Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Eugen Damoc"'
Autor:
Noah M. Lancaster, Pavel Sinitcyn, Patrick Forny, Trenton M. Peters-Clarke, Caroline Fecher, Andrew J. Smith, Evgenia Shishkova, Tabiwang N. Arrey, Anna Pashkova, Margaret Lea Robinson, Nicholas Arp, Jing Fan, Juli Hansen, Andrea Galmozzi, Lia R. Serrano, Julie Rojas, Audrey P. Gasch, Michael S. Westphall, Hamish Stewart, Christian Hock, Eugen Damoc, David J. Pagliarini, Vlad Zabrouskov, Joshua J. Coon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Owing to its roles in cellular signal transduction, protein phosphorylation plays critical roles in myriad cell processes. That said, detecting and quantifying protein phosphorylation has remained a challenge. We describe the use of a novel
Externí odkaz:
https://doaj.org/article/06a4611f710d4885ae910c3dc977ec18
Autor:
Michiel van de Waterbeemd, Sem Tamara, Kyle L. Fort, Eugen Damoc, Vojtech Franc, Philipp Bieri, Martin Itten, Alexander Makarov, Nenad Ban, Albert J. R. Heck
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The authors demonstrate a 3-tier mass spectrometry approach, including bottom-up and top-down proteomics, as well as native mass spectrometry to provide a detailed description of proteoforms, protein processing and post-translational modifications pr
Externí odkaz:
https://doaj.org/article/0c0527d0c8a64ff9af99b7c55f342e66
Autor:
Therese Wohlschlager, Kai Scheffler, Ines C. Forstenlehner, Wolfgang Skala, Stefan Senn, Eugen Damoc, Johann Holzmann, Christian G. Huber
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The specific glycosylation patterns of biological drugs often impact the efficacy and safety of the therapeutic product. Here the authors describe a native mass spectrometry approach that allows the resolution of highly complex glycosylation patterns
Externí odkaz:
https://doaj.org/article/652a3252f9884ca095fe82ff547d3b84
Publikováno v:
International Journal of Mass Spectrometry
Experiments on a modified Orbitrap Exploris instrument have shown that even in a compact instrument it is possible to achieve a resolving power in excess of 2,000,000 when appropriate tolerance and tuning requirements are met. Such levels are achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76617b27ab301e02818dcaf04199ce5
https://zenodo.org/record/7602059
https://zenodo.org/record/7602059
Autor:
Jan-Peter Hauschild, Amelia Peterson, Erik Couzijn, Eduard Denisov, Denis Chernyshev, Christian Hock, Hamish Stewart, Ralf Hartmer, Dmitry Grinfeld, Christian Thoeing, Bastian Reitemeier, Arne Kreutzmann, Oliver Lange, Wilko Balschun, Aivaras Venckus, Sebastian Kanngiesser, Alexander Kholomeev, Gregor Quiring, Frank Czemper, Eloy Wouters, Michael Belford, Mathias Mueller, Jens Grote, Tabiwang N Arrey, Julia Kraegenbring, Kerstin Strupat, Markus Kellmann, Siegrun Mohring, Catharina Crone, Alexander Harder, Aaron M. Robitaille, Khatereh Motamedchaboki, Yang Liu, Aaron S. Gajadhar, Daniel Lopez Ferrer, Eugen Damoc, Angela Criscuolo, Kristina Srzentic, Ed George, Charles Yang, Ioanna Ntai, Amanda Souza, Andreas Wieghaus, Alexander Makarov
The rapidly increasing adoption of high-resolution accurate-mass methods in analytical laboratories has fueled demand for instruments that combine high performance and reliability with small size and greater ease-of-use. This paper presents the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::e81a54ac1731d5af021a9541096c15fb
https://zenodo.org/record/7602153
https://zenodo.org/record/7602153
Autor:
Eduardo Morgado Schmidt, Eugen Damoc, Alexander Makarov, Marcos A. Pudenzi, Ygor dos Santos Rocha, Rosana C. L. Pereira, Célio F. F. Angolini, Jandyson M. Santos, Eduard Denisov, Marcos N. Eberlin
Publikováno v:
RSC Advances. 8:6183-6191
The performance of the high-field MegaOrbitrap Fourier transform mass spectrometer (FT-MS) with electrospray ionization (ESI) was evaluated to perform petroleum sample characterization via classical petroleomics approaches. Pertinent parameters that
Autor:
Pavel A. Pevzner, Alain Beck, Yury O. Tsybin, Konstantin Aizikov, Luca Fornelli, Alexander Makarov, Daniel Ayoub, Xiaowen Liu, Eugen Damoc
Publikováno v:
Journal of Proteomics. 159:67-76
The increasing importance of immunoglobulins G (IgGs) as biotherapeutics calls for improved structural characterization methods designed for these large (similar to 150 kDa) macromolecules. Analysis workflows have to be rapid, robust, and require min
Autor:
Colin Kleanthous, Beili Wu, Eugen Damoc, Cherine Bechara, Mikhail E. Belov, Nicholas G. Housden, Alexander Makarov, Carol V. Robinson, Jonathan T. S. Hopper, Kallol Gupta, Weston B. Struwe, Idlir Liko, Todd H. Mize, Joseph Gault, Michael T. Marty, Joseph A. C. Donlan, Ya Zhu
Publikováno v:
Nature methods
Small molecules are known to stabilize membrane proteins and to modulate their function and oligomeric state, but such interactions are often hard to precisely define. Here we develop and apply a high-resolution, Orbitrap mass spectrometry-based meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d58ea880c993eb9b5373e10f0b7c014
https://doi.org/10.1038/nmeth.3771
https://doi.org/10.1038/nmeth.3771
Autor:
Eduardo M, Schmidt, Marcos A, Pudenzi, Jandyson M, Santos, Celio F F, Angolini, Rosana C L, Pereira, Ygor S, Rocha, Eduard, Denisov, Eugen, Damoc, Alexander, Makarov, Marcos N, Eberlin
Publikováno v:
RSC advances. 8(11)
The performance of the high-field MegaOrbitrap Fourier transform mass spectrometer (FT-MS) with electrospray ionization (ESI) was evaluated to perform petroleum sample characterization
Publikováno v:
International Journal of Mass Spectrometry. 377:338-344
A novel method for processing of periodic signals, which combines absorption spectra presentation with magnitude spectra and finite-impulse-response filtering, is applied to image current transients acquired in Orbitrap mass spectrometry. Phasing of