessment of mechanistic events involved in xenobiotic-induced oxidative stress is not easily achievable. Development of genetically encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a3d07e5cde47cc0ae56b904e940fee