Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Eugen J. Schoenle"'
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 63-70 (2013)
Fas (CD95) is a member of the tumor necrosis factor (TNF) receptor superfamily and plays a crucial role in the induction of apoptosis. However, like TNF, Fas can induce nonapoptotic signaling pathways. We previously demonstrated that mice lacking Fas
Externí odkaz:
https://doaj.org/article/31cf8dc88b374c70abb0e9710ff461e3
Autor:
Andreas Neu, Torild Skrivarhaug, Valma Harjutsalo, Valentino Cherubini, Joachim Rosenbauer, Jannet Svensson, Christopher Patterson, Constantin Ionescu-Tirgoviste, Edna Roche, Natasa Rojnic Putarek, C. Castell, Ulrike Rothe, Anders Green, Eugen J. Schoenle, Gisela Dahlquist, Dalė Marčiulionytė, Mirjana Kocova, Roger C Parslow, Gyula Soltész, Birgit Rami-Merhar, Ondrej Cinek, Mira Samardzic, Natasa Bratina, Ilse Weets, Carine E. deBeaufort, Polly J. Bingley, Przemysława Jarosz-Chobot
Publikováno v:
Patterson, C C, Harjutsalo, V, Rosenbauer, J, Neu, A, Cinek, O, Skrivarhaug, T, Rami-Merhar, B, Soltesz, G, Svensson, J, Parslow, R C, Castell, C, Schoenle, E J, Bingley, P J, Dahlquist, G, Jarosz-Chobot, P K, Marčiulionytė, D, Roche, E F, Rothe, U, Bratina, N, Ionescu-Tirgoviste, C, Weets, I, Kocova, M, Cherubini, V, Rojnic Putarek, N, deBeaufort, C E, Samardzic, M & Green, A 2019, ' Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989–2013 : a multicentre prospective registration study ', Diabetologia, vol. 62, no. 3, pp. 408–417 . https://doi.org/10.1007/s00125-018-4763-3
Patterson, C C, Harjutsalo, V, Rosenbauer, J, Neu, A, Cinek, O, Skrivarhaug, T, Rami-Merhar, B, Soltesz, G, Svensson, J, Parslow, R C, Castell, C, Schoenle, E J, Bingley, P J, Dahlquist, G, Jarosz-Chobot, P K, Marčiulionytė, D, Roche, E F, Rothe, U, Bratina, N, Ionescu-Tirgoviste, C, Weets, I, Kocova, M, Cherubini, V, Rojnic Putarek, N, deBeaufort, C E, Samardzic, M & Green, A 2019, ' Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989–2013 : a multicentre prospective registration study ', Diabetologia, vol. 62, no. 3, pp. 408-417 . https://doi.org/10.1007/s00125-018-4763-3
Patterson, C C, Harjutsalo, V, Rosenbauer, J, Neu, A, Cinek, O, Skrivarhaug, T, Rami-Merhar, B, Soltesz, G, Svensson, J, Parslow, R C, Castell, C, Schoenle, E J, Bingley, P J, Dahlquist, G, Jarosz-Chobot, P K, Marčiulionytė, D, Roche, E F, Rothe, U, Bratina, N, Ionescu-Tirgoviste, C, Weets, I, Kocova, M, Cherubini, V, Rojnic Putarek, N, deBeaufort, C E, Samardzic, M & Green, A 2018, ' Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989-2013: a multicentre prospective registration study ', Diabetologia, vol. 62, no. 2017, pp. 408 . https://doi.org/10.1007/s00125-018-4763-3
Diabetologia
Patterson, C C, Harjutsalo, V, Rosenbauer, J, Neu, A, Cinek, O, Skrivarhaug, T, Rami-Merhar, B, Soltesz, G, Svensson, J, Parslow, R C, Castell, C, Schoenle, E J, Bingley, P J, Dahlquist, G, Jarosz-Chobot, P K, Marčiulionytė, D, Roche, E F, Rothe, U, Bratina, N, Ionescu-Tirgoviste, C, Weets, I, Kocova, M, Cherubini, V, Rojnic Putarek, N, deBeaufort, C E, Samardzic, M & Green, A 2019, ' Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989-2013 : a multicentre prospective registration study ', Diabetologia, vol. 62, no. 3, pp. 408-417 . https://doi.org/10.1007/s00125-018-4763-3
Patterson, C C, Harjutsalo, V, Rosenbauer, J, Neu, A, Cinek, O, Skrivarhaug, T, Rami-Merhar, B, Soltesz, G, Svensson, J, Parslow, R C, Castell, C, Schoenle, E J, Bingley, P J, Dahlquist, G, Jarosz-Chobot, P K, Marčiulionytė, D, Roche, E F, Rothe, U, Bratina, N, Ionescu-Tirgoviste, C, Weets, I, Kocova, M, Cherubini, V, Rojnic Putarek, N, deBeaufort, C E, Samardzic, M & Green, A 2019, ' Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989–2013 : a multicentre prospective registration study ', Diabetologia, vol. 62, no. 3, pp. 408-417 . https://doi.org/10.1007/s00125-018-4763-3
Patterson, C C, Harjutsalo, V, Rosenbauer, J, Neu, A, Cinek, O, Skrivarhaug, T, Rami-Merhar, B, Soltesz, G, Svensson, J, Parslow, R C, Castell, C, Schoenle, E J, Bingley, P J, Dahlquist, G, Jarosz-Chobot, P K, Marčiulionytė, D, Roche, E F, Rothe, U, Bratina, N, Ionescu-Tirgoviste, C, Weets, I, Kocova, M, Cherubini, V, Rojnic Putarek, N, deBeaufort, C E, Samardzic, M & Green, A 2018, ' Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989-2013: a multicentre prospective registration study ', Diabetologia, vol. 62, no. 2017, pp. 408 . https://doi.org/10.1007/s00125-018-4763-3
Diabetologia
Patterson, C C, Harjutsalo, V, Rosenbauer, J, Neu, A, Cinek, O, Skrivarhaug, T, Rami-Merhar, B, Soltesz, G, Svensson, J, Parslow, R C, Castell, C, Schoenle, E J, Bingley, P J, Dahlquist, G, Jarosz-Chobot, P K, Marčiulionytė, D, Roche, E F, Rothe, U, Bratina, N, Ionescu-Tirgoviste, C, Weets, I, Kocova, M, Cherubini, V, Rojnic Putarek, N, deBeaufort, C E, Samardzic, M & Green, A 2019, ' Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989-2013 : a multicentre prospective registration study ', Diabetologia, vol. 62, no. 3, pp. 408-417 . https://doi.org/10.1007/s00125-018-4763-3
AIMS/HYPOTHESIS: Against a background of a near-universally increasing incidence of childhood type 1 diabetes, recent reports from some countries suggest a slowing in this increase. Occasional reports also describe cyclical variations in incidence, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d06a8794159c65513c50044d040d20
https://findresearcher.sdu.dk:8443/ws/files/146802856/Trends_and_cyclical_variation_in_the_incidence_of_childhood_type_1_diabetes_in_26_European_centres_in_the_25_year_period_1989_2013.pdf
https://findresearcher.sdu.dk:8443/ws/files/146802856/Trends_and_cyclical_variation_in_the_incidence_of_childhood_type_1_diabetes_in_26_European_centres_in_the_25_year_period_1989_2013.pdf
Autor:
Franziska Phan-Hug, Daniel Konrad, Katharina Spanaus, Maik Welzel, Paul-Martin Holterhus, Eugen J. Schoenle, Dagmar l'Allemand, Mariarosaria Lang-Muritano, Beate Ruecker, Claudia Katschnig
Publikováno v:
Hormone Research in Paediatrics. 84:43-48
Background/Aims: Primary hypoaldosteronism is a rare inborn disorder with life-threatening symptoms in newborns and infants due to an aldosterone synthase defect. Diagnosis is often difficult as the plasma aldosterone concentration (PAC) can remain w
Autor:
Hitoshi Takizawa, Markus G. Manz, Matthias Blüher, Daniel Konrad, Rouven Mueller, Stephan Wueest, Michael S. F. Wiedemann, Larisa V. Kovtonyuk, Flurin Item, Annie S H Chin, Alexander V. Chervonsky, Eugen J. Schoenle
Publikováno v:
EMBO molecular medicine
EMBO Molecular Medicine
EMBO Molecular Medicine
Low-grade inflammation in adipose tissue and liver has been implicated in obesity-associated insulin resistance and type 2 diabetes. Yet, the contribution of inflammatory cells to the pathogenesis of skeletal muscle insulin resistance remains elusive
Publikováno v:
Annales d'endocrinologie. 78(3)
Objective Steroidogenic factor 1 ( SF-1/NR5A1 ) plays a crucial role in regulating adrenal development, gonad determination and differentiation, and in the hypothalamic-pituitary control of reproduction and metabolism. In men (46, XY), it is known th
Autor:
Karin Lange, Peter G.F. Swift, Lynda K. Fisher, Eero A. Kaprio, Moshe Phillip, Fergus J. Cameron, Pål R. Njølstad, Jean Jacques Robert, Timothy Barrett, Eugen J. Schoenle, Luis Castaño, Jan Åman, Henk J. Aanstoot, Andreas Neu, Maurizio Vanelli, Tatsuhiko Urukami, Harry Dorchy, Hilary Hoey, Mirjana Kocova, Carine de Beaufort, Franco Chiarelli, Thomas Danne, Henrik B. Mortensen
Publikováno v:
Pediatric Diabetes. 14:422-428
Objective: To investigate whether center differences in glycemic control are present in prepubertal children Research Design and Methods: This cross-sectional study involved 18 pediatric centers worldwide. All children, Results: A total of 1133 child
Depot-specific differences in adipocyte insulin sensitivity in mice are diet- and function-dependent
Publikováno v:
Adipocyte
Fat depots of different localization vary in their biological/metabolic function. We recently provided evidence for different regulation of lipolysis between perigonadal and mesenteric adipocytes; in particular insulin-induced suppression of lipolysi
Publikováno v:
American journal of physiology. Endocrinology and metabolism
Given the strong link between visceral adiposity and (hepatic) insulin resistance as well as liver steatosis, it is crucial to characterize obesity-associated alterations in adipocyte function, particularly in fat depots drained to the liver. Yet the
Autor:
Annik Hauri-Hohl, Monika Meyer-Böni, Mariarosaria Lang-Muritano, Anna Biason-Lauber, Eugen J. Schoenle, Mathias Hauri-Hohl
Publikováno v:
Clinical Endocrinology. 75:39-43
Context Aromatase deficiency in females is a rare 46,XX Disorder of Sex Differentiation characterized by a defect in catalyzing ooestrogens from androgens. Objective To better understand this rare disorder, we searched for mutations in the CYP19A1 ge
Autor:
Marc Y. Donath, Alexander V. Chervonsky, Desiree M. Schumann, Daniel Konrad, Julia M. Rytka, Anita Schildknecht, Eugen J. Schoenle, Reto A. Rapold, Ori Nov, Assaf Rudich, Stephan Wueest
Publikováno v:
Journal of Clinical Investigation. 120:191-202
Adipose tissue inflammation is linked to the pathogenesis of insulin resistance. In addition to exerting death-promoting effects, the death receptor Fas (also known as CD95) can activate inflammatory pathways in several cell lines and tissues, althou