Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Eugen E. Nikolsky"'
Autor:
Anastasia A. Borodinova, G. S. Sukhova, Eugen E. Nikolsky, Nadezhda V. Tarasova, Denis V. Abramochkin, L. F. Nurullin, Leonid V. Rosenshtraukh
Publikováno v:
Experimental Physiology. 95:265-273
Acetylcholinesterase (AChE) inhibitors provoke typical cholinergic effects in the isolated right atrium of the rat due to the accumulation of acetylcholine (ACh). Our study was designed to show that in the absence of vagal impulse activity, ACh is re
Publikováno v:
Journal of Neurochemistry. 102:2110-2117
Nitric oxide (NO), previously demonstrated to participate in the regulation of the resting membrane potential in skeletal muscles via muscarinic receptors, also regulates non-quantal acetylcholine (ACh) secretion from rat motor nerve endings. Non-qua
Publikováno v:
Neurochemical Research. 28:443-448
Mathematical modeling was applied to study the dependence of miniature endplate current (MEPC) amplitude and temporal parameters on the values of the rate constants of acetylcholine binding to receptors (k+) when cholinesterase was either active or i
Publikováno v:
Neurochemical Research. 26:891-897
The effects of carbachol (CCh) on the frequency (f) of the miniature endplate potentials were tested at temperatures between 5 and 30°C. Higher CCh concentrations, 1 × 10−5 and 5 × 10−6 M, reduced the f to 60% and the temperature dependence wa
Autor:
N. V. Naumenko, German I. Poletayev, Albert Kh. Urazaev, Eugen E. Nikolsky, František Vyskočil
Publikováno v:
NeuroReport. 8:403-406
MUSCLE fibres of the rat diaphragm kept in a tissue culture medium became depolarized by 8-10 mV within 3 h after denervation. In the presence of carbachol (CB; 5 x 10 -8 M), and acetylcholine (ACh; 5 x 10 -8 M, the post-denervation depolarization wa
Publikováno v:
Life sciences. 91(21-22)
Aims In mammalian myocardium acetylcholine (ACh), neurotransmitter which strikingly affects the cardiomyocytes, can be released from the neurons both via quantal (vesicular) and nonquantal (non-vesicular) mechanism of secretion. Non-quantal release i
Publikováno v:
European Journal of Pharmacology. 263:107-114
Acetylcholine, acetylthiocholine, carbachol, suberyldicholine, propionylcholine, succinylcholine, methylfurmethide and F 2268 were tested on motor nerve ending currents recorded with an extracellular microelectrode. The isolated and transversally cut
Publikováno v:
Pflugers Archiv : European journal of physiology. 463(4)
The presence of M3 cholinoreceptors and their role in mediation of action potential waveform modulation were determined by immunolabeling of receptor proteins and standard microelectrode technique, respectively. The sinoatrial node (SAN), which was d
Autor:
Denis V, Abramochkin, Leniz F, Nurullin, Anastasia A, Borodinova, Nadezhda V, Tarasova, Galina S, Sukhova, Eugen E, Nikolsky, Leonid V, Rosenshtraukh
Publikováno v:
Experimental physiology. 95(2)
Acetylcholinesterase (AChE) inhibitors provoke typical cholinergic effects in the isolated right atrium of the rat due to the accumulation of acetylcholine (ACh). Our study was designed to show that in the absence of vagal impulse activity, ACh is re
Autor:
Lilia O Yagodina, Vladimir V. Zobov, Denis V. Abramochkin, Eugen E. Nikolsky, Leonid V. Rosenshtraukh, Konstantin A. Petrov
Publikováno v:
ResearcherID
We compared the effects of the novel acetylcholinesterase (AChE) inhibitor C-547 on action potential configuration and sinus rhythm in the isolated right atrium preparation of rat with those of armin and neostigmine. Both armin (10(-7), 10(-6), and 1