Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Eugene A. Beck"'
Publikováno v:
Thrombosis Research. 81:145-150
Dysfunctional fibrinogen variants have been discovered by prolongation of thrombin and reptilase clotting times and a discrepancy of the functionally and immunologically determined fibrinogen concentration. More than 250 variants have been described
Autor:
Agnes Chapel, Michel Suscillon, Eugene A. Beck, Miha Furlan, Beat A. Perret, Gilbert Hudry-Clergeon, Leone Tranqui-Pouit
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure. 578:155-163
Human factor VIII-related protein precipitates with specific heterologous antibodies directed against purified factor VIII and supports ristocetin-induced aggregation of washed platelets. We purified human factor VIII from cryoprecipitate by subseque
Autor:
Agnes Henschen, T Barbui, H Kaudewitz, Eugene A. Beck, P Hilgard, G G Nenci, P Reber, M. Berrettini, Miha Furlan
Publikováno v:
Thrombosis and Haemostasis. 56:401-406
SummaryWe report on three unrelated individuals with the same uncommon type of dysfibrinogenemia, originating from Bergamo, Essen and Perugia. None of them showed bleeding symptoms while the Bergamo patient and members of her family presented with a
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure. 578:164-174
Human factor VIII-related protein was isolated from cryoprecipitate by agarose (Sepharose CL-2B) gel filtration. Electrophoresis on SDS-2% polyacrylamide-0.5% agarose gels revealed size heterogeneity of factor VIII-related protein which was similar t
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure. 400:112-120
A method is presented for detection of cross-linking acceptor sites on fibrinogen chains, using monodansyl-cadaverine labeling in the presence of activated fibrin stabilizing factor, and polyacrylamide electrophoresis in the presence of sodium dodecy
Publikováno v:
Thrombosis and Haemostasis. 47:118-121
SummaryHuman fibrinogen was subjected to limited proteolytic attack by thrombin, batroxobin or Agkistrodon contortrix thrombin-like enzyme, yielding desAB-, desA- or desB-fibrin monomers, respectively. Turbidity curves demonstrated that, with all thr
Autor:
Eugene A. Beck
Publikováno v:
Thrombosis and Haemostasis. 37:376-379
Publikováno v:
Vox Sanguinis. 35:36-40
Factor VIII-related properties (coagulant = VIII : C, 'Willebrand' factor = VIII R : WF, antigen = VIII R : AG) are measured in a constant proportion in normal plasma and certain preparations of highly purified factor VIII (relative ratios: 0.5--1.5)
Publikováno v:
Thrombosis and Haemostasis. 54:390-393
SummaryAn abnormal fibrinogen, denoted as “fibrinogen Bergamo I”, has been characterized. Its defect consists in an exchange of arginine by cysteine in position 16 of the Aα-chain, thus corresponding to that found in a number of other fibrinogen
Publikováno v:
British Journal of Haematology. 48:319-324
Summary. Platelet aggregating factor (PAF) activity is preferentially associated with the larger molecular forms of bovine factor VIII and diminishes considerably after dissociation into smaller oligomers by mild disulphide reduction. PAF activity wa