Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Eugène T. Dillon"'
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Mesenchymal stromal cells (MSCs) are multipotent progenitors supporting bone marrow hematopoiesis. MSCs have an efficient DNA damage response (DDR) and are consequently relatively radio-resistant cells. Therefore, MSCs are key to hematopoietic recons
Externí odkaz:
https://doaj.org/article/92f7c9fba74f4faa94d2cdfd060df0d3
Autor:
Valentina Tonelotto, Marcel Costa-Garcia, Eve O’Reilly, Kaelin Francis Smith, Kayleigh Slater, Eugene T. Dillon, Marzia Pendino, Catherine Higgins, Paola Sist, Rosa Bosch, Sabina Passamonti, Josep M. Piulats, Alberto Villanueva, Federica Tramer, Luca Vanella, Michelle Carey, Breandán N. Kennedy
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-18 (2024)
Abstract Uveal melanoma (UM) is an ocular cancer, with propensity for lethal liver metastases. When metastatic UM (MUM) occurs, as few as 8% of patients survive beyond two years. Efficacious treatments for MUM are urgently needed. 1,4-dihydroxy quini
Externí odkaz:
https://doaj.org/article/a9bd8fb17964483389a107365ee28f49
Autor:
Sarina Kajani, Sean Curley, Marcella E. O'Reilly, Xiaofei Yin, Eugene T. Dillon, Weili Guo, Kanishka N. Nilaweera, Lorraine Brennan, Helen M. Roche, Fiona C. McGillicuddy
Publikováno v:
Molecular Metabolism, Vol 56, Iss , Pp 101425- (2022)
Introduction: High-fat diet (HFD)-induced obesity impairs clearance of cholesterol through the Reverse Cholesterol Transport (RCT) pathway, with downregulation in hepatic expression of cholesterol and bile acid transporters, namely ABCG5/8 and ABCB11
Externí odkaz:
https://doaj.org/article/9a74e5c821be49dc9efd9343bc31251f
Autor:
Kevin Molloy, Gerard Cagney, Eugene T. Dillon, Kieran Wynne, Catherine M. Greene, Noel G. McElvaney
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Stenotrophomonas maltophilia is a Gram-negative opportunistic pathogen that can chronically colonize the lungs of people with cystic fibrosis (CF) and is associated with lethal pulmonary hemorrhage in immunocompromised patients. Its secreted virulenc
Externí odkaz:
https://doaj.org/article/93040cf73c8940c29ae58c8535d37c60
Autor:
Kevin Molloy, Stephen G. Smith, Gerard Cagney, Eugene T. Dillon, Catherine M. Greene, Noel G. McElvaney
Publikováno v:
Pathogens, Vol 8, Iss 3, p 92 (2019)
Stenotrophomonas maltophilia is an emerging global opportunistic pathogen that has been appearing with increasing prevalence in cystic fibrosis (CF). A secreted protease from S. maltophilia has been reported as its chief potential virulence factor. H
Externí odkaz:
https://doaj.org/article/35669acd8e524fc190c48fe21d5b90a4
Autor:
Gerard L Brien, David Remillard, Junwei Shi, Matthew L Hemming, Jonathon Chabon, Kieran Wynne, Eugène T Dillon, Gerard Cagney, Guido Van Mierlo, Marijke P Baltissen, Michiel Vermeulen, Jun Qi, Stefan Fröhling, Nathanael S Gray, James E Bradner, Christopher R Vakoc, Scott A Armstrong
Publikováno v:
eLife, Vol 7 (2018)
Synovial sarcoma tumours contain a characteristic fusion protein, SS18-SSX, which drives disease development. Targeting oncogenic fusion proteins presents an attractive therapeutic opportunity. However, SS18-SSX has proven intractable for therapeutic
Externí odkaz:
https://doaj.org/article/040d36fc2fea4222ba08bffcd5dcf5a3